Abstract Bacterial resistance and excessive inflammation are common issues that hinder wound healing. Antimicrobial peptides (AMPs) offer a promising versatile antibacterial option compared to traditional antibiotics, with additional anti-inflammatory properties. However, the applications of AMPs limited by their antimicrobial effects stability against bacterial degradation. TFNAs regarded as drug delivery platform could enhance properties nanodrugs. Therefore, in this study, composite...

ABSTRACT Conductive polymer hydrogels (CPHs), which combine the unique advantages of and organic conductors, have received wide attention due to their adjustable mechanical properties, biocompatibility, self‐healing, hydrophilicity, ease preparation. With doping engineering incorporation with other functional nanomaterials, CPHs exhibited excellent physical/chemical properties. been widely used in various electronic devices, especially field sensors its sensitivity external stimuli. This...

The CRISPR-Cas system has been extensively employed as a genome editing tool with the dCas9-based transcriptional activation emerging particularly promising approach for gene in treatment of diseases at level. Nevertheless, challenge achieving effective spatiotemporal control dCas9 thus far restricted its broader application. In this study, we present an miRNA-responsive CRISPR-dCas9 (mCTA) system. This is capable responding specifically to exogenous and endogenous miRNAs mammalian cells...

ABSTRACT To explore environmentally benign solvents for the absorption of NO and NO2, a series caprolactam tetrabutyl ammonium halide ionic liquids were synthesized. The solubility NO2 was measured at temperatures ranging from 298.2 to 363.2 K atmospheric pressure, following trend in with various anions observed, respectively: F > Br Cl F. Moreover, as temperature increased 308.15 363.15 mole ratio 2:1 6:1, increased. Alternatively, decreased 298.15 K, 6:1. desorption practically reversible...

To explore environmentally benign solvents for absorbing and using H2S, a series of caprolactam tetrabutyl ammonium bromide ionic liquids were synthesized, the solubilities H2S in which measured at 303.2−363.2 K atmospheric pressure. The solubility liquid (1:1 mole ratio) was 5.40% 303.2 ambient pressure, decreased sharply as temperature increased, increased with increasing ratio caprolactam. absorption desorption practically reversible liquids, characterized by nuclear magnetic resonance....

Histone deacetylase 6 (HDAC6) enzyme plays a crucial role in variety of cellular processes related to cancer, and inhibition HDAC6 is emerging as an effective strategy for cancer treatment. Although several hydroxamate-based inhibitors showed promising anticancer activities, the intrinsic defects such poor selectivity, stability, pharmacokinetics limited their application. In this study, potent selenocyanide-bearing inhibitor, 5-phenylcarbamoylpentyl selenocyanide (SelSA), was evaluated its...

Implications: During the production of penicillin, a mass waste bacterial residue is generated. In past, residues have been used for food additives. Unfortunately, doubts their suitability as feedstock raised because small amount antibiotics and degradation products remaining in residues. So, penicillin one hazardous wastes. Therefore, should be managed accordance with waste. To get right method, was characterized.

Epoxy and its composites are widely used as raw materials for the solid insulations in gas insulated switchgear (GIS) worldwide due to their excellent dielectric properties, thermal stability, corrosion resistance, ease of processing. These insulation show aging phenomena under multiple stresses electrical, vibration during GIS operation, which reduces electrical mechanical strength insulation, further leads operational failures GIS. Therefore, it is crucial study characteristics epoxy...

The electrical conductivities of binary systems caprolactam tetrabutylammonium bromide ionic liquid + solvent (solvent = water, ethanol, 2-propanol, 1-butanol) were measured at mole fractions from (3.60·10−4 to 6.82·10−2) and temperatures (290.55 342.25) K. the mixtures increase with increasing temperature, concentration liquid, decreasing caprolactam/tetrabutylammonium ratio in liquid. conductivity values (ionic solvent) decrease following order: water > ethanol 2-propanol 1-butanol.

Some samples of semi-dry flue gas desulfurization (FGD) ash were taken from sinter a steel factory. Scanning electron microscope (SEM) and X-ray diffraction (XRD) analyses employed to identify the in order investigate their physical chemical characteristics. The results show that FGD factory is stable under atmospheric conditions. It has irregular shape, smooth surface loose construction. size particles around 0.5—25 µm, average about 5 µm median diameter 4.18 µm. Semi-dry consists CaSO 3 ,...

The oxytetracycline bacterial residue–activated carbon (OBR-AC) prepared from residue with K2CO3 under chemical activation was studied. effects of temperature, time, and ratio on the specific surface area (SSA) methylene blue adsorption (MBA) were Characterization optimum OBR-AC performed by using scanning electron microscopy (SEM), pore structure (PS,) Fourier-transform infrared spectroscopy (FT-IR). parameters as follows: 800°C 3 hr 1:3 ratio. SSA MBA conditions 1593.09 m2/g 117.0 mg/g,...

Regeneration of soft tissues, especially those requiring complex vascularization, is a major challenge in the field tissue engineering. The current types engineering scaffolds include sponges, electric spinning silk, hydrogels, and 3D printed biomaterials. Among them, hydrogels have unique property mimicking extracellular matrix (ECM), which can provide relatively stable microenvironment for cellular activities facilitate cell adhesion, proliferation, differentiation; thus, become promising...

Abstract Fertilizer plays an important role in agricultural development. However, the soil environment of tea gardens has been deteriorated and growth trees hindered by long-term excessive chemical fertilizer used gardens. To study effects reducing on quality components Tieguanyin leaves, garden located yellow-red was treated with three consecutive times five recipes fertilizer. The results showed that appropriate reduction applied can increase contents potassium organic matter soil,...