A5005797004- Genetic Associations and Epidemiology
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Lipid metabolism and disorders
- Heart Failure Treatment and Management
- Metabolomics and Mass Spectrometry Studies
- Cardiac Arrhythmias and Treatments
- Helicobacter pylori-related gastroenterology studies
- Chronic Disease Management Strategies
- Infective Endocarditis Diagnosis and Management
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Atrial Fibrillation Management and Outcomes
- Erythropoietin and Anemia Treatment
- Coronary Artery Anomalies
- Parkinson's Disease Mechanisms and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Gout, Hyperuricemia, Uric Acid
- Climate Change and Health Impacts
- Systemic Lupus Erythematosus Research
- Dialysis and Renal Disease Management
- Obesity and Health Practices
- Diabetes Management and Education
- Medical Coding and Health Information
Invictus Medical (United States)
2024
Punjab Institute of Cardiology
2007-2021
Wellcome Sanger Institute
2010
The burden of coronary heart disease (CHD) is increasing at a greater rate in South Asia than any other region globally, but there little direct evidence about its determinants. Pakistan Risk Myocardial Infarction Study (PROMIS) an epidemiological resource to enable reliable study genetic, lifestyle and determinants CHD Asia. By March 2009, PROMIS had recruited over 5,000 cases first-ever confirmed acute myocardial infarction (MI) matched controls aged 30–80 years. For each participant,...
Abstract Background Genetic, lifestyle, and environmental factors can lead to perturbations in circulating lipid levels increase the risk of cardiovascular metabolic diseases. However, how changes individual species contribute disease is often unclear. Moreover, little known about role lipids on Pakistan, a population historically underrepresented studies. Methods We characterised genetic architecture human blood lipidome 5662 hospital controls from Pakistan Risk Myocardial Infarction Study...
Evidence is sparse about the genetic determinants of major lipids in Pakistanis.Variants (n=45 000) across 2000 genes were assessed 3200 Pakistanis and compared with 2450 Germans using same gene array similar lipid assays. We also did a meta-analysis selected lipid-related variants Europeans. Pakistani architecture was distinct from that several ethnic groups represented international reference samples. Forty-one at 14 loci significantly associated levels HDL-C, triglyceride, or LDL-C. The...
To determine the frequency of metabolic syndrome in patients with Ischemic Heart Disease (IHD).Cross-sectional, descriptive study.Cardiology Department Punjab Institute Cardiology, Lahore, from June 2006 to 2007.A total 100 subjects ischemic heart disease, fulfilling inclusion criteria, were enrolled study. Demographic data (age and gender) 5 component conditions noted. Subjects physically assessed for abdominal obesity, based on waist circumference. Fasting blood samples glucose lipid...
Results: Two hundred and fifty consecutive patients having tight rheumatic mitral stenosis were studied. The mean age of the study population was 26.9 ± 7.5 years. There more female 128 (51.2%) than males 122 (48.8%). Atrial fibrillation (AF) present less frequently in as 33 (13.2%) had AF compared to 217 (86.8%) sinus rhythm. significantly associated with thrombus formation 23 (60.5%) 15 (39.5%) rhythm p < 0.0001. Thrombus LA commonly visualized on TEE TTE (X 2 =242.3, p=0.0001) mostly...
Objectives: This study was designed to evaluate the pattern of clinical presentation, risk factors and angiographic findingsin young males presenting with acute myocardial infarction (AMI).Materials methodsThis cross-sectional descriptive wasconducted at Cardiology Department, Punjab Institute Cardiology, Lahore from May 2005 till February 2006. After fulfilling inclusioncriteria 200 male patients <40 years coronary artery disease (CAD) were studied. Results: Mean age population...
Objective: To compare the clinical, echocardiographic and angiographicvariables after PTMC in patients of mitral stenosis having echo score < 8 $ 8. Place study: Cardiology wardand echocardiography department Punjab Institute Cardiology, Lahore. Duration The study wasconducted from 15 January 2006 till 30 th July 2006.Study Design: It was a comparative study. Materials &Methods Two hundred consecutive undergoing were studied. Patients dividedin to two groups. Group I consisted patient...
Objectives: The objective of this prospective study was to localize the accessory pathways (AP) in patients with Wolff Parkinson White syndrome (WPW) using algorithm laid down by AP Fitzpatrick, our population. Materials and Methods: 500 consecutive most pre-excited 12 lead ECG sinus rhythm visiting emergency department were analyzed. Delta wave frontal plane vector, polarity V1, height leads I, II Ill sum delta waves polarities II, lII aVF. R size Ill, V1; R/S ratio aVL, S V1 QRS axis...
ABSTRACT Background Genetic, lifestyle, and environmental factors can lead to perturbations in circulating lipid levels increase risk of cardiovascular metabolic diseases. However, how changes individual species contribute disease is often unclear. Moreover, little known about the role lipids on Pakistan, a population historically underrepresented studies. Methods We characterised genetic architecture human blood lipidome 5,662 hospital controls from Pakistan Risk Myocardial Infarction Study...
Objective: To study and compare the in-hospital mortality due to acute myocardial infarction in patients receiving thrombolytic (streptokinase) therapy versus those who were not thrombolysed. Methods: This descriptive observational was conducted at Coronary care Unit Cardiology ward of Nishtar Hospital, Multan, from 1St October 2002 till 30th April 2003. Four hundred thirty four fulfilled WHO criteria included study. Patients divided into two groups: streptokinase (SK) group (Non-SK) group....
Objective: To compare in-hospital mortality of acute myocardial Infarction in patients having normal renal functions with dysfunction patients. Setting: Emergency ward, Coronary care units and cardiology wards the Punjab Institute Cardiology Lahore. Study design: It was a comparative study. Sample size: 1000 consecutive presenting infarction admitted to Lahore were studied from 1st March 2004 15th August 2004. Results: After fulfilling inclusion criteria studied. The mean age study...
Background: Intervention of chronic total coronary artery occlusion is quite challenging. The usual vascular route used in PCI for CTO most cardiac catheterization laboratories through femoral artery. In this study we evaluated the feasibility transradial intervention CTO. Study Design: Interventional descriptive study. Place and Duration Study: Department interventional cardiology Punjab Institute Cardiology, Lahore from July 2007 to Jan-uary 2009. Methods: We examined 170 lesions...