A5072132429- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Liver Diseases and Immunity
- Hepatocellular Carcinoma Treatment and Prognosis
- Organ Transplantation Techniques and Outcomes
- Gastrointestinal Bleeding Diagnosis and Treatment
- Drug-Induced Hepatotoxicity and Protection
- Renal Transplantation Outcomes and Treatments
- Clostridium difficile and Clostridium perfringens research
- Gastroesophageal reflux and treatments
- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- Gastrointestinal disorders and treatments
- HIV/AIDS drug development and treatment
- Esophageal and GI Pathology
- Gallbladder and Bile Duct Disorders
- Colorectal Cancer Screening and Detection
- Genetic and Kidney Cyst Diseases
- Abdominal vascular conditions and treatments
- Cancer, Lipids, and Metabolism
- Hepatitis Viruses Studies and Epidemiology
- Diet, Metabolism, and Disease
- Poverty, Education, and Child Welfare
Philadelphia VA Medical Center
2024
University of Pennsylvania
2024
Penn State Milton S. Hershey Medical Center
2012-2022
Pennsylvania State University
2005-2022
Stockport NHS Foundation Trust
2021
The University of Western Australia
1984-2020
Pathwest Laboratory Medicine
2020
National Institute on Aging
2020
Information Management Services
2018
Hershey (United States)
2007-2013
<h3>Importance</h3> Direct-acting antiviral (DAA) drugs are highly effective in curing hepatitis C virus (HCV) infection. Previous simulations showed extended life as a key health advantage of DAA drugs, but real-world evidence on the association between treatment and reduced mortality is limited. <h3>Objectives</h3> To examine with among Medicare beneficiaries C. <h3>Design, Setting, Participants</h3> This cohort study used claims data who sought care for first time January 1, 2014,...
Hepatitis C is a common chronic infection. Nonsteroidal anti-inflammatory drugs are commonly ingested both over-the-counter and by prescription. This case report describes three cases where ibuprofen use leads to marked rise in hepatic transaminases with one repeating on rechallenge. These support the recommendation of acetaminophen over nonsteroidal drug patients hepatitis C.
Bacillary peliosis hepatis is an uncommon but well recognized disease due to disseminated Bartonella infections occurring predominantly in immunocompromised individuals infected with human immunodeficiency virus, type 1. A similar condition the absence of infection when described organ transplant patients was felt be secondary azathioprine and/or cyclosporine.Herein, we report first case bacillary systemic henselae a patient after kidney transplant. The presented severe anemia, persistent...
End stage liver disease (ESLD) is associated with significant thrombotic complications. In this study, we attempted to determine if patients ESLD, due oncologic or autoimmune diseases, are susceptible thrombosis a greater extent than ESLD other causes. retrospective analyzed the UNOS database incidence of complications in orthotopic transplant (OLT) recipients and conditions. Between 2000 2012, 65,646 OLTs were performed. We found 4,247 cases preoperative portal vein (PVT) 1,233...
<h3>Importance</h3> Direct-acting antiviral (DAA) medications are highly effective in treating hepatitis C virus (HCV) infection. However, use of DAAs rural and underserved areas is low owing to limited access specialist physicians with experience care HCV Project ECHO (Extension for Community Healthcare Outcomes) a distance education model that trains primary improve populations complex diseases such as Evidence on whether associated increased DAA limited. <h3>Objective</h3> To examine the...
The aim of this study was to answer the question: How often does ultrasound change liver biopsy position, when a percussion technique is applied, because intervening structures? A secondary objective compare performance hepatologist radiology technician demonstrate safety self-training technique.One hundred sixty-five consecutive outpatient biopsies were studied. Using standard technique, site chosen and marked. Ultrasound applied marked site. An adequate determined be one without structure...
Objectives: The aim of this study was to answer the question: How often does ultrasound change liver biopsy position, when a percussion technique is applied, because intervening structures? A secondary objective compare performance hepatologist radiology technician demonstrate safety self-training technique. Methods: One hundred sixty-five consecutive outpatient biopsies were studied. Using standard technique, site chosen and marked. Ultrasound applied marked site. An adequate determined be...
New hepatitis C virus (HCV) drugs-direct-acting antivirals (DAAs)-are highly effective but costly, which raises a concern about limited access to DAAs by vulnerable populations. Previous studies of disparities in DAA use across patient groups showed mixed results, their generalizability was due using data from commercial insurers or 2014 only-the first year were available. Disparities national cohort the years when more available is unknown.To examine whether race/ethnicity and socioeconomic...
Significantly worse survival has been reported in patients with hepatopulmonary syndrome (HPS) and partial pressure of arterial oxygen (PaO2) <45 mmHg undergoing liver transplantation. Long-term pre- post-transplant outcomes based on degree hypoxaemia were re-examined.A retrospective analysis 1,152 HPS candidates listed an approved model for end-stage disease (MELD) exception was performed. A Fine Gray competing risks utilised to evaluate pre-transplant PaO2 thresholds <45, 45 <60, ≥60 mmHg....
Chronic hepatitis C virus (HCV) infection is an important public health concern. Limited information exists on disparities in the quality of HCV care. We examine genotype or quantitative ribonucleic acid testing before and after starting treatment, screening for hepatocellular carcinoma (HCC) patients with cirrhosis.This national study included Medicare beneficiaries between 2014 2017. used bivariate probit to estimate probability receiving recommended tests treatment by patient...
Immunosuppression management in post-transplant malignancy is challenging because of a lack objective immunologic assessment tools. The ImmuKnow assay measures the ATP level from CD4 T cells, quantifying cell-mediated immunity and providing an insight into immune status transplant recipients. Its potential use patients with de novo was evaluated. Thirteen adult were divided survivors (n = 9) non-survivors 4) after treatment. Tacrolimus levels monitored before, during, group significantly...