A5074174226- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Gastroesophageal reflux and treatments
- Surgical Simulation and Training
- Lung Cancer Diagnosis and Treatment
- Gastrointestinal Tumor Research and Treatment
- Anatomy and Medical Technology
- Cardiac, Anesthesia and Surgical Outcomes
- Metastasis and carcinoma case studies
- Eosinophilic Esophagitis
- Colorectal Cancer Surgical Treatments
- Minimally Invasive Surgical Techniques
- Helicobacter pylori-related gastroenterology studies
- Physics and Engineering Research Articles
- Diverticular Disease and Complications
- Neonatal Respiratory Health Research
- Bariatric Surgery and Outcomes
- Neonatal and fetal brain pathology
- Gallbladder and Bile Duct Disorders
- Dysphagia Assessment and Management
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Treatments and Mutations
- Medical Practices and Rehabilitation
- Abdominal Surgery and Complications
University Hospital Cologne
2017-2025
University of Cologne
2016-2025
University Medical Center Freiburg
2022-2025
University of Freiburg
2022-2025
Klinik und Poliklinik für Psychosomatik und Psychotherapie
2017-2025
Institut de Recherche contre les Cancers de l’Appareil Digestif
2025
LVR-Klinik Köln
2011-2024
Copenhagen University Hospital
2021-2024
Rigshospitalet
2021-2024
Centrum für Integrierte Onkologie
2024
The use of cerebral oximetry monitoring in the care extremely preterm infants is increasing. However, evidence that its improves clinical outcomes lacking. Download a PDF Research Summary. In this randomized, phase 3 trial conducted at 70 sites 17 countries, we assigned (gestational age, <28 weeks), within 6 hours after birth, to receive treatment guided by for first 72 birth or usual care. primary outcome was composite death severe brain injury on ultrasonography 36 weeks' postmenstrual...
Esophageal perforations and postoperative leakage of esophagogastrostomy are considered to be life-threatening conditions due the development mediastinitis consecutive sepsis. Vacuum-assisted closure (VAC), a well-established treatment method for superficial infected wounds, is based on negative pressure applied wound via vacuum-sealed sponge. Endoluminal VAC (E-VAC) therapy novel method, experience with its esophageal application limited.This retrospective study summarizes center high...
Background: Epidemiological studies have shown an equal gender distribution of obesity in the United States; however, literature suggests approximately 80% patients undergoing bariatric surgery are female. The aim this study is to identify factors that contribute disparity. Study Design: A retrospective analysis Nationwide Inpatient Sample was performed. Obese who underwent open or laparoscopic gastric bypass sleeve gastrectomy were identified using International Classification Diseases, 9th...
Objective: This international multicenter study by the Upper GI International Robotic Association aimed to gain insight in current techniques and outcomes of RAMIE worldwide. Background: Current evidence for originates from single-center studies, which may not be generalizable experience. Methods: Twenty centers Europe, Asia, North-America, South-America participated 2016 2019. Main endpoints included surgical techniques, clinical outcomes, early oncological results ramie. Results: A total...
Abstract Background Adenocarcinoma of the gastroesophageal junction (GEJ) Siewert type II can be resected by transthoracic esophagectomy or transhiatal extended gastrectomy. Both allow for a complete tumor resection, yet there is an ongoing controversy about which surgical approach superior with regards to quality life, oncological outcomes and survival. While some studies suggest better outcome after esophagectomy, others favor gastrectomy postoperative life. To date, only retrospective are...
Zusammenfassung Die Chirurgie steht vor bedeutenden Herausforderungen, die sowohl aus Veränderungen in der medizinischen Ausbildung als auch sinkenden Attraktivität des chirurgischen Berufswegs für angehende Ärzt:innen westlichen Welt resultieren. So haben sich Erwartungen Studierenden an ihren zukünftigen Arbeitsplatz geändert, wobei Themen wie Unsicherheiten beruflichen Planung, eine unausgewogene Work-Life-Balance sowie fehlende Vereinbarkeit von Familie und Beruf zunehmend relevant sind....
Abstract Valid biomarkers for a better prognostic prediction of the clinical course in esophageal adenocarcinoma (EAC) are still not implemented. Integrin alpha V (ITGAV), transmembrane glycoprotein responsible cell-to-matrix binding has been found to enhance tumor progression several entities. The expression pattern and biological role ITGAV analyzed so far. Aim study is evaluate level very large collective EAC its impact on individual patients´ prognosis. 585 patients with were...
Abstract Introduction Transthoracic esophagectomy is a highly complex and sophisticated procedure with high morbidity rates significant mortality. Surgical access has consistently become less invasive, transitioning from open to hybrid (HE) then totally minimally invasive (MIE), most recently robot-assisted (RAMIE), each step demonstrating improved patient outcomes. Aim of this study more than 600 patients complete propensity-score matched comparison postoperative short-term outcomes after...
A large variety of foregut symptoms can occur in patients with gastroesophageal reflux disease (GERD), which overlap other disorders such as somatoform and dyspepsia. Due to unclear diagnostic situations, these are often not adequately treated. The aim this study was the evaluation symptoms, referred for possible antireflux surgery, regarding their relationship GERD somatization tendencies based on control data from an unselected population. Symptom screening were initiated both volunteers...
Self-expandable metal stents (SEMS) and endoscopic vacuum therapy (EVT) are options for treating leaks of the esophagus. VACStent® is a variant SEMS that aims to combine advantages EVT in one device. Due this unique construction, can build barrier leak facilitate wound healing with EVT, all while maintaining intestinal passage. We present first prospective feasibility study upper gastrointestinal tract. Between September 2019 November 2020, we performed prospective, investigator-initiated,...
Indocyanine green (ICG) is one of the only clinically approved near-infrared (NIR) fluorophores used during fluorescence-guided surgery (FGS), but it lacks tumor specificity for pancreatic ductal adenocarcinoma (PDAC). Several tumor-targeted fluorescent probes have been evaluated in PDAC patients, yet no uniformity or consensus exists among surgical community on current and future needs FGS surgery. In this first-published report PDAC, expert opinions were gathered use recommendations from...
Oesophagectomy is an operation with a high risk of postoperative complications. The aim this single-centre retrospective study was to apply machine-learning methods predict complications (Clavien-Dindo grade IIIa or higher) and specific adverse events.Patients resectable adenocarcinoma squamous cell carcinoma the oesophagus gastro-oesophageal junction who underwent Ivor Lewis oesophagectomy between 2016 2021 were included. tested algorithms logistic regression after recursive feature...
Background The rapid adoption of robotic surgical systems across Europe has led to a critical gap in training and credentialing for gastrointestinal (GI) surgeons. Currently, there is no existing standardised curriculum guide training, assessment certification GI trainees. This manuscript describes the protocol achieve pan-European consensus on essential components comprehensive programme surgery through five-stage process. Methods analysis In Stage 1, Steering Committee, consisting...