A5009482801- Nanoparticles: synthesis and applications
- Plant Pathogens and Fungal Diseases
- Medicinal Plants and Neuroprotection
- Natural Antidiabetic Agents Studies
- Silk-based biomaterials and applications
- Nanoparticle-Based Drug Delivery
- Vitamin C and Antioxidants Research
- Radioactive element chemistry and processing
- Essential Oils and Antimicrobial Activity
- Hedgehog Signaling Pathway Studies
- RNA regulation and disease
- Nanocomposite Films for Food Packaging
- Berberine and alkaloids research
- Genetic and Kidney Cyst Diseases
- Covalent Organic Framework Applications
- Wnt/β-catenin signaling in development and cancer
- Agricultural Practices and Plant Genetics
- Agricultural pest management studies
- Hemoglobinopathies and Related Disorders
- Ethnobotanical and Medicinal Plants Studies
- Synthesis of Organic Compounds
- Genetic Syndromes and Imprinting
- Graphene and Nanomaterials Applications
- Nanomaterials for catalytic reactions
- Multicomponent Synthesis of Heterocycles
Government College University, Lahore
2019-2023
Regroupement Québécois sur les Matériaux de Pointe
2020
Université de Montréal
2019-2020
Abstract Now a day’s multidrug resistance phenomenon has become the main cause for concern and there been an inadequate achievement in development of novel antibiotics to treat bacterial infections. Therefore, is unmet need search adjuvant. Vitamin C one such promising The present study was aimed elucidate antibacterial effect vitamin at various temperatures (4°C, 37°C 50°C) pH (3, 8, 11), against Gram-positive Gram-negative bacteria concentrations (5-20 mg/ml) through agar well diffusion...
The antibacterial activity of synthetic antimicrobial agents is well known, but most them have several side effects and are effective against selective microbes. Recently, major concern for the microbiologists to investigate some stable, non-toxic, cheap, eco-friendly with a wide range bactericidal potential. A cost-effective environmentally friendly alternate has been proposed in form green synthesized nanoparticles. Present study was designed fabricate sericin-coated silver nanoparticles...
Antioxidants are materials that scavenge or remove free radicals from living systems. The oxidation process ends in the production of radicals. These chief birthplace cancerous cells. Antioxidizing agents radical intermediates by terminating processes being oxidized themselves. On other hand, infectious diseases affect world on a large scale. To fight these several synthetic compounds have been used. Plant based medications play important role this regard. So, current research aimed to...
pH-sensitive doxycycline gold nanoparticles (doxy-AuNPs) are reported here to act as effective drug nanocarriers and biocatalysts. The AuNPs were synthesized with doxy the reducing capping agent. Various parameters optimized find best conditions for synthesis of doxy-AuNPs, these characterized UV-vis, X-ray diffraction (XRD), FTIR, transmission electron microscopy (TEM). Doxy-AuNPs then loaded anticancer doxorubicin (DOX), where 70% initially available was within 24 h. Furthermore,...
In clinical chemistry, frequent monitoring of drug levels in patients has gained considerable importance because the benefits on human health, such as avoidance high risk over dosage or increased therapeutic efficacy. this work, we demonstrate that doxycycline can act an Au nanoparticle (doxy-AuNP) growth and capping agent to enhance response a surface plasmon resonance (SPR) biosensor for drug. SPR analysis revealed sensitivity doxy-AuNPs towards detection free doxycycline. More...
Diabetes is a life-threatening disease, and chronic diabetes affects parts of the body including liver, kidney, pancreas. The root cause mainly associated with oxidative stress produced by reactive oxygen species. Minocycline drug multi-substituted phenol ring has shown excellent antioxidant activities. objective present study was to investigate antidiabetic potential minocycline-modified silver nanoparticles (mino/AgNPs) against alloxan-induced diabetic mice. mino/AgNPs were synthesized...
EDSS1, a syndrome characterized by ectodermal dysplasia-syndactyly, is inherited in an autosomal recessive manner due to mutations the NECTIN4/PVRL4 gene. Clinical manifestations of include defective nail plate, sparse absent scalp and body hair, spaced teeth with enamel hypoplasia, bilateral cutaneous syndactyly fingers toes. Here, we report consanguineous family Kashmiri origin presenting features EDSS1. Using whole exome sequencing, found recurrent nonsense mutation (NM_030916: c.181C...
Background. Bardet-Biedl syndrome (BBS) is a rare autosomal recessive inherited disorder with distinctive clinical feature such as obesity, degeneration of retina, polydactyly, and renal abnormalities. The study was aimed at finding out the disease-causing variant/s in patients exhibiting features BBS. Methods. identification variant done by using whole exome sequencing on Illumina HiSeq 4000 platform involving SeqCap EZ Exome v3 kit (Roche NimbleGen). identified further validated Sanger...
Diabetes is a life-threatening disease and chronic diabetes affects the parts of body including liver, kidney pancreas. The root cause mainly associated with oxidative stress produced by reactive oxygen species. minocycline polyphenolic drug excellent antioxidant activities. objective present study was to investigate antidiabetic potential modified silver nanoparticles (Mino/AgNPs) against alloxan-induced diabetic mice. Mino/AgNPs were synthesized using as reducing stabilizing agents....