A5083953703- Head and Neck Cancer Studies
- Reconstructive Surgery and Microvascular Techniques
- Tracheal and airway disorders
- Head and Neck Surgical Oncology
- Dysphagia Assessment and Management
- Voice and Speech Disorders
- Salivary Gland Tumors Diagnosis and Treatment
- Sinusitis and nasal conditions
- Ear and Head Tumors
- Nasal Surgery and Airway Studies
- Nanoplatforms for cancer theranostics
- Allergic Rhinitis and Sensitization
- Nerve Injury and Rehabilitation
- Airway Management and Intubation Techniques
- Reconstructive Facial Surgery Techniques
- Photodynamic Therapy Research Studies
- Oral and Maxillofacial Pathology
- Pancreatic function and diabetes
- Cleft Lip and Palate Research
- Interpreting and Communication in Healthcare
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Mechanisms and Therapy
- Trauma Management and Diagnosis
- Cancer Research and Treatments
- Bone Tumor Diagnosis and Treatments
Massachusetts Eye and Ear Infirmary
2017-2024
Harvard University
2017-2024
Changzhi Medical College
2024
Western University
2014-2021
University of Michigan
2020-2021
University of Toronto
2021
University of Alberta
2011-2021
Brigham and Women's Hospital
2020
Johns Hopkins University
2013-2017
Johns Hopkins Medicine
2013-2017
Background Previous studies have identified subdomains of the 22‐item Sino‐Nasal Outcome Test (SNOT‐22), reflecting distinct and largely independent categories chronic rhinosinusitis (CRS) symptoms. However, no study has validated subdomain structure SNOT‐22. This aims to validate existence underlying symptom SNOT‐22 using confirmatory factor analysis (CFA) develop a model that practitioners researchers can use describe CRS symptomatology. Methods A total 800 patients with were included into...
6010 Background: Prediction of minimal residual disease (MRD) following surgery, and thus the need for adjuvant therapy, is currently based on clinicopathologic risk factors which have poor individual prognostic capacity. We previously reported that MRD detection by ctHPVDNA droplet digital (dd)PCR as early post-operative day (POD) 1 predictive recurrence in stage I-II HPV+HNSCC patients. Here, we applied a significantly more sensitive custom whole genome hybrid-capture-based next generation...
Objective Previous observational studies suggest higher rates of vestibular dysfunction among patients with type 2 diabetes mellitus (DM) compared those without diabetes. This study aims to functionally localize in adults DM. Study Design Prospective cohort study. Setting Tertiary academic medical center. Subjects and Methods Adults 50 years age older ≥10‐year history DM were recruited (December 2011–February 2013, n = 25). Vestibular function was assessed by cervical ocular...
Objective To investigate intraoperative nerve monitoring (IONM) use among thyroid surgeons. Methods A 25‐question survey was used to assess attitudes regarding IONM use. Surveys were sent surgeons registered the American Academy of Otolaryngology–Head and Neck Surgery, International Association Endocrine Surgeons, Head Society. Results Among 1,015 respondents, 83% reported using (65.1% always 18.1% reporting selective use). For users, a majority for reoperative cases (95.1%) in with...
The optimal reconstruction of total glossectomy defects with or without laryngectomy is controversial. Various pedicled and free tissue flaps have been advocated, but long-term data on functional outcomes are not available to date.To compare various defect reconstructive techniques used by multiple institutions identify factors that may lead improved speech swallowing function.A multi-institutional, retrospective review electronic medical records patients undergoing at 8 participating...
Objective To investigate the frequency and outcomes of elective neck dissection (END) for adenoid cystic carcinoma (ACC) head neck. Methods The National Cancer Database was queried a cohort study patients with ACC major salivary glands, nasal cavity/nasopharynx, hard/soft palate, tongue, floor mouth, larynx, oral cavity who underwent primary surgical resection from 2004 to 2014. Multivariable logistic regression used identify predictors END occult nodal metastasis. Overall survival (OS)...
The impact of close surgical margins on oncologic outcomes in HPV-related oropharyngeal squamous cell carcinoma (HPV + OPSCC) is unclear.Retrospective case series including patients undergoing single modality transoral robotic surgery (TORS) for HPV OPSCC at three academic medical centers from 2010 to 2019. Outcomes were compared between with (<1 mm or requiring re-resection) and clear using the Kaplan-Meier method.Ninety-nine included (median follow-up 21 months, range 6-121). Final 22...
To investigate the use of an algorithm for rapid discharge after transoral robotic surgery (TORS) and its effect on postoperative complications.Retrospective cohort study.A retrospective analysis TORS cases from September 2009 to February 2013 was conducted. The patient tumor characteristics length stay (LOS) complications were analyzed.A total 91 patients included; 79 underwent malignancy 12 a benign process. mean LOS 1.51 days (range, 1-5 days) with median 1 day. time initiation oral diet...
To determine the efficacy of combined continuous sorafenib therapy and drug-eluting bead (DEB) transarterial chemoembolization (TACE) in patients with unresectable hepatocellular carcinoma (HCC).This study was conducted accordance principles Declaration Helsinki, all provided written informed consent prior to enrollment. Inclusion criteria included HCC, a treatment naïve status, an Eastern Cooperative Oncology Group score 0-1, Child-Pugh A-B7. Continuous (400 mg twice daily) started 1 week...
Objective We sought to establish the significance of querying chronic rhinosinusitis (CRS) patients about their past CRS‐related oral antibiotic and corticosteroid usage by determining association between these metrics patients’ quality life (QoL). Study Design Cross‐sectional study. Methods A total 157 with CRS were prospectively recruited. CRS‐specific QoL was measured using 22‐item Sinonasal Outcome Test (SNOT‐22). General health‐related EuroQoL five‐dimensional questionnaire visual...
Many options for free tissue transfer have been described head and neck reconstruction. Although functional outcomes remain paramount, aesthetic considerations such as color match can be equally consequential patient quality of life. It is important to understand differences in based on flap donor site
Objectives To develop a novel sensor capable of dynamically analyzing the force exerted during suspension microlaryngoscopy and to examine relationship between postoperative tongue complications. Study Design Prospective observational study. Setting Academic tertiary care center. Methods The laryngeal is designed for use microphonosurgery. Prospectively enrolled patients completed pre‐ surveys assess development tongue‐related symptoms (dysgeusia, pain, paresthesia, paresis) or dysphagia...
Objective Assess the feasibility of a novel robotic platform for use in microvascular surgery. Study Design Prospective study. Setting Robotics laboratory. Methods The Robotic ENT (Ear, Nose, and Throat) Microsurgery System (REMS) (Galen Robotics, Inc., Sunnyvale, CA) is arm that stabilizes surgeon's instrument, allowing precise, tremor‐free movement. Six naïve medical students one expert performed anastomosis chicken ischiatic artery, with without REMS. Trials were blindly graded by seven...
Objectives Microsurgical techniques are essential for vessel anastomosis in free flap reconstructive surgery. However, teaching these skills intraoperatively is difficult. The chicken thigh microvascular model a high‐fidelity that has been previously validated to differentiate between skill levels of surgeons. This study aims determine if this objectively improves microsurgical skills. Study Design Validation Methods Thirteen residents were given tutorial on and asked perform anastomoses the...
Coronavirus disease 2019 (COVID-19) has significantly impacted endonasal surgery, and recent experimentation demonstrated that sinonasal drilling cautery have significant propensity for airborne particulate generation immediately adjacent to the surgical field. In present investigation, we assessed nasopharyngeal suctioning as a mitigation strategy decrease spread during simulated activity.Airborne in 1-µm 10-µm range was quantified with an optical particle sizer real-time...
To identify the most frequently asked questions regarding "laryngectomy" through an assessment of online search data.Google Search data based on term were analyzed using Google Trends and Response. The common People Also Ask (PAA) identified classified by concept. Each website linked to its respective PAA question was rated for understandability, ease reading, reading grade level.Search popularity remained stable between 2017 2022. popular themes post-laryngectomy speech, laryngectomy...