A5056450531- Phytochemicals and Antioxidant Activities
- Advancements in Transdermal Drug Delivery
- Bee Products Chemical Analysis
- Essential Oils and Antimicrobial Activity
- Skin Protection and Aging
- Biofuel production and bioconversion
- melanin and skin pigmentation
- vaccines and immunoinformatics approaches
- SARS-CoV-2 and COVID-19 Research
- Natural product bioactivities and synthesis
- Microbial Metabolic Engineering and Bioproduction
- Advanced Drug Delivery Systems
- Enzyme Production and Characterization
- Pharmacological Effects of Natural Compounds
- Enzyme Catalysis and Immobilization
- Tea Polyphenols and Effects
- Genomics and Phylogenetic Studies
- Milk Quality and Mastitis in Dairy Cows
- Anaerobic Digestion and Biogas Production
- Biochemical Analysis and Sensing Techniques
- Glycosylation and Glycoproteins Research
- African Botany and Ecology Studies
- Viral Infections and Vectors
- Phytochemical Studies and Bioactivities
- Drug Solubulity and Delivery Systems
Islamia University of Bahawalpur
2014-2025
University of Swat
2017-2024
Gyeongsang National University
2012-2021
Veterinary & Animal Husbandry
2021
Pakistan Council of Scientific & Industrial Research
2020
Liaquat University of Medical & Health Sciences
2016
Isra University
2016
Queen Elizabeth II Hospital
2013
Hamdard University
2006
Plant-derived polyphenols are known to have promising biological activities including antioxidant and antityrosinase may be a potential candidate for anti-dermatoheliotic remedy. The present study was performed investigate the polyphenolic contents of Mimosa pudica (MP) seed extract its using non-invasive biophysical techniques after developing stable topical emulgel formulation. Moreover, in-vitro cytotoxicity also evaluated normal Human keratinocytes (HaCat cells) rule out any cellular...
Synergistic combinations of various antimicrobial agents are considered ideal strategies in combating clinical and multidrug resistant (MDR) infections. In this study, antibacterial potential Jatropha curcas crude seed extracts, oil, commercially available antibiotics, their were investigated for synergistic effect against clinical, MDR ATCC bacterial strains by agar well diffusion assay. Methanolic extracts remained more active Staphylococcus aureus (ATCC), with zone inhibition (ZOI) 21 mm,...
Pirin (PIR) protein is highly conserved in both prokaryotic and eukaryotic organisms. Recently, it has been identified that PIR positively regulates breast cancer cell proliferation, xenograft tumor formation, metastasis, through an enforced transition of G1/S phase the cycle by upregulation E2F1 expression at transcriptional level. Keeping view importance many crucial cellular processes humans, we used a variety computational tools to identify non-synonymous single-nucleotide polymorphisms...
Introduction: The current XBB variant of SARS-CoV-2 with the strongest immune escaping properties is currently most dominant circulating around world. With emergence global morbidities and mortalities have raised again. In scenario, it was highly required to delineate binding capabilities NTD subvariant towards human neutralizing antibodies dig out affinity RBD ACE2 receptor. Materials Methods: study uses molecular interaction simulation-based approaches decipher mechanism mAb spike protein....
Alpha arbutin is a skin-whitening agent in cosmetics. Structurally, it 4-hydroxyphenyl-α-glucopyranoside. Ethosomes encourage the formation of lamellar-shaped vesicles with improved solubility and entrapment whitening agents. The objective this study was to fabricate an optimized nanostructured ethosomal gel loaded alpha for treatment skin pigmentation. Different suspensions were prepared by cold method. Invitro evaluation included zeta potential, droplet size analysis, polydispersity index,...
The utilization of phytoconstituents in skin care products has emerged as a notable trend due to their recognized safety and therapeutic efficacy. However, the challenge lies improving effective delivery specific tissues, primarily attributed poor solubility low permeability. This study endeavors address this by developing, optimizing characterizing Cucumis melo var. agrestis (CME) extract loaded nanoemulsion gel (CME-NEG), aiming enhance permeability antifungal activity. Herein,...
Emulgel is a new innovatory technique for drug development permitting controlled release of active ingredients topical administration. We report stable emulgel 4% Piper nigrum extract (PNE) prepared using 80% ethanol. The PNE-loaded formulation had an antioxidant activity 84% and tyrosinase inhibition was 82%. Prepared rendered spherical-shaped globules with high zeta potential (-45.5 mV) indicative system. Total phenolic contents were 58.01 mg GAE/g dry whereas total flavonoid content 52.63...
The bioactive extracts of traditional medicinal plants are rich in polyphenols and help to rejuvenate skin. study was designed assess the skin rejuvenating effects a stable cream enriched with 4% I. argentea (IaMe) extract. quantity by spectrophotometric methods TPC, 101.55 ± 0.03 mg GAE/g total flavonoid content; 77.14 0.13 QE/g, while HPLC-PDA revealed gallic acid; 4.91, chlorogenic acid 48.12, p-coumaric 0.43, rutin 14.23 μg/g. significant results biological activities were observed as...
The purpose of the study was to prepare a stable multiple emulsion containing skin anti-aging agent and using paraffin oil. Vitamin C, incorporated into inner aqueous phase water-in-oil-in-water (w/o/w) at concentration 1%. Multiple prepared by two step method. Stability studies were performed different accelerated conditions, i.e. 8 oC (in refrigerator), 25 oven), 40 75% RH stability cabin) for 28 days predict formulations. Different parameters, namely pH, globule size, electrical...
A gram-negative, rod-shaped, pale-orange-pigmented bacterial strain with xylan-degrading activity designated YC7004(T) was isolated from a rotten-wood sample collected at Jinju, Korea, and its taxonomic position investigated by using polyphasic approach. The grew optimally on R2A medium 30 °C pH 6. major isoprenoid quinone MK7 fatty acids were summed feature 3, iso-C15 : 0, C16 iso-C17 0 3-OH, 1ω9c 1ω5c. G+C content of the genomic DNA 40.0 mol%. Phylogenetic analysis based 16S rRNA gene...
Antioxidants from natural sources are extensively attaining consideration to avert the skin damage and aging caused by free radicals. Flaxseed (Linum usitatissimum L.), a therapeutic agent, was meant be explored cosmeceutical quantifying its potential phytoconstituents incorporated into microemulgel for topical use. Hydroalcoholic fractions (both methanolic ethanolic; 80%) flaxseed extracts were subjected phytochemical screening total phenolic content (TPC), flavonoid (TFC), high-performance...
The SARS COV-2 and its variants are spreading around the world at an alarming speed, due to higher transmissibility conformational changes caused by mutations. resulting COVID-19 pandemic has imposed severe health consequences on human health. Several countries of including Pakistan have studied genome extensively provided productive findings. In current study, mCSM, DynaMut2, I-Mutant servers were used analyze effect identified mutations structural stability spike protein however, molecular...
The depletion of non-renewable fossil fuels and a surge in their prices have led researchers to seek alternative, renewable energy sources; among them, biodiesel is good option, especially the ever-growing global transport sector. Mustard oil potential feedstock for production, because it non-edible avoids food versus fuel feud. Biocatalytic transesterification mustard production makes this process cost efficient, environmentally friendly sustainable. In current study, Pseudomanas aeruginosa...