A5036717374- Sinusitis and nasal conditions
- Allergic Rhinitis and Sensitization
- Nasal Surgery and Airway Studies
- Asthma and respiratory diseases
- Olfactory and Sensory Function Studies
- Head and Neck Surgical Oncology
- Meningioma and schwannoma management
- Spinal Fractures and Fixation Techniques
- Patient-Provider Communication in Healthcare
- Respiratory and Cough-Related Research
- Neuroendocrine regulation and behavior
- Ear Surgery and Otitis Media
- Evolutionary Psychology and Human Behavior
- Dental Research and COVID-19
- Pharmaceutical Practices and Patient Outcomes
- Pituitary Gland Disorders and Treatments
- Palliative Care and End-of-Life Issues
- Political Economy and Marxism
- Innovations in Medical Education
- Housing, Finance, and Neoliberalism
- Spine and Intervertebral Disc Pathology
- COVID-19 and Mental Health
- Healthcare Quality and Management
- Cleft Lip and Palate Research
- Facial Nerve Paralysis Treatment and Research
University of Cincinnati Medical Center
2020-2025
The Royal Melbourne Hospital
2020-2025
University of Utah
2024
Kaiser Permanente
2024
University of Cincinnati
2021-2023
Sabin Vaccine Institute
2020-2023
Melbourne Health
2022
Sidmouth Hospital
2020-2021
Stanford University
2019-2021
Triological Society
2020-2021
Abstract The coronavirus SARS-CoV-2 is the causative agent of ongoing severe acute respiratory disease pandemic COVID-19. Tissue and cellular tropism one key to understanding pathogenesis SARS-CoV-2. We investigate expression subcellular localization receptor, angiotensin-converting enzyme 2 (ACE2), within upper (nasal) lower (pulmonary) tracts human donors using a diverse panel banked tissues. Here, we report our discovery that ACE2 receptor protein robustly localizes motile cilia airway...
To determine whether introducing a rapid test for meticillin resistant Staphylococcus aureus (MRSA) screening leads to reduction in MRSA acquisition on hospital general wards.Cluster randomised crossover trial.Medical, surgical, elderly care, and oncology wards of London teaching two sites.MRSA rate (proportion patients negative who became positive).All admitted the study were admission screened discharge.Rapid polymerase chain reaction based compared with conventional culture.Of 9608 wards,...
Background Previous studies have identified subdomains of the 22‐item Sino‐Nasal Outcome Test (SNOT‐22), reflecting distinct and largely independent categories chronic rhinosinusitis (CRS) symptoms. However, no study has validated subdomain structure SNOT‐22. This aims to validate existence underlying symptom SNOT‐22 using confirmatory factor analysis (CFA) develop a model that practitioners researchers can use describe CRS symptomatology. Methods A total 800 patients with were included into...
Background: The degree to which different sinonasal symptoms contribute the overall quality of life (QOL) detriment in chronic rhinosinusitis (CRS) patients remains unknown. In this study we sought characterize effect CRS on general health-related QOL patients. Methodology: We performed a prospective cross-sectional 131 adult with CRS. Sinonasal were evaluated using 22-item Outcomes Test (SNOT-22) and was EuroQol 5-Dimensional survey (EQ5D) visual analog scale (EQ5D-VAS). Health utility...
Abstract Objective To analyze the accuracy of ChatGPT‐generated responses to common rhinologic patient questions. Methods Ten questions from rhinology patients were compiled by a panel 4 fellowship‐trained surgeons based on clinical experience. This (Panel 1) developed consensus “expert” each question. Questions individually posed ChatGPT (version 3.5) and its recorded. graded Panel 1 scale 0 (incorrect) 3 (correct exceeding quality expert responses). A 2nd was given question asked guess...
Objective To determine the minimal clinically important difference (MCID) of 22‐item Sinonasal Outcome Test (SNOT‐22) in individuals undergoing medical management for their chronic rhinosinusitis (CRS). Design Prospective observational study. Setting Academic, tertiary care centre. Participants A total 247 adults CRS. Main outcome measure At enrolment, participants completed a SNOT‐22. subsequent follow‐up visit, 2‐12 months after also follow‐up, rated change sinus symptoms and general...
BACKGROUND:In this study, we identified key discrete clinical and technical factors that may correlate with primary reconstructive success in endoscopic skull base surgery (ESBS). METHODS: ESBS cases intraoperative cerebrospinal fluid (CSF) leaks at four tertiary academic rhinology programs were retrospectively reviewed. Logistic regression associated surgical outcomes by defect subsite (anterior cranial fossa [ACF], suprasellar [SS], purely sellar, posterior [PCF]). RESULTS: Of 706 patients...
Previous work has shown patients commonly misuse adrenaline autoinjectors (AAI). It is unclear whether this due to inadequate training, or poor device design. We undertook a prospective randomized controlled trial evaluate ability administer using different AAI devices.We allocated mothers of food-allergic children prescribed an for the first time Anapen EpiPen computer-generated randomization list, with optimal training according manufacturer's instructions. After one year, participants...
The incidence of Bell's palsy (BP) is elevated in the late phases pregnancy. Controversy exists as to whether pregnancy a risk factor for worse outcomes BP, and such are result factors intrinsic or tendency withhold medical therapy this cohort.Long-term facial function cases pregnancy-associated BP (PABP) were compared against affecting nonpregnant adult women child-bearing age by blinded expert using electronic clinician-graded scale (eFACE) grading system.Fifty-one 58...
To determine the association between frequency of acute chronic rhinosinusitis (CRS) exacerbations (AECRS) and degree asthma control in asthmatic CRS patients.Cross-sectional study.We prospectively recruited 108 patients as participants. Asthma was assessed using Control Test (ACT). The AECRS three previously described indirect metrics for AECRS: patient-reported sinus infections, CRS-related antibiotics use, oral corticosteroids use last 3 months. symptom severity measured 22-item Sinonasal...
Responsiveness and minimal clinically important difference for the EQ-5D in chronic rhinosinusitis* Background: The 5-dimensional EuroQol questionnaire (EQ-5D) is validated to measure general health-related quality of life (QOL).Our objective was determine responsiveness (MCID) health utility value (EQ-5D HUV) visual analog scale VAS) rhinosinusitis (CRS).Methods: 203 adults undergoing medical management CRS were prospectively recruited.General QOL (using HUV CRS-specific 22-item Sinonasal...
ABSTRACT Background There is limited consensus on management protocols and practice patterns following endoscopic skull base surgery (ESBS). Methods An online‐based survey focusing ESBS was anonymously distributed to the American Rhinologic Society, North Skull Base Head Neck Society Section membership. Results A total of 130 surgeons (81.5% in academic positions) completed survey. Regarding reconstructive materials, 36.9% always used autologous as opposed synthetic with variation specific...
Objectives/Goals: Academic research centers struggle to recruit and retain a diverse, competent clinical translational science (CTS) workforce. The professional career pathway is particularly underrecognized among undergraduates, despite offering multiple opportunities. Methods/Study Population: To address these challenges, two undergraduate outreach programs were developed. First, an certificate program in CTS (UC-CTS) was designed equip students with the skills knowledge needed enter...
Temperature-controlled radiofrequency (TCRF) ablation of the posterior nasal nerve has been shown to improve chronic rhinitis (CR) symptoms and quality life (QoL). This study assesses durability TCRF's effectiveness safety 3 years post-procedure in patients with perennial allergic CR nonallergic CR. prospective, multicenter, single-blinded, randomized controlled trial included a sham control arm long-term follow-up. Analysis combined from active treatment crossover arms. Outcomes include...
Background.Nurses in primary care, who see a large proportion of the population, are well placed to discuss weight with patients and offer management advice. Interventions promote loss have shown that there effective ways making small changes for patients.