A5036001842- Head and Neck Surgical Oncology
- Head and Neck Cancer Studies
- Tracheal and airway disorders
- Salivary Gland Tumors Diagnosis and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Sinusitis and nasal conditions
- Thyroid Cancer Diagnosis and Treatment
- Meningioma and schwannoma management
- Infection Control and Ventilation
- Ear and Head Tumors
- Pituitary Gland Disorders and Treatments
- Voice and Speech Disorders
- Thyroid and Parathyroid Surgery
- COVID-19 and healthcare impacts
- Parathyroid Disorders and Treatments
- Head and Neck Anomalies
- Surgical site infection prevention
- Tumors and Oncological Cases
- Reconstructive Facial Surgery Techniques
- Cancer Diagnosis and Treatment
- Facial Nerve Paralysis Treatment and Research
- Genetic Syndromes and Imprinting
- Cancer survivorship and care
- Obstructive Sleep Apnea Research
- Nasal Surgery and Airway Studies
Penn State Milton S. Hershey Medical Center
2016-2025
Pennsylvania State University
2016-2025
Semmes Murphey Foundation
2021-2024
University of Tennessee Health Science Center
2024
Harvard University
2015-2024
Temple University
2024
American Academy of Otolaryngology — Head and Neck Surgery
2024
Indraprastha Apollo Hospitals
2016-2023
University of Arkansas for Medical Sciences
2022
Apollo Hospitals
2022
Head and neck cancers (HNC) are a biologically diverse set of that responsible for over 660,000 new diagnoses each year. Current therapies HNC require comprehensive, multimodal approach encompassing resection, radiation therapy, systemic therapy. With an increased understanding the mechanisms behind HNC, there has been growing interest in more accurate prognostic indicators disease, effective post-treatment surveillance, individualized treatments. This chapter will highlight commonly used...
Abstract Current nucleic acid delivery methods have not achieved efficient, non‐toxic of miRNAs with tumor‐specific selectivity. In this study, a new system based on light‐inducible gold–silver–gold, core–shell–shell (CSS) nanoparticles is presented. This delivers small therapeutics precise spatiotemporal control, demonstrating the potential for achieving selectivity and efficient miRNA mimics. The particles leverage photothermal heating metal due to local surface plasmonic resonance...
Abstract Objective The role of estrogen in developing thyroid malignancy is poorly understood. Epidemiological studies have shown exogenous associated with increased risk females. Still, no to date investigated this association among biological males undergoing hormone therapy. Study Design Retrospective cohort study. Setting TriNetX Research Network. Methods Biologically male patients prescribed at least 5 years follow‐up were queried from the database. Rates diagnosis malignant neoplasm...
ABSTRACT Carcinoma ex pleomorphic adenomas are rare malignant tumors of the salivary glands, primarily seen in older adults. They originate from benign adenomas, aggressive, and have poorer prognosis. This case documents an unusual presentation a massive carcinoma adenoma.
Abstract Objective The objective of this study is to examine the risk hypocalcemia after thyroidectomy in patients taking histamine‐2 receptor antagonists. Study Design Retrospective cohort study. Setting Multicenter, single database. Methods Thirty‐four thousand two hundred eighteen treated with total from 2011 2022 were identified via TriNetX Research Network. We compared incidence transient (0‐1 month and 1‐6 months following thyroidectomy) permanent (6‐12 postthyroidectomy without H2...
ABSTRACT Objective The ease of access online videos and the popularity visual learning have made YouTube a popular educational resource. We analyzed utility for graduate medical education about free flap surgery using cross‐sectional study design. Methods Using phrases “free surgery” head neck,” inclusion were identified. Videos by surgeons Modified DISCERN, Global Quality Score (GQS), JAMA Benchmark metrics video quality, value, transparency, respectively. Statistical analysis metadata...
ABSTRACT Objective Ultrasound (US) is a well‐established imaging modality for the evaluation of head and neck anatomy. The Butterfly iQ handheld ultrasound device that uses semiconductor silicon chip array (capacitive micromachined transducers, CMUT) instead piezoelectric crystals used by traditional ultrasounds (TUS), but its accuracy has not been investigated with respect to salivary gland associated transcutaneous procedures. We aimed perform pilot cadaver study determine utility fidelity...
Abstract Objective In 2020, the Food and Drug Administration (FDA) approved Merck's GARDASIL 9 for prevention of certain human papillomavirus (HPV)‐related head neck cancer. This study characterizes sentiment themes HPV vaccination online discourse surrounding 2020 FDA recommendation. Study Design Retrospective cohort. Setting Data from 2018 to 2022: Reddit, Teen VaxView (Centers Disease Control Prevention), Google Trends. Methods Online public was assessed by searching Reddit user submitted...
Abstract Background A prior study reported that over half of patients with HNSCC initiated PORT after 6 weeks from surgery during 2006–2014. In 2022, the CoC released a quality metric for to initiate within weeks. This provides an update on time in recent years. Methods The NCDB and TriNetX Research Network were queried identify who received 2015–2019 2015–2021, respectively. Treatment delay was defined as initiating beyond surgery. Results NCDB, delayed 62% patients. Predictors included age...
There is an increasing incidence of head and neck cancers that present as masses in a nonsmoking nondrinking population. These can be confused with benign cystic masses. The purpose this study was to determine imaging criteria differentiate lateral cysts from malignant adenopathy.A retrospective analysis patients who underwent contrast-enhanced CT between July 2003 2011 performed. Patients were diagnosed either branchial cleft cyst or pharyngeal squamous cell cancer. Each examination...
To characterize our experience with the surgical management of anterior skull base malignancy, and to propose an algorithm for approach malignancies.Retrospective review.Academic cranial center.Sixty-seven patients who underwent resection paranasal sinus or malignancy endoscopic, cranioendoscopic, traditional craniofacial approach.Complications, recurrence, survival.There were 48 males 19 females, ranging from 6 88 years old. There three groups: endonasal endoscopic (n = 10),...
<h3>Importance</h3> Although a few studies have shown that mental health disorders (MHDs) are strongly associated with the 5-year survival and recurrence rates in patients head neck cancer (HNC), none been replicated large-scale study. <h3>Objective</h3> To describe prevalence of MHDs HNC potential associations using large insurance claims database. <h3>Design, Setting, Participants</h3> This retrospective cohort study assessed data queried from MarketScan database January 1, 2005, through...
Abstract Objective We analyzed the pooled case‐control data from International Head and Neck Cancer Epidemiology (INHANCE) consortium to compare cigarette smoking alcohol consumption risk factors for head neck cancer between less developed more countries. Subjects Methods The location of each study was categorized as either a or country. compared overall specific anatomic subsites associated with consumption. Additionally, age sex distribution categories compared. Results odds ratios sites...
The incidence of thyroid cancer in the United States has increased rapidly and Pennsylvania is state with highest rate country, although factors driving this increase are unknown. Moreover, it remains unclear whether represents a true disease or result overdiagnosis.To compare tumor characteristics rest gain insight into influencing cancer.In population-based study, data on from Surveillance Epidemiology End Results 9 (SEER-9) registry Cancer Registry (PCR) 1985 through 2009 were collected...
To evaluate surgical site infections (SSI) after pedicled reconstruction in head and neck surgery.Records of patients with flap reconstructions between 2009 2014 at Massachusetts Eye Ear were reviewed. Onset SSI or fistula ≤30 days postoperatively was noted. A free cohort reviewed for comparison.Two hundred eight performed cancer (83%), osteoradionecrosis (7%), other reasons (10%). Most (72%) cases clean-contaminated American Society Anesthesiologists classification 3 higher (73%); 63% had...
Importance Despite access to routine laboratory evaluation, primary hyperparathyroidism (PHP) remains underdiagnosed and undertreated. Objective To determine the consequences associated with missed diagnoses prolonged time diagnosis treatment of PHP. Design, Setting, Participants This is a retrospective cohort study patients older than 40 years 2 instances hypercalcemia during 2010 2020 3 follow-up. Patients were recruited from 63 health care organizations in TriNetX Research Network. Data...
IMPORTANCE To describe clinical parameters for the management of pediatric patient with nasal anatomical deformity or functional impairment. OBJECTIVES review authors' experience corrective surgery in patients and make recommendations regarding indications surgical techniques. DESIGN, SETTING, AND PARTICIPANTS A retrospective medical chart was performed all male younger than 16 years female 14 seen by senior author (F.G.F.) at a tertiary referral center between August 1996 2012. The database...