A5015306289- Inflammatory Bowel Disease
- Microscopic Colitis
- Gastrointestinal motility and disorders
- Eosinophilic Esophagitis
- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Food Allergy and Anaphylaxis Research
- Hepatitis C virus research
- Diet and metabolism studies
- Second Language Learning and Teaching
- Antibiotics Pharmacokinetics and Efficacy
- Viral Infections and Immunology Research
- Mast cells and histamine
- Clinical Nutrition and Gastroenterology
- Renal function and acid-base balance
- Vasculitis and related conditions
- Analytical Chemistry and Sensors
- EFL/ESL Teaching and Learning
- Autoimmune and Inflammatory Disorders
- Pelvic floor disorders treatments
- Multilingual Education and Policy
- Whipple's Disease and Interleukins
- Congenital gastrointestinal and neural anomalies
Gunma University
2008-2025
Gunma University Hospital
2024
University at Buffalo, State University of New York
2021
Kindai University
2021
Suzuki (Japan)
2021
Juntendo University
2021
Osaka University
2021
Nagoya University
2021
Tottori University
2021
Osaka City General Hospital
2021
Increased incidence and prevalence of pediatric inflammatory bowel disease (IBD) have been reported in Western countries. Changes the IBD Asian countries, however, remain unclear. We evaluated changes among Japanese adults children from 2004 to 2013, by using national registry data patients receiving financial aid. Data (ages 0-19 years) were compared with those young 20-39 years). In 2004, age-standardized prevalences Crohn (CD) ulcerative colitis (UC) 4.2 100,000 11.0 100,000,...
A 14-year-old girl presented with diarrhea and bloody stools was initially diagnosed infectious colitis anal fissure. The patient treated antibiotics; however, the symptoms persisted purpura appeared on patient's lower abdomen. Abdominal computed tomography indicated diffuse wall thickening of entire colon. colonoscopy revealed extensive edema, several ulcers, mucosal friability, resulting in diagnosis ulcerative colitis. Blood tests hypoalbuminemia, increased inflammatory marker levels,...
Abstract Background To assess the usefulness of rectal diameter measurement on ultrasonography as a diagnostic tool for fecal retention in children. Methods One hundred children (median age, 5.0 years), consisting 80 with functional constipation and 20 without constipation, participated study. All patients underwent physical examination that included digital examination. Forty‐five three differential planes: transection above symphysis; under ischial spine; at bladder neck. The symphysis...
Abstract Endoscopy is a central tool for diagnosing and evaluating paediatric inflammatory bowel diseases (PIBD), but too invasive to be frequently repeated in young children. Furthermore, it challenging distinguish Crohn’s disease (CD) from ulcerative colitis (UC) endoscopically. This study aimed determine biomarkers useful the diagnosis of PIBD. Cytokines, chemokines, growth factors were quantified sera 15 patients with CD or UC, at onset prior treatment, 26 age-matched controls....
Non-IgE-mediated gastrointestinal food allergies (non-IgE-GI-FAs) are one type of allergy found in neonates and infants. Few reports have defined the severity non-IgE-GI-FAs these populations.Grading scales according to extra-GI symptoms, such as poor weight gain, well systemic including fever shock, were developed retrospectively applied patients with non-IgE-GI-FAs. The relationship between both clinical laboratory findings examined.Elevation C-reactive protein levels a decrease total...
Few data on spontaneous clearance rates of cases mother-to-child transmission hepatitis C viral (HCV) infection are available in Japan. Furthermore, the treatment courses interferon-based and direct-acting antiviral agent (DAA) therapies for children also unclear. Our aim was thus to clarify long-term natural progression HCV outcomes
Influenza-associated encephalitis and encephalopathy (IAE) is a severe complication of influenza infection with high morbidity mortality. We present the case patient IL-10RA mutation who developed after infection. A 10-day-old boy recurrent fever anal fistula. Growth failure gradually became apparent. He had been treated antibiotics elemental nutrition. However, did not respond to treatments. At 11 months, he suddenly shock multiple organ failures. was then diagnosed IAE. cytokine study...
Whipple disease is a systemic chronic infection caused by <i>Tropheryma whipplei</i>. Although diarrhea common gastrointestinal symptom, diagnosis often difficult because there are no specific endoscopic findings, and the pathogen not detectable stool culture. We present female patient with who developed bloody growth retardation at age of 4 years. Colonoscopy showed mildly edematous terminal ileum marked erythema without vascular patterns throughout sigmoid colon rectum....
To evaluate prolonged esomeprazole use in Japanese pediatric patients for reflux esophagitis (RE) maintenance therapy and prevention of gastric (GU) and/or duodenal ulcers (DU) while using non-steroidal anti-inflammatory drugs (NSAIDs) or low-dose aspirin (LDA).
Abstract At present, noninvasive fibrosis markers are not available for the assessment of liver in children with chronic hepatitis C. Sixty-three C were included. Changes Wisteria floribunda agglutinin-positive Mac-2 binding protein (M2BPGi) levels evaluated l3 27 treatment-naive patients during natural course disease (median 4, range 3–6 years). treatment 36 4 (2–9) years posttreatment follow-up. There significant differences M2BPGi between control group and HCV F0 (P = 0.002) F1 <...
O-23 Effectiveness of nutritional and anti-TNF therapy in North American children with active Crohn’s disease D.Y. Lee1 *, R.N. Baldassano1, C.W. Compher2, A.M. Griffiths3, A.R. Otley4, L.G. Albenberg1, G.D. Wu2, F.D. Bushman2, J.D. Lewis2. 1Children’s Hospital Philadelphia, United States America, 2University Pennsylvania, 3The for Sick Children, Toronto, Canada, 4IWK Health Centre, Halifax, Canada
of the 3 rd International Symposium on Pediatric Inflammatory Bowel Disease S429 to oral tacrolimus.However, patient developed a colon perforation afterwards.One had maintained remission for 2 years after dose IFX was increased 10 mg/kg, and methotrexate added as combination therapy. Conclusion:The present study showed that efficacy limited in children with steroid-dependent intestinal BD.However, additional may be new option maintaining pediatric BD.
Abstract Background At present non-invasive fibrosis markers are not available for assessment of liver in children with chronic hepatitis C. Methods Sixty-three C were included. Changes Wisteria floribunda agglutinin-positive Mac-2 binding protein (M2BPGi) levels evaluated l3 27 treatment-naive patients during the observation period natural course disease (median 4, range 3-6 years). treatment 36 4 (2-9) years post-treatment follow-up. Results There significant differences M2BPGi between...