A5102730204- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Cardiac Valve Diseases and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Effects of Exercise
- Cardiovascular Function and Risk Factors
- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Cardiac Structural Anomalies and Repair
- Cancer, Hypoxia, and Metabolism
- Medical Imaging Techniques and Applications
- Radiopharmaceutical Chemistry and Applications
- Machine Learning in Healthcare
- Adolescent and Pediatric Healthcare
- Data Quality and Management
- Genetic Neurodegenerative Diseases
- Thermal Regulation in Medicine
- Maternal and fetal healthcare
- European Monetary and Fiscal Policies
- Cardiac, Anesthesia and Surgical Outcomes
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- German Economic Analysis & Policies
- Neurological and metabolic disorders
- Transplantation: Methods and Outcomes
Jena University Hospital
2023-2024
University of St. Gallen
2024
Friedrich Schiller University Jena
2019-2024
Ludwig-Maximilians-Universität München
2022
LMU Klinikum
2022
Klinik und Poliklinik für Frauenheilkunde und Geburtshilfe
2022
Charité - Universitätsmedizin Berlin
2011-2022
Klinik für Frauenheilkunde
2022
Leipzig Heart Institute
2016-2020
University Medical Center of the Johannes Gutenberg University Mainz
2020
Abstract Background and aims Deciding when to repeat stop transarterial chemoembolization (TACE) in patients with hepatocellular carcinoma (HCC) can be difficult even for experienced investigators. Our aim was develop a survival prediction model such undergoing TACE using novel machine learning algorithms compare it conventional scores, ART, ABCR SNACOR. Methods For this retrospective analysis, 282 who underwent HCC at our tertiary referral centre between January 2005 December 2017 were...
The glutamic acid derivative (<i>S</i>)-4-(3-<sup>18</sup>F-Fluoropropyl)-l-glutamic (<sup>18</sup>F-FSPG, alias BAY 94-9392), a new PET tracer for the detection of malignant diseases, displayed promising results in non–small cell lung cancer patients. aim this study was to provide dosimetry estimates <sup>18</sup>F-FSPG based on human whole-body PET/CT measurements. <b>Methods:</b><sup>18</sup>F-FSPG prepared by fully automated 2-step procedure and purified solid-phase extraction method....
Idiopathic cervical dystonia (CD) is a chronic movement disorder characterized by impressive clinical symptoms and the lack of clear pathological findings in diagnostics imaging. At present, injection botulinum toxin (BNT) dystonic muscles an effective therapy to control motor pain CD. We hypothesized that, although it locally injected muscles, BNT application leads changes brain network activity towards normal function. Using 3 T functional MR imaging along with advanced analysis techniques...
Abstract Background Clinical research, particularly in scientific data, grapples with the efficient management of multimodal and longitudinal clinical data. Especially neuroscience, volume heterogeneous data challenges researchers. While current research systems offer rich functionality, they suffer from architectural complexity that makes them difficult to install maintain require extensive user training. Objectives The focus is development presentation a approach specifically tailored for...
Reflex vasovagal-or cardioinhibitory syncope is known to be a major cause of recurrent in children. The mechanism vasovagal (VVS) an interaction between vagally mediated bradycardia or asystole and more less manifest vasodilatory component. Although pacing not advisable as standard approach patients with VVS, it remains treatment option last resort exceptionally severe cases, contraindication refractoriness drug therapy life style changes. To effectively avoid VVS these patients, the...
Key clinical message Adverse effects of amiodarone are rarely seen in pediatric patients, but may occur if is applied for long‐term treatment. Two rather rare phenomena blue‐gray skin pigmentation and pulmonary mass. They represent important differential diagnoses from more common complications like pneumonia drug‐induced toxic lesions.
Bradycardic arrhythmias requiring pacemaker (PM) implantation are still common in patients need of tricuspid valve replacement (TVR). Leaving an existing PM lead extravalvular position may represent a helpful alternative special situations like the mechanical TV. This study aimed to examine short- mid-term outcome paravalvular leads concerning survival and prosthesis dysfunction after TVR.A retrospective case-control with TVR ventricular pacing was conducted. Patients from database Leipzig...
The implantation of a pacemaker or an implantable cardioverter-defibrillator during childhood may reduce quality life and lead to mental health problems. This study aimed evaluate potential problems (i.e., depressive anxiety symptoms) in children with cardiac active devices comparison healthy peers.We analysed data pacemakers cardioverter-defibrillators aged 6-18 years. Quality life, symptoms were assessed by standardised questionnaires. results compared age-matched reference groups.Children...
Abstract Objective Early diagnosis of ischemic stroke is crucial. While CT scans are recommended, interpreting them challenging. Machine learning can aid interpretation, but the lack large datasets hinders its development. We explored if non‐expert labeling enhances performance a deep system trained on expert‐labeled datasets. Methods One‐hundred eight were labeled for suspected strokes by both an expert and non‐expert. A DenseNet121 model was either data alone or with added data. Both...
Tricuspid valve (TV) surgery represents a complex consideration regarding lead management in patients with transvenous ICD. The presented case shows favorable short-term results after sparing TV replacement, leaving an ICD paravalvular position. described technique can be used challenging cases of replacement.
In our multidisciplinary memory center at Jena University Hospital, we initiated a regular video consultation for patients risk of developing dementia or with disease and their relatives the beginning SARS-CoV2 pandemic in spring 2020.Over 12-month period, conducted systematic survey satisfaction among face-to-face contact (F2F) consultations (VC).The aim this study was to evaluate potential use telemedicine older people incipient cognitive deficits context dementia. particular, aimed...
The standard 12-lead electrocardiogram (ECG) remains a widely used tool in the basic cardiac evaluation of children and adolescents. With emergence inherited arrhythmia syndromes, period repolarization has been focus attention. So far, data on its normal variants healthy are scarce. This may cause uncertainties differentiation between pathologies variants. As abnormal autonomic regulation seems to be major influencing factor repolarization, this study aimed evaluate parameters extremely good...
We report the use of Abbott three-dimensional mapping system (EnSite Precision) for placement an atrial pacemaker lead in a patient after modified Fontan procedure. The was used identification promising pacing site complexly right atrium and to visualize successful at same spot.
Key Clinical Message Supraventricular arrhythmias in neonates are rare and mostly not related to structural heart defects. We present the first case of a newborn with supraventricular microreentrant tachycardia possibly associated an atrial septum aneurysm emphasize importance thorough diagnostic workup allowing fast adequate therapy.
Clinical introduction A 2-month-old baby boy was referred to our centre due tachycardia and acute heart failure. The ECG showed a narrow complex with rate of 300 beats per minute (Figure 1). Echocardiographically, patent foramen ovale parachute mitral valve mild regurgitation were diagnosed; cardiac function highly impaired. Figure 1 (50 mm/s) showing the small tachycardia. Question Which following is most likely diagnosis? Ectopic atrial Atrial flutter Chaotic Focal micro re-entrant fibrillation
Huber, Wolfgang1; Eckmann, Maximilian2; Gruber, Andrea2; Klein, Ines2; Elkmann, Felicia2; Putko, Katarzyna2; Wagner, Franziska2; Schuster, Hanna2; Schmid, Roland3; Busch, Daniel2 Author Information