A5101601544- Antibiotic Use and Resistance
- Pneumonia and Respiratory Infections
- Nasal Surgery and Airway Studies
- Hair Growth and Disorders
- Lipid metabolism and disorders
- Bird parasitology and diseases
- Microbial Metabolic Engineering and Bioproduction
- Workplace Spirituality and Leadership
- Viral Infections and Vectors
- Genetic Associations and Epidemiology
- Genetic Syndromes and Imprinting
- Enzyme Catalysis and Immobilization
- Parvovirus B19 Infection Studies
- Nanocomposite Films for Food Packaging
- Antimicrobial agents and applications
- Electromagnetic wave absorption materials
- Extracellular vesicles in disease
- Magnetic Properties and Synthesis of Ferrites
- Hedgehog Signaling Pathway Studies
- Skin Diseases and Diabetes
- Microbial infections and disease research
- Genetic diversity and population structure
- Dyeing and Modifying Textile Fibers
- MicroRNA in disease regulation
- Wnt/β-catenin signaling in development and cancer
Hazara University
2024
University of Balochistan
2017-2024
University of Faisalabad
2024
Aga Khan University
2021
University Research Co (United States)
2021
Czech Academy of Sciences, Institute of Microbiology
2018
Jawaharlal Nehru Medical College Hospital
2017
Wellcome Sanger Institute
2010
Objective: To evaluate health professionals' attitudes, knowledge, and related variables regarding patient confidentiality. Study Design: Institution Based Cross-sectional study. Setting: Gomal Medical College Affiliated Hospitals. Period: June-September 2024. Methods: Using the stratified random sampling approach, 213 people made up sample. Bi-variate multi-variate binary logistic regression analyses were done. Odds ratio, with 95% confidence level P value calculated. Results: Among...
The depletion of non-renewable fossil fuels and a surge in their prices have led researchers to seek alternative, renewable energy sources; among them, biodiesel is good option, especially the ever-growing global transport sector. Mustard oil potential feedstock for production, because it non-edible avoids food versus fuel feud. Biocatalytic transesterification mustard production makes this process cost efficient, environmentally friendly sustainable. In current study, Pseudomanas aeruginosa...
Evidence is sparse about the genetic determinants of major lipids in Pakistanis.Variants (n=45 000) across 2000 genes were assessed 3200 Pakistanis and compared with 2450 Germans using same gene array similar lipid assays. We also did a meta-analysis selected lipid-related variants Europeans. Pakistani architecture was distinct from that several ethnic groups represented international reference samples. Forty-one at 14 loci significantly associated levels HDL-C, triglyceride, or LDL-C. The...
This study aims to analyze the influence of organizational justice (OJ) on job performance (JP) intention via mediating high-performance human resource practices (HPHRPs) in a developing context. Equity theory and expectancy are widely employed many disciplines but seldom applied JP among Pakistan Telecommunication Limited (PTCL) employees. The respondents this were 377 employees working PTCL. Partial least square (PLS), specifically ̣ structural equation modeling was used for data analysis....
Cholesterol is a waxy substance present in all types of the body cells. The presence higher concentration low density lipoprotein (LDL) characterized by abnormal cholesterol level and associated with cardiovascular diseases which lead to development atheroma arteries known as atherosclerosis. transformation bacterial oxidase can provide key solution for treatment related its oxidized derivatives. Previously isolated bacteria from oil-contaminated soil were screened degradation. Among...
Abstract Objective Bacterial infections are known to complicate respiratory viral and associated with adverse outcomes in COVID-19 patients. A case control study was conducted determine risk factors for bacterial where cases were defined as moderate severe/critical patients infection those without included controls. Logistic regression analysis performed. Results Out of a total 50 controls, greater proportion had severe or critical disease at presentation compared i.e 80% vs 30%...
Abstract Staphylococcus aureus is an important foodborne pathogen associated to food intoxication and other multiple infections in human being. Its presence salted a serious issue due its salt tolerance potential. A study was conducted analyze the of enterotoxins producing drug resistance S. sea fish from Gwadar. Freshly persevered samples (n=50) were subjected using 16S rRNA Nuc genes primers. The isolates then evaluated for potential specific primers MecA (methicillin gene), (SEA)...
The present study was conducted to get more information about the genome and locate taxonomic position of Schizothorax niger in Schizothoracinae through mitochondrial 13 protein‐coding genes (PCGs). These PCGs for S. were found be 11409 bps length ranging from 165 (ATPase 8) 1824 (NADH dehydrogenase subunit 5) encode 3801 amino acids. In these PCGs, 4 overlap on similar strands, while one shown opposite one: ATPase 6+8 NADH 4+4L by 7 nucleotides. Similarly, ND5‐ND6 nucleotides, ATP6 COIII 1...
We identified a novel homozygous disease-causing variant in TMC8 Pakistani family with epidermodysplasia verruciformis (EV). The phenotype of EV the affected individuals was most probably caused by an aberrant splicing process. molecular genetic findings our patients expand mutational spectrum disease.
Abstract Background Autosomal recessive wooly hair/hypotrichosis is an inherited disorder of hair characterized by less dense, short, and tightly curled on the scalp sometimes dense to complete absence eyebrows eyelashes. phenotypes are mostly associated with pathogenic sequence variants in LIPH LPAR 6 genes. Methods To find out molecular basis disease, five families autosomal were recruited for genetic analysis. Direct Sanger sequencing genes was carried using BigDye chain termination...
A study was conducted to determine the prevalence and drug resistance of Escherichia coli present in urinary tract infected patients hospital drinking water. total eighty urine samples from clinically suspected thirty tap water vicinity were collected analyzed for presence E. coli. The isolates preliminary identified based on morphological characteristics, biochemical test further confirmed by polymerase chain reaction (PCR) using uidA primer. Isolates subjected antibiogram studies (ESBL...
Dengue is a public health problem and leading mosquito-borne viral disease. In Pakistan, the dengue virus has been source of several epidemics. Objective: To find frequency, distribution, association KAP regarding fever among students with gender type Students. Methods: This descriptive cross-sectional study using stratified random sampling was conducted in General Medical Council (GMC). Sample size 235, an equal proportion from each class were randomly selected. Data analyzed by SPSS...
To meet the requirements of second generation photovoltaics, spin coating and RF magnetron sputtering techniques have been utilized to fabricate zinc sulfide thin films for buffer layer optimization. During fabrication process, substrate temperatures processes are kept at room temperature 200 oC, respectively. Thin annealed 500oC 1 hour in an inert environment acquire crystallinity uniform surface morphology. XRD analysis reveals that fabricated by exhibit wurtzite blende crystal structures,...
Infectious Coryza (IC) was a contagious respiratory bacterial infection in peacocks. The current study evaluated the outcomes of treating infectious coryza peacock. adult peacock at age 2 years presented with history anorexia, difficulty breathing, sticky eyes, nasal and ocular discharge, semi-solid swelling under eyes. Clinical examination confirmed depression, swollen head face, gasping, occluded eyelids, purulent discharge from eyes nostrils, moist rales, recumbency. Treatment included...
Autosomal recessive dystrophic epidermolysis bullosa (RDEB) is a severe form of an inherited skin disorder. RDEB segregates both in autosomal dominant as well pattern. It has been shown that forms (DEB) are caused by mutations the COL7A1 gene. In this study, we investigated consanguineous four-generation family with two individuals displaying phenotype. Both patients showed multiple erosions, atrophic scares, crusted scaling, and pseudosyndactyly. Whole exome sequencing (WES) was performed...
Calcium substituted strontium M-Type hexaferrites are synthesized at different calcium concentrations by co-precipitation method. During synthesis process, PH value of 11 is achieved and solution heated 70 °C for 3 hours to form gel followed drying process 80 5 hours. Synthesized samples then sintered 650 4 ramp rate 10 °C/min. XRD analysis reveals that all exhibit single phase hexagonal crystal structure. Change in density observed 800 as compared due increase temperature. SEM shows the...
EDSS1, a syndrome characterized by ectodermal dysplasia-syndactyly, is inherited in an autosomal recessive manner due to mutations the NECTIN4/PVRL4 gene. Clinical manifestations of include defective nail plate, sparse absent scalp and body hair, spaced teeth with enamel hypoplasia, bilateral cutaneous syndactyly fingers toes. Here, we report consanguineous family Kashmiri origin presenting features EDSS1. Using whole exome sequencing, found recurrent nonsense mutation (NM_030916: c.181C...
ABSTRACT Objective Bacterial infections are known to complicate respiratory viral and associated with adverse outcomes in COVID-19 patients. A case control study was conducted determine risk factors for bacterial where cases were defined as moderate severe/critical patients infection those without included controls. Logistic regression analysis performed. Results Out of a total 50 controls, greater proportion had severe or critical disease at presentation compared i.e 80% vs 30%...
Background. Bardet-Biedl syndrome (BBS) is a rare autosomal recessive inherited disorder with distinctive clinical feature such as obesity, degeneration of retina, polydactyly, and renal abnormalities. The study was aimed at finding out the disease-causing variant/s in patients exhibiting features BBS. Methods. identification variant done by using whole exome sequencing on Illumina HiSeq 4000 platform involving SeqCap EZ Exome v3 kit (Roche NimbleGen). identified further validated Sanger...
Studies on the human skin microanatomy are few and contradictory.Using fetal of different age group, doing H & E staining followed by correlative light microscopy serial tissue sections, comparing it at age, we studied topographic fetuses.Histomorphology was compared from 8 weeks gestation upto 30 last menstrual period (LMP).We found that epidermal differentiation begins gestation.A single layer cells covers embryos up to 9 after LMP.At weeks, periderm is also visible it's called as a double...