A5077925268- Eosinophilic Esophagitis
- Eosinophilic Disorders and Syndromes
- Gut microbiota and health
- Inflammatory Bowel Disease
- Cancer-related molecular mechanisms research
- IL-33, ST2, and ILC Pathways
- Cutaneous lymphoproliferative disorders research
- Nail Diseases and Treatments
- Microscopic Colitis
- Cancer and Skin Lesions
- Esophageal and GI Pathology
University of Colorado Denver
2021-2023
Children's Hospital Colorado
2021-2023
Cincinnati Children's Hospital Medical Center
2018-2019
University of Cincinnati
2018-2019
Abstract Molecular mechanisms driving disease course and response to therapy in ulcerative colitis (UC) are not well understood. Here, we use RNAseq define pre-treatment rectal gene expression, fecal microbiota profiles, 206 pediatric UC patients receiving standardised therapy. We validate our key findings adult paediatric cohorts of 408 participants. observe a marked suppression mitochondrial genes function across active UC, that increasing severity is notable for enrichment...
Objective: To evaluate the impact of type and dose swallowed topical steroids (STS) concurrent steroid therapy on development resolution adrenal insufficiency (AI) in pediatric eosinophilic esophagitis (EoE). Methods: We performed a retrospective case-control study EoE subjects single tertiary care center, who were treated with STS for at least 3 months diagnosed AI based peak stimulated cortisol level <18 µg/dL (500 nmol/L). Steroid forms doses, endoscopy data collected time diagnosis or...
Pilomatrixomas, also known as epithelioma calcificans, are benign tumors of hair follicle matrix cells that often mistaken for other lesions, especially cutaneous abscesses. We report an illustrative case in which a teenage girl developed red, swollen earlobe required multiple care visits and interventions until definitive diagnosis treatment were provided. Although the lesion was initially treated abscess, it continued to progress size discomfort. The correct established after imaging...