A5052404178- Natural Antidiabetic Agents Studies
- Cholinesterase and Neurodegenerative Diseases
- Pharmaceutical and Antibiotic Environmental Impacts
- Plant Toxicity and Pharmacological Properties
- Microbial Metabolism and Applications
- Lipid metabolism and biosynthesis
- Natural product bioactivities and synthesis
- Sesquiterpenes and Asteraceae Studies
- Marine Sponges and Natural Products
- Aquatic Ecosystems and Phytoplankton Dynamics
- Essential Oils and Antimicrobial Activity
- Plant biochemistry and biosynthesis
- Phytochemistry and Biological Activities
- Herbal Medicine Research Studies
- Enzyme-mediated dye degradation
- African Botany and Ecology Studies
- Alzheimer's disease research and treatments
- Phytochemical and Pharmacological Studies
- Chromium effects and bioremediation
University of Zululand
2021-2025
The challenges of antimicrobial resistance (AMR) to human health have pushed for the discovery a new antibiotics agent from natural products. Cyanobacteria are oxygen-producing photosynthetic prokaryotes found in variety water habitats. Secondary metabolites produced by cyanobacteria survive extreme environmental stress factors, including microbial competition. This study presents antibacterial activity and mechanism crude extracts Cylindrospermum alatosporum NR125682 (A) Loriellopsis...
Despite the many current cholesterol-lowering drugs on market, persistent surge of hypercholesterolemic-related complications ignites a fascinating search for discovery novel therapeutics. This study aimed at investigating anti-hypercholesterolemic effect Bauhinia bowkeri extracts. The plant material was sequentially extracted with n-hexane, dichloromethane (DCM), and 70% ethanol. phytochemical constituents extracts were analyzed through GC-MS antioxidant activity screened against wide range...
Synthetic and untreated dyes discharged in wastewater effluents are a threat to an ecosystem. This study investigated dye degradation detoxification efficiency of crude lignin peroxidase separately obtained from the cultures Escherichia coli (LR0250096.1) Pseudomonas aeruginosa (CP031449.2). The ability degrade Malachite Green (MG), Remazol Brilliant Blue R (RBBR), Congo Red (CR), Azure B (AZ) was evaluated at different operating conditions (enzyme, dye, hydrogen peroxide concentrations; pH;...
Alzheimer's disease (AD) is the most common form of dementia and constitutes fifth leading cause mortality across globe. Available treatment modalities drugs have abysmally failed to curtail AD. This study evaluated mitigation Aβ aggregation anti-cholinesterase activities with crude extracts Ptaeroxylon obliquum Bauhinia bowkeri. Computational studies abundant phytochemicals from both plants proteins were investigated. The phytochemical composition different (hexane, DCM, ethanol) analyzed...
This study investigated anti-viral, antioxidant activity and anti-pyretic of crude extract from Artemisia afra, absinthium Pittiosporum viridflorum leaves. The extracts were prepared by maceration using aqueous, methanol dichloromethane respectively. Antiviral studies evaluated with influenza virus Fluorescence based -Neuraminidase inhibitors. Antioxidant activities determined DPPH, Nitric oxide, hydroxyl super oxide anion radicals’ Anti-pyretic rats yeast induced pyrexia. Total phenol,...
Triterpenoids have been identified as potential novel lipid‐lowering drugs for the treatment of hypertriglyceridemia. This study investigated antilipogenic and/or antilipolytic effects two triterpenoids (ARM‐2 and RA‐5) isolated from stem bark Protorhus longifolia (Benrh.) Engl. Employing a combination in silico predictions vitro assays, interactions between these key proteins involved lipogenesis lipolysis were investigated. In molecular docking analysis predicted favourable binding...
Parkia biglobosa (PB) is among the various underexploited nutritious plants. A comparative study was conducted on effect processing PB has amino and fatty acid composition. Fermented (FPB), defatted (DPB), protein isolates (PI) samples were prepared from seeds using methods, evaluated standard analytical protocols. The PI showed highest significant total non-essential acids, essential conditionally acids when compared with FPB DPB. In addition, (p < 0.05) neutral basic aromatic lowest...
Reactive oxygen species are implicated in multiple pathological conditions including erectile dysfunction. This study evaluated the vitro and vivo antioxidant potential of methanolic extracts Inula glomerata Salacia kraussii. The plant materials were pulverized extracted with methanol. phytochemical analysis, ability crude to scavenge free radicals (ABTS, DPPH, NO.) as well total phenolic flavonoid contents was investigated. In vivo, potentials (50/250 mg/kg body weight) determined an...