A5039550891- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Phytochemical compounds biological activities
- Biological Activity of Diterpenoids and Biflavonoids
- Essential Oils and Antimicrobial Activity
- Pharmacological Effects of Natural Compounds
- Phytochemicals and Antioxidant Activities
- Sesquiterpenes and Asteraceae Studies
- Traditional Chinese Medicine Analysis
- Phytochemical and Pharmacological Studies
- Ginseng Biological Effects and Applications
- Animal Diversity and Health Studies
- Plant-based Medicinal Research
- Fungal Biology and Applications
- Traditional and Medicinal Uses of Annonaceae
- Plant chemical constituents analysis
- Medicinal plant effects and applications
- Plant Toxicity and Pharmacological Properties
- Microbial Metabolism and Applications
- Bioactive Compounds and Antitumor Agents
- Plant Molecular Biology Research
- Insect Pest Control Strategies
- Microbial Natural Products and Biosynthesis
- Phytochemistry and biological activity of medicinal plants
- Allelopathy and phytotoxic interactions
National University of Mongolia
2016-2025
Tohoku Medical and Pharmaceutical University
2015
Mongolian grasslands, including the Gobi Desert, have been exposed to drought conditions with few rains. In such harsh environments, plants highly resistant abilities against stress survive over long periods. We hypothesized that these could harbor novel and valuable genes for enhancing resistance. this study, we identified Chloris virgata, a grassland plant strong RNA-seq-based transcriptome analysis was performed uncover associated resistance in C. virgata. De novo assembly revealed 25,469...
A chemical examination of a root extract Oxytropis trichophysa led to the isolation and identification 23 compounds, including oxazole-type alkaloids isoflavonoid derivatives. Notably, three (1, 2, 3) two derivatives (7 10) were obtained from natural source for first time. In addition, O. derived 2,5-diphenyloxazoles their synthesized. Despite potential activity, antiplasmodial activities naturally occurring certain isoflavonoids remain unexplored. Therefore, both synthesized compounds...
Chemical investigation of the aerial parts Atraphaxis frutescens resulted in isolation five 7-methoxyflavonols with pyrogallol B-ring moieties (1–5), a fisetinidol glucoside (13), and benzyl glycoside (18), together 26 known compounds including flavonoids, phenylpropanoid amides, anthraquinone glycosides, lignans, derivative. The principal chemical structural feature isolated was either or catechol moiety, they showed potent 1,1-diphenyl-2-picrylhydrazyl radical scavenging activities. To...
Eleven 2,5-diphenyloxazole derivatives (1–11), together with six known isoflavonoid derivatives, were isolated from the roots of Oxytropis lanata. The (1) obtained proved to be identical a standard sample used as scintillator and liquid laser dye. other oxazole found have one four hydroxy and/or O-methyl groups in their phenyl rings. Seven are new (3–9). inhibitory activity compounds was evaluated against Trypanosoma congolense, causative agent African trypanosomosis animals. Oxazoles di-...
Eight new flavonoid-based 3′-O-β-d-glucopyranosides (1–8) and three galloyl glucosides (9, 11, 12), were isolated from the aerial parts of Saxifraga spinulosa, along with 25 known compounds. The structures compounds elucidated by spectroscopic methods. Most exhibited potent DPPH radical-scavenging activities. Further, their inhibitory activities evaluated against Babesia bovis, bigemina, caballi, Theileria equi, protozoan parasites that cause piroplasmosis in livestock. results indicated...
Novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza A virus (IAV), and norovirus (NV) are highly contagious pathogens that threaten human health. Here we focused on the antiviral potential of medicinal herb, Saxifraga spinulosa (SS). Water-soluble extracts SS were prepared, their virus-inactivating activity was evaluated against SARS-CoV-2 IAV; also examined virucidal feline calicivirus murine norovirus, which surrogates for NV. Among our findings, found SS-derived...
Ephedrae herba has been used in traditional Chinese and Japanese (Kampo) medicine from ancient times, with the primary resource being China. In present study, a field survey as well molecular chemical assessments were conducted on Ephedra plants Mongolia to clarify whether they could be an alternative of Kampo medicine. sinica, E. equisetina, przewalskii, regeliana, monosperma unknown taxon (ESP) collected divided into 9 genotypes basis nucleotide sequences 18S ribosomal RNA (rRNA) gene trnK...
From an extract of the aerial parts Dracocephalum ruyschiana, five new flavone tetraglycosides, benzyl alcohol glycosides, and 19 known compounds were isolated. The tetraglycosides contain a 7-O-β-d-glucopyranosyl-(1→2)-β-d-glucopyranosyl-(1→2)-[α-l-rhamnopyranosyl-(1→6)]-β-d-glucopyranosyl moiety. glycosides had acyl groups on their glycosyl or aglycone moieties. tested for antioxidant activity using DPPH. Although not active, phenylpropanoylquinic acid derivatives revealed as radical...
The aim of this study was the evaluation antioxidant capacity Cotoneaster melanocarpus Lodd. and identification active constituents plant. C. is a shrub indigenous to Mongolia used in Traditional Mongolian Medicine as styptic. Before extraction, plant material separated into three parts: young sterile shoots, older stems leaves. All these parts were extracted with water, methanol, ethyl acetate, dichloromethane hexane, successively. methanolic extract shoots showed highest activity DPPH...
Eight isovaleryllignans (1–4 and 8–11), three isovalerylphenylpropanoids (5–7), known lignans (12–14), four compounds were isolated from an extract of the aerial part Brachanthemum gobicum. The structures elucidated based on NMR MS data analyses. enantiomers 1–3, 5, 8, 9 using chiral-phase HPLC, absolute configurations 1a/1b–3a/3b, 5a/5b, 8a/8b, 9a/9b their optical rotations ECD spectra; other assumed to be racemic or scalemic by HPLC analyses rotation data. Some acylated (racemic mixtures)...