Ana Paula Gameiro Cappelli

ORCID: 0000-0002-8018-0579
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About
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Research Areas
  • Pancreatic function and diabetes
  • Adipose Tissue and Metabolism
  • Birth, Development, and Health
  • Diabetes and associated disorders
  • Diet and metabolism studies
  • Aldose Reductase and Taurine
  • Diet, Metabolism, and Disease
  • Natural Antidiabetic Agents Studies
  • Adipokines, Inflammation, and Metabolic Diseases
  • Metabolism, Diabetes, and Cancer
  • Breastfeeding Practices and Influences
  • Healthcare Systems and Technology
  • Adrenal Hormones and Disorders
  • Diabetes Treatment and Management
  • Microscopic Colitis
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Pancreatic and Hepatic Oncology Research
  • Phytochemicals and Antioxidant Activities
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Mitochondrial Function and Pathology
  • Biochemical Analysis and Sensing Techniques
  • Liver Disease Diagnosis and Treatment
  • Exercise and Physiological Responses
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Diverticular Disease and Complications

Universidade Federal do Maranhão
2016-2020

Università Campus Bio-Medico
2017

Universidade Estadual de Campinas (UNICAMP)
2008-2017

Universidade de São Paulo
2017

Syzygium cumini (L.) Skeels (Myrtaceae) has been traditionally used to treat a number of illnesses. Ethnopharmacological studies have particularly addressed antidiabetic and metabolic-related effects extracts prepared from its different parts, especially seed pulp-fruit, however there is lack on phytochemical profile biological properties leaf. As considerable interest in bioactive compounds metabolic syndrome clustered risk factors, we sought characterize the hydroethanolic extract S. leaf...

10.3389/fphar.2016.00048 article EN cc-by Frontiers in Pharmacology 2016-03-10

Abstract Background & Aims Obese protein malnourished mice display liver insulin resistance and taurine ( TAU ) seems to attenuate this effect. The association between early‐life malnutrition hepatic redox balance in diet‐induced is unknown. We investigated supplementation effects upon state signalling obese mice. Methods Weaned male C57 BL ‐6 were fed a control (14% – C) or protein‐restricted diet (6% R) for 6 weeks. Afterwards, received high‐fat (34% fat HFD 8 weeks CH RH ). Half of...

10.1111/liv.12291 article EN Liver International 2013-07-31

In the present study, we investigated relationship between early life protein malnutrition-induced redox imbalance, and reduced glucose-stimulated insulin secretion. After weaning, male Wistar rats were submitted to a normal-protein-diet (17%-protein, NP) or low-protein-diet (6%-protein, LP) for 60 days. Pancreatic islets isolated hydrogen peroxide (H2 O2 ), oxidized (GSSG) (GSH) glutathione content, CuZn-superoxide dismutase (SOD1), peroxidase (GPx1) catalase (CAT) gene expression, as well...

10.1002/jcp.25908 article EN Journal of Cellular Physiology 2017-03-31

The fruit bat Artibeus lituratus absorbs large amounts of glucose in short periods time and maintains normoglycemia even after a prolonged starvation period. Based on these data, we aimed to investigate various aspects related with homeostasis analyzing: blood insulin levels, intraperitoneal tolerance tests (ipGTT ipITT), glucose-stimulated secretion (2.8, 5.6 or 8.3 mmol/L glucose) pancreas fragments, cellular distribution beta cells, the amount pAkt/Akt pectoral muscle liver. Blood levels...

10.1016/j.cbpa.2010.05.016 article EN publisher-specific-oa Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology 2010-06-09

Nutrient restriction during the early stages of life usually leads to alterations in glucose homeostasis, mainly insulin secretion and sensitivity, increasing risk metabolic disorders adulthood. Despite growing evidence regarding importance clearance homeostasis health disease, no information exists about this process malnourished animals. Thus, present study, we aimed determine effect a nutrient-restricted diet on using model which 30-d-old C57BL/6 mice were exposed protein-restricted for...

10.1017/s0007114514001238 article EN British Journal Of Nutrition 2014-07-18

Introduction Endurance training improves peripheral insulin sensitivity in the liver and skeletal muscle, but mechanism for this effect is poorly understood. Recently, it was proposed that clearance plays a major role both glucose homeostasis sensitivity. Therefore, our goal to determine by which endurance how regulates mice. Methods Mice were treadmill-trained 4 weeks at 70–80% of maximal oxygen consumption (VO2 max) 60 min, 5 days week. The tolerance resistance determined using an IPGTT...

10.1371/journal.pone.0118809 article EN cc-by PLoS ONE 2015-03-30

The aim of the study was to investigate different B-cell responses after a glucagon stimulation test (GST) versus mixed meal tolerance (MMTT).We conducted GST and MMTT in 10 healthy people (aged 25-40 years) measured C-peptide, gastric inhibitory peptide (GIP) glucagon-like peptide-1 (GLP-1) at time points administration 1 mg i.v. for or liquid MMTT.The stimulated C-peptide showed mean increase 147.1%, whereas 99.82% (Δincrease = 47.2%). Maximum level reached with greater than that obtained...

10.1002/dmrr.2899 article EN Diabetes/Metabolism Research and Reviews 2017-05-09

Introduction: Adolescent pregnancy is considered a public health problem and the school, together with PSE Nurses, committed to developing educational assistance actions, geared needs particularities of this age group.Review: This qualitative literature review.The study subjects were adolescents aged 10 19 years enrolled in schools municipality metropolitan region Salvador-Ba.Discussion: Health education must be developed partnership family professionals, as proposal reduce rate teenage...

10.31533/pubsaude4.a094 article EN cc-by Pubsaúde 2020-01-01

Syzygium cumini (L.) Skeels (Myrtaceae) has been traditionally used to treat of metabolic disorders, especially diabetes mellitus. Although there are many studies extracts from seed and fruit pulp, the works with leaves scarce. As is considerable interest in bioactive compounds syndrome its clustered risk factors, we sought characterize effects hydroethanolic extract S. (HESc) on lean monosodium L‐glutamate(MSG)‐induced obese rats. At 60 days age, both groups were randomly assigned receive...

10.1096/fasebj.30.1_supplement.692.8 article EN The FASEB Journal 2016-04-01

Synthetic glucocorticoids (GCs) are pontent and widely used anti‐inflammatory immunosuppressant agents. However, prolonged or high‐dose usage of GCs promote several side effects, especially on glucose lipid metabolism. In spite the abovementioned factors, there is scanty data differential impact distinct synthetic GC metabolic targets, particularly glycolipidic homeostasis. Thus, this work aimed to assess alterations caused by subchronic treatment with prednisone in comparison acute...

10.1096/fasebj.31.1_supplement.673.6 article EN The FASEB Journal 2017-04-01
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