A5011373529- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Spinal Fractures and Fixation Techniques
- Infectious Diseases and Tuberculosis
- Spine and Intervertebral Disc Pathology
- Orthopedic Infections and Treatments
- Bone Tissue Engineering Materials
- Advanced Cellulose Research Studies
- Electrospun Nanofibers in Biomedical Applications
- Bone Metabolism and Diseases
- Osteoarthritis Treatment and Mechanisms
- Nutrition, Health and Food Behavior
- Scoliosis diagnosis and treatment
- Pelvic and Acetabular Injuries
- Total Knee Arthroplasty Outcomes
- Orthopedic Surgery and Rehabilitation
- Bone fractures and treatments
- MicroRNA in disease regulation
- Orthopaedic implants and arthroplasty
- Diet and metabolism studies
- Graphene and Nanomaterials Applications
- Elbow and Forearm Trauma Treatment
- Bone health and osteoporosis research
- Hip and Femur Fractures
- biodegradable polymer synthesis and properties
Xiangya Hospital Central South University
2016-2025
Central South University
2016-2025
Optum (United States)
2024-2025
Fujian Medical University
2013-2025
Union Hospital
2013-2025
General Mills (United States)
2019-2024
Winthrop Rockefeller Foundation
2024
University of Arkansas for Medical Sciences
2024
Chongqing Medical University
2011-2023
Chuxiong Normal University
2021-2023
To estimate prevalence of childhood-onset Duchenne and Becker muscular dystrophies (DBMD) in 6 sites the United States by race/ethnicity phenotype (Duchenne dystrophy [DMD] or [BMD]).
Due to increasing morbidity worldwide, fractures are becoming an emerging public health concern. This study aimed investigate the effect of metformin on healing osteoporotic as well normal fractures. Type H vessels have recently been identified a bone-specific vascular subtype that supports osteogenesis. Here, we show accelerated fracture in both and mice. Moreover, promoted angiogenesis vitro under hypoxia type vessel formation throughout healing. Mechanistically, increased expression...
Background: Spine surgeons discourage the use of nonsteroidal anti-inflammatory drugs following spine arthrodesis because their inhibitory effect on bone-healing. To our knowledge, there are no data effects new cyclooxygenase-2 inhibitors We undertook this study to determine these more selective spinal fusion in a rabbit model. Methods: Seventy-two New Zealand White rabbits underwent posterolateral intertransverse process with autologous iliac crest bone. Sixty-six survived surgical...
Osteogenesis of mesenchymal stem cells (MSCs) has played a necessary role in the repair bone. According to some reports, microRNAs participate different physiological activity cells, including cell differentiation. This study investigated function that miR-139-5p plays osteogenic differentiation human bone marrow MSCs (hBMSCs). In addition miR-139-5p, effects alkaline phosphatase (ALP), membrane-bound metalloenzyme is considered an early marker, have also been investigated. Calcium-rich...
Sizing treatment of glass fiber has been shown to effectively improve fiber-matrix interfacial adhesion whereas few studies have conducted on the sizing natural fibers. In this work, corn was subjected alkali and treatments. The treated fibers were used prepare reinforced polylactide (CF/PLA) composites through mechanical mixing injection molding. Fiber surface, tensile fracture properties thermo-mechanical behavior various CF/PLA characterized. SEM observation indicates better between...
miR-199b-5p is up-regulated significantly during the osteogenesis process in human bone marrow stromal cells (BMSCs). Inhibiting notably reduces while over-expressing promotes BMSCs osteoblast differentiation, suggested by alternations of osteogenic genes expression, ALP activity and ARS-stained mineral nodules. exerts its role BMSC most probably through GSK-3β/β-catenin signaling pathway. In conclusion, present study revealed for first time that plays a positive differentiation.
In this study, we aimed to investigate the causal associations of brain structure with bone mineral density (BMD). Based on genome-wide association study (GWAS) summary statistics 1 325 imaging-derived phenotypes (BIDPs) from UK Biobank and GWAS datasets 5 BMD locations, including total body, femoral neck, lumbar spine, forearm, heel GEFOS Consortium, linkage disequilibrium score regression (LDSC) was conducted determine genetic correlations, Mendelian randomization (MR) then performed...
Abstract In order to repair critical‐sized bone defects, various polylactic acid‐glycolic acid (PLGA)‐based hybrid scaffolds are successfully developed as substitutes. However, the byproducts of these PLGA‐based known acidify implanted site, inducing tiresome acidic inflammation. Moreover, degradation productions cannot offer an osteo‐friendly microenvironment at matching natural healing. Herein, inspired by atlas bone‐healing process, osteo‐microenvironment stage‐regulative scaffold...
A novel sphere-like carbonized bacterial cellulose/graphene nanocomposite with a honeycomb-like surface morphology and three-dimensional (3D) porous structure was synthesized<italic>via</italic>a facile scalable one-pot<italic>in situ</italic>biosynthesis route carbonization.
To investigate associations between eating frequency and energy intake, density, diet quality body weight status in adults from the USA, combined data 2009-2010 2011-2012 National Health Nutrition Examination Survey (NHANES) were used this study. The first 24-h dietary recall eligible participants (4017 men 3774 women) to calculate frequency, as well density Healthy Eating Index 2010 (HEI-2010), a measure of quality. BMI waist circumference obtained NHANES measures data. Adjusting for...
Abstract The osteogenic differentiation of human bone mesenchymal stromal cells (BMSCs) has been considered as a central issue in fracture healing. Wnt signaling could promote BMSC through inhibiting PPARγ. During atrophic nonunion, signaling-related factors, WNT5A and FZD3 proteins, were significantly reduced, along with downregulation Runx2, ALP, Collagen I upregulation Here, we performed microarray analysis to identify differentially expressed miRNAs nonunion tissues that associated...
Background: A prospective, randomized, double-blind, placebo-controlled study was performed. The routine usage of TA in spinal surgery is controversial. Only a few studies have focused on patients undergoing posterior lumbar for stenosis or spondylolisthesis, although large clinical cohort exists the population. This aimed to evaluate effect and safety reducing perioperative blood loss spondylolisthesis. Methods: 100 eligible out 126 were randomized receive either bolus dose 30 mg/kg i.v,...