Huiyan Hu

ORCID: 0000-0002-8138-7336
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About
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Research Areas
  • Cancer-related molecular mechanisms research
  • Animal Behavior and Welfare Studies
  • Genetic and phenotypic traits in livestock
  • Metal complexes synthesis and properties
  • Synthesis of Tetrazole Derivatives
  • MicroRNA in disease regulation
  • interferon and immune responses
  • Ferroptosis and cancer prognosis
  • Inflammasome and immune disorders
  • Circular RNAs in diseases
  • RNA Interference and Gene Delivery
  • Computational Drug Discovery Methods
  • Therapeutic Uses of Natural Elements
  • Melanoma and MAPK Pathways
  • Virus-based gene therapy research
  • Herpesvirus Infections and Treatments
  • Advanced biosensing and bioanalysis techniques
  • Fluoride Effects and Removal
  • Synthesis and Characterization of Heterocyclic Compounds
  • Click Chemistry and Applications
  • X-ray Diffraction in Crystallography
  • Genetic Mapping and Diversity in Plants and Animals
  • Reproductive Biology and Fertility
  • Crystallization and Solubility Studies
  • CRISPR and Genetic Engineering

Guangdong Pharmaceutical University
2022-2024

Hebei Agricultural University
2019-2020

Abstract Background Improving sow fertility is extremely important as it can lead to increased reproductive efficiency and thus profitability for swine producers. There are considerable differences in rates among individual animals, but the underlying molecular mechanisms remain unclear. In this study, by using different types of RNA libraries, we investigated complete transcriptome ovarian tissue during luteal (L) follicular (F) phases estrous cycle Large White pigs with high (H) low...

10.1186/s12864-020-07055-2 article EN cc-by BMC Genomics 2020-09-14

In this paper, three new iridium(III) complexes: [Ir(piq)

10.1021/acs.jmedchem.4c01026 article EN Journal of Medicinal Chemistry 2024-09-12

In this study, the ovarian tissues of Large White pigs were mined for novel circular RNAs (circRNAs), following which, their molecular characteristics and potential mechanisms fertility regulation examined. RNA sequencing was used transcriptome analysis follicles corpora lutea in sows with high (H) low (L) during follicular (F) luteal phases estrous cycle. total, 21,386 circRNA derived from 4535 host genes identified. Differentially expressed circRNAs detected LH vs. LL (1079) FH FL (1077)...

10.3390/ani10040696 article EN cc-by Animals 2020-04-17

Abstract Background: Improving sow fertility is extremely important as it can lead to increased reproductive efficiency and thus profitability for swine producers. There are considerable differences in rates among individual animals, but the underlying molecular mechanisms remain unclear. In this study, by using different types of RNA libraries, we investigated complete transcriptome ovarian tissue during luteal (L) follicular (F) phases estrous cycle Large White pigs withhigh (H) low...

10.21203/rs.2.15328/v2 preprint EN cc-by Research Square (Research Square) 2020-08-03

Abstract Background: Improving sow fertility is extremely important as it can lead to increased reproductive efficiency and thus profitability for swine producers. There are considerable differences in rates among individual animals, but the underlying molecular mechanisms remain unclear. In this study, by using different types of RNA libraries, we investigated complete transcriptome ovarian tissue during luteal (L) follicular phases (F) estrous cycle Large White pigs with high (H) low...

10.21203/rs.2.15328/v1 preprint EN cc-by Research Square (Research Square) 2019-09-30

In this article, four new Ru(II) complexes [Ru(dmbpy)2(TFBIP)](PF6)2 (dmbpy = 4,4'-dimethyl-2,2'-bipyridine, TFPIP 2-(4′-trifluoromethyl)-[1,1′-biphenyl]-4-yl)-1H-imidazo[4,5-f][1,10]phenanthroline) (Ru1), [Ru(bpy)2(TFBIP)](PF6)2 (bpy 2,2'-bipyridine) (Ru2), [Ru(phen)2(TFBIP)](PF6)2 (phen 1,10-phenanthroline) (Ru3) and [Ru(dmp)2(TFBIP)](PF6)2 (dmp 2,9-dimethyl-1,10-phenanthroline) (Ru4) were synthesized characterized by elemental analysis, HRMS, 1H NMR 13C NMR. The in vitro anticancer effect...

10.2139/ssrn.4355495 article EN 2023-01-01

In recent years, the studies of ruthenium(II) complexes on anticancer activity have been paid great attention, many Ru(II) possess high efficiency. this paper, three ligands CPIP (2-(4-chlorophenyl)-1H-imidazo[4,5-f][1,10]phenanthroline), DCPIP (2-(3,4-dichlorophenyl)-1H-imidazo[4,5-f][1,10]phenanthroline), TCPIP (2-(2,3,5-trichlorophenyl)-1H-imidazo[4,5-f][1,10]phenanthroline) and their ruthenium (II) [Ru(dip)2(CPIP)](PF6) (1, dip = 4,7-diphenyl-1,10-phenanthroline), [Ru(dip)2(DCPIP)](PF6)...

10.2139/ssrn.4440831 preprint EN 2023-01-01

Abstract Background: Improving sow fertility is extremely important as it can lead to increased reproductive efficiency and thus profitability for swine producers. There are considerable differences in rates among individual animals, but the underlying molecular mechanisms remain unclear. In this study, by using different types of RNA libraries, we investigated complete transcriptome ovarian tissue during luteal (L) follicular (F) phases estrous cycle Large White pigs with high (H) low...

10.21203/rs.2.15328/v4 preprint EN cc-by Research Square (Research Square) 2020-09-04

Abstract Background: Improving sow fertility is extremely important as it can lead to increased reproductive efficiency and thus profitability for swine producers. There are considerable differences in rates among individual animals, but the underlying molecular mechanisms remain unclear. In this study, by using different types of RNA libraries, we investigated complete transcriptome ovarian tissue during luteal (L) follicular (F) phases estrous cycle Large White pigs with high (H) low...

10.21203/rs.2.15328/v3 preprint EN cc-by Research Square (Research Square) 2020-09-03
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