A5074206364- Healthcare Technology and Patient Monitoring
- Neonatal and Maternal Infections
- Neonatal and fetal brain pathology
- Neonatal Respiratory Health Research
- Patient Safety and Medication Errors
- Atomic and Subatomic Physics Research
- Cardiac Arrest and Resuscitation
- Anesthesia and Neurotoxicity Research
- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Use and Resistance
- Skin and Cellular Biology Research
- Emergency and Acute Care Studies
- Bacterial Identification and Susceptibility Testing
- Neonatal Health and Biochemistry
- Streptococcal Infections and Treatments
- Infant Development and Preterm Care
- Healthcare Decision-Making and Restraints
- Non-Invasive Vital Sign Monitoring
- Craniofacial Disorders and Treatments
- Congenital Heart Disease Studies
- Congenital Diaphragmatic Hernia Studies
- Quality and Safety in Healthcare
- Pneumonia and Respiratory Infections
- Parasitic Infections and Diagnostics
- Abdominal vascular conditions and treatments
Research Institute Hospital 12 de Octubre
2014-2024
Hospital Universitario 12 De Octubre
2014-2023
Instituto de Salud Carlos III
2022
The use of cerebral oximetry monitoring in the care extremely preterm infants is increasing. However, evidence that its improves clinical outcomes lacking. Download a PDF Research Summary. In this randomized, phase 3 trial conducted at 70 sites 17 countries, we assigned (gestational age, <28 weeks), within 6 hours after birth, to receive treatment guided by for first 72 birth or usual care. primary outcome was composite death severe brain injury on ultrasonography 36 weeks' postmenstrual...
ABSTRACT An epidemiological, multicenter, noninterventional, observational case-control study was conducted to describe the performance of serum beta- d -glucan (BDG) and Candida PCR in blood, serum, sterile samples for diagnosis invasive candidiasis (IC) very-low-birth-weight (VLBW) preterm neonates compare these techniques with culture from blood other sites. Seventeen centers participated study, number episodes analyzed 159. A total 9 IC patients (7 confirmed 2 probable) 150 suspected...
Random safety audits (RSA) are a tool enabling prevention of adverse events, but they have not been widely used in hospitals. The aim this study was to use RSAs assess and compare the frequency appropriate infusion pump systems Neonatal Intensive Care Unit (NICU) before after quality improvement interventions analyse intravenous medication programming data. Prospective, observational comparing Alaris® CC smart pumps through over two periods, from 1 January 31 December 2012 November 2014...
Blood cultures are the gold standard for detecting bacteremia. We have studied time to positivity of blood in our neonatal unit reduce antibiotic doses patients with a negative culture. Empirical treatment sepsis could be withdrawn 24 hours after obtaining cultures.
Antibiotic burden is a critical issue in neonatal intensive care units (NICU) and antibiotic use considered quality indicator of care. Our aim was to optimize through improvement (QI) initiative that included revision departmental protocols implementation surveillance system based on process indicators.This descriptive study cohort all very low birth weight (VLBW) infants admitted the NICU from 2014 2019. A series QI interventions were made during period indicators. The primary outcome...
Abstract Background Antibiotic use for early-onset sepsis represents a high percentage of antibiotic consumption in the neonatal setting. Measures to assess infants at risk are needed optimize use. Our primary objective was impact departmental guideline on among term with suspected EOS not confirmed, our unit. Methods Retrospective cohort study, compare during baseline period January December 2018, and postintervention from October 2019, September 2020, respectively. The outcome measured by...
Background . Random safety audits (RSAs) are a tool but have not been widely used in hospitals. Objectives To determine the frequency of proper use equipment mechanisms relation to monitoring and mechanical ventilation by performing RSAs. The study also determined whether factors related patient, time period, or characteristics area admission influenced how device systems were used. Methods A prospective observational was conducted level III-C Neonatal Intensive Care Unit (NICU) during 2012....
Random audits are a safety tool to help in the prevention of adverse events, but they have not been widely used hospitals. The aim study was determine, through random audits, whether information and material required for resuscitation were available each patient neonatal intensive care unit determine if factors related patient, time or location affect implementation recommendations.Prospective observational conducted level III-C during year 2012. evaluation written on endotracheal tube, mask...
72Several studies have been conducted to investigate the feasibility of customized nasal masks produced by three-dimensional (3D) facial imaging and printing for continuous positive airway pressure in adults premature mannequin. In addition replicating entire process, we applied mask a patient who weighed less than 1,000 g. Facial scanning was performed. The study were manufactured using stereolithography with 3D printer model Form3BL (FormLABS). Elastic 50 resin used as material. We...
Abstract Background SafeBoosC-III is a pragmatic, multinational clinical trial evaluating cerebral oximetry-guided treatment for extremely preterm infants. In total, 1601 infants were randomised across 70 sites in Asia, Europe, and USA. To enhance data quality patient care, web-based training program was implemented staff. We now report on the processes. Methods All modules consisted of initial learning material followed by case-based quiz, with elaborate responses to correct as well wrong...
Currently, there is no validated method for estimating antimicrobial consumption in the neonatal population, as it exists adults using Defined Daily Doses (DDD). In neonatology, although are different methods, each one with advantages and disadvantages, unified criterion use. The aim of this study to validate DDD designed a new standardised form over population.The validation DDD, Phase II research project, was carried out through descriptive observational study. Periodic cut-offs were...
Background: Fetoscopic laser photocoagulation can directly injure fetal skin and may at birth resemble aplasia cutis congenita (ACC). Case report: A twin monochorionic pregnancy was complicated by twin-to-twin transfusion syndrome requiring in utero photocoagulation, resulting the death of one twin. After birth, viable baby presented lesions both legs that were congruent with laser-induced burns. Conclusions: Laser-induced burns present as asymmetric superficial non-necrotic or ulcerated...
A 39-year-old woman at 25 weeks of pregnancy with marfanoid habitus and a medical history thoracic aortic aneurysm, was admitted to the emergency department our hospital due pain. angio-CT performed rule out an dissection, using iodinated contrast media ioversol. This examination confirmed presence ascending intramural haematoma. An caesarean 26+6 w GA following …
<h3>Background</h3> Real time safety auditing (RTSA) has not been widely used in hospitals. There is insufficient information on its use as a tool for patient safety. <h3>Aim</h3> To determine the frequency of appropriate security systems technological equipment monitoring and respiratory support through RTSA. estimate whether characteristics patient, or location influence use. <h3>Methods</h3> Prospective observational study conducted during 2012 tertiary NICU. 115 days were randomly...
Objective This study aimed to assess the applicability of insertion small diameter catheters through femoral vein in extremely low-birth-weight (ELBW) infants. Study Design All (Silastic or arterial catheter [FAC]) inserted ELBW infants a tertiary level neonatal intensive care unit were retrospectively reviewed. Success rate, dwelling time, and percutaneously central venous catheter–related complications recorded. Results Thirteen seven Mean gestational age at birth was 25+3 weeks (standard...
Abstract Background Extremely preterm infants have a high mortality and morbidity. Here, we present statistical analysis plan for secondary Bayesian analyses of the pragmatic, sufficiently powered multinational, trial—SafeBoosC III—evaluating benefits harms cerebral oximetry monitoring plus treatment guideline versus usual care such infants. Methods The SafeBoosC-III trial is an investigator-initiated, open-label, randomised, phase III clinical with parallel-group design. randomised 1601...