Bo Zhou

ORCID: 0000-0002-7951-6813
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About
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Research Areas
  • Cancer-related molecular mechanisms research
  • Genetic and phenotypic traits in livestock
  • Estrogen and related hormone effects
  • Circular RNAs in diseases
  • Peptidase Inhibition and Analysis
  • Microtubule and mitosis dynamics
  • MicroRNA in disease regulation
  • Micro and Nano Robotics
  • Endoplasmic Reticulum Stress and Disease
  • Cytokine Signaling Pathways and Interactions
  • Nanoplatforms for cancer theranostics
  • Genetics and Neurodevelopmental Disorders
  • Cancer Cells and Metastasis
  • Genital Health and Disease
  • Orbital Angular Momentum in Optics
  • Genetic Mapping and Diversity in Plants and Animals
  • Urological Disorders and Treatments
  • Reproductive Biology and Fertility
  • Protease and Inhibitor Mechanisms
  • Synthesis and biological activity
  • Bioactive Compounds and Antitumor Agents
  • Advanced Proteomics Techniques and Applications
  • Microbial Metabolism and Applications
  • Neurological Disease Mechanisms and Treatments
  • Water Quality Monitoring and Analysis

First Affiliated Hospital of GuangXi Medical University
2025

Guangxi Medical University
2025

Hebei Agricultural University
2020

First Affiliated Hospital of Henan University of Science and Technology
2017

Huazhong University of Science and Technology
2015

Cedars-Sinai Medical Center
2014

Army Medical University
2012

Daping Hospital
2012

Shenyang Medical College
2008

Lanzhou University
2007

Protein S-acylation (also called palmitoylation) is a pervasive post-translational modification that plays critical roles in regulating protein trafficking, localization, stability, activity, and complex formation. The past decade has witnessed tremendous advances the study of S-acylation, largely owing to development novel S-acylproteomics technologies. In this review, we summarize current approaches, critically review published studies, envision future directions for burgeoning field....

10.4172/jpb.1000327 article EN Journal of Proteomics & Bioinformatics 2014-01-01

The present study aimed to assess the expression of endoplasmic reticulum oxidoreductin-1-like (ERO1L) in gastric cancer and determine its association with patient prognosis. A total 105 patients undergoing radical gastrectomy were selected for current study. Gastric tissues (the observation group) normal tissue adjacent carcinoma control resected from patients. Levels ERO1L mRNA protein tumor detected using reverse transcription-quantitative polymerase chain reaction, western blotting...

10.3892/etm.2017.4782 article EN Experimental and Therapeutic Medicine 2017-07-11

Abstract: The goal of this study was to explore minimally invasive transurethral imaging and surgery for the treatment severe, persistent hematospermia in cases that were refractory conservative treatments. included 43 patients (aged 22–77 years; average, 44.6 years) with long‐lasting, severe hematospermia, accompanied by discomfort or pain lumbosacral perineal region, dysuria, frequent micturition, decreased semen volume, and/or azoospermia. Patient symptoms had persisted 1 10 years...

10.2164/jandrol.111.015487 article EN Andrology 2012-09-10

Abstract Background Improving sow fertility is extremely important as it can lead to increased reproductive efficiency and thus profitability for swine producers. There are considerable differences in rates among individual animals, but the underlying molecular mechanisms remain unclear. In this study, by using different types of RNA libraries, we investigated complete transcriptome ovarian tissue during luteal (L) follicular (F) phases estrous cycle Large White pigs with high (H) low...

10.1186/s12864-020-07055-2 article EN cc-by BMC Genomics 2020-09-14

In this study, the ovarian tissues of Large White pigs were mined for novel circular RNAs (circRNAs), following which, their molecular characteristics and potential mechanisms fertility regulation examined. RNA sequencing was used transcriptome analysis follicles corpora lutea in sows with high (H) low (L) during follicular (F) luteal phases estrous cycle. total, 21,386 circRNA derived from 4535 host genes identified. Differentially expressed circRNAs detected LH vs. LL (1079) FH FL (1077)...

10.3390/ani10040696 article EN cc-by Animals 2020-04-17

Tamoxifen analogs (1-3) and 1,1,2-triphenylethylenes (4-7) have been synthesized by the McMurry coupling reaction. Their antiproliferative effects on MCF-7 human breast-cancer cells, HO-8910 ovarian-carcinoma (HL)-60 promyelocytic-leukemia cells were studied use of colorimetric MTT assay or sulphorhodamine B assay. Compounds 2 3 exhibited significantly higher activity all three cell lines, compound 6 a remarkably peripheral blood HL-60 than did tamoxifen. Structure-activity relationship...

10.1097/cad.0b013e3281fc9820 article EN Anti-Cancer Drugs 2007-08-17
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