A5100452272- Adolescent and Pediatric Healthcare
- Viral Infections and Outbreaks Research
- Health Systems, Economic Evaluations, Quality of Life
- Child Nutrition and Feeding Issues
- Hepatitis B Virus Studies
- Mathematical and Theoretical Epidemiology and Ecology Models
- Reproductive Health and Contraception
- Autism Spectrum Disorder Research
- Cardiac Imaging and Diagnostics
- Nerve injury and regeneration
- Disaster Response and Management
- Fungal Biology and Applications
- Viral Infections and Vectors
- Opioid Use Disorder Treatment
- Maternal Mental Health During Pregnancy and Postpartum
- Injury Epidemiology and Prevention
- Traffic and Road Safety
- Orthopedic Surgery and Rehabilitation
- Infrared Thermography in Medicine
- Mathematical Biology Tumor Growth
- Retinal Diseases and Treatments
- Child and Adolescent Psychosocial and Emotional Development
- Liver Disease Diagnosis and Treatment
- Cytokine Signaling Pathways and Interactions
- Iron Metabolism and Disorders
Daping Hospital
2009-2025
Army Medical University
2012-2025
Pennsylvania State University
2015-2024
Penn State Milton S. Hershey Medical Center
2014-2024
Dalian Medical University
2024
Chongqing Medical University
2012-2024
Second Affiliated Hospital of Chongqing Medical University
2024
University of Science and Technology Beijing
2021-2024
Chinese Academy of Sciences
2024
University of Chinese Academy of Sciences
2024
The concept of "ligand bias" at G protein coupled receptors has been introduced to describe ligands which preferentially stimulate one intracellular signaling pathway over another. There is growing interest in developing biased receptor yield safer, better tolerated, and more efficacious drugs. classical μ opioid morphine elicited increased efficacy duration analgesic response with reduced side effects β-arrestin-2 knockout mice compared wild-type mice, suggesting that agonists would be...
Patients presenting to the emergency department (ED) with chest pain whose evaluation for ischemia demonstrates no abnormalities receive further functional or anatomical studies coronary artery disease; however, comparative evidence various strategies is lacking and multiple testing options exist.To compare pathways based on their association downstream testing, interventions, outcomes patients in EDs.Retrospective analysis of health insurance claims data a national sample privately insured...
Diseases of immune dysregulation are associated with an increased risk viral infections, some which may be preventable. To date, there very limited data on the incidence and influenza related complications in patients inflammatory bowel disease (IBD). Furthermore, impact immunosuppressive medications that is unclear. Therefore, aim this study was to estimate severity infections IBD patients. In addition, we looked specifically at effect risk.Using MarketScan Database (January 2008 December...
Stromal cell-derived factor-1 (SDF-1) is a potent chemokine for bone marrow-derived stromal stem cells (BMSCs) that express CXCR4, the receptor SDF-1. SDF-1 considered to play an important role in trafficking of BMSCs. We investigated contribution recruitment BMSCs wound area and its promotion repair neovascularization. were pretreated with or without anti-CXCR4 blocking antibody combined CM-DiI label, injected via tail vein into mice full-thickness skin wounds on dorsum. Simultaneously,...
Iron deficiency anemia during pregnancy is a significant public health problem in sub-Saharan Africa (SSA) and associated with serious adverse outcomes. Although it recommended that all women receive iron supplementation pregnancy, little research has been conducted to measure overall compliance this recommendation or variation across SSA countries.
Objective Using a large U.S. claims database (MarketScan), we investigated the controversy surrounding role of statins in Parkinson's disease (PD). Methods We performed retrospective case-control analysis. First, identified 2322 incident PD cases having minimum 2.5 years continuous enrollment prior to earliest diagnosis code or prescription antiparkinson medication. A total controls were then matched individually by age, gender, and follow-up window explore relationship statin use with PD....
In this paper, we explore an impulsive stochastic infected predator-prey system with Lévy jumps and delays. The main aim of paper is to investigate the effects time delays impulse interference on dynamics model. First, prove some properties subsystem system. Second, in view comparison theorem limit superior theory, obtain sufficient conditions for extinction Furthermore, persistence mean also investigated by using theory differential equations (ISDE) delay (DDE). Finally, carry out...
Optimal surgical management of anterior shoulder instability remains controversial. There is a need to assess the most recent trends for primary and revision stabilization surgery using national database significantly larger than those previously utilized.Most procedures are performed arthroscopically. Examining procedures, we hypothesized that open would result in decreased stabilizations compared with arthroscopic be Bankart or bone transfer regardless index procedure technique.Descriptive...
<h3>Importance</h3> Restless legs syndrome (RLS) is a common neurologic disorder that has been previously found to be associated with higher odds of suicidal ideation. In the context increasing suicide rate in United States, evidence regarding association between RLS and risk self-harm limited. <h3>Objective</h3> To investigate self-harm. <h3>Design, Setting, Participants</h3> This cohort study was performed using Truven Health MarketScan national claims data from 2006 2014; baseline were...
Cell transplantation is an effective strategy to improve the repair effect of nerve guide conduits (NGCs). However, problems such as low loading efficiency and cell anoikis undermine outcomes. Microcarriers are efficient 3D culture scaffolds, which can also prevent by providing substrate for adhesion during transplantation. Here, we demonstrate first time microcarrier-based in peripheral repair. We prepared macroporous chitosan microcarriers (CSMCs) emulsion-phase separation method, then...
Background: Reduced arm swing amplitude, symmetry, and coordination during gait have been reported in Parkinson's disease (PD), but the relationship between dopaminergic depletion these upper limb changes remains unclear. Objective: We aimed