A5008663754- Global Cancer Incidence and Screening
- Colorectal Cancer Screening and Detection
- Cancer Risks and Factors
- COVID-19 and healthcare impacts
- Economic and Financial Impacts of Cancer
- Digital Radiography and Breast Imaging
- Health Systems, Economic Evaluations, Quality of Life
- Social and Intergroup Psychology
- Breast Cancer Treatment Studies
- Climate Change Communication and Perception
- BRCA gene mutations in cancer
- Cancer survivorship and care
- Economic and Environmental Valuation
- Behavioral Health and Interventions
- AI in cancer detection
- Healthcare cost, quality, practices
- Ethics in Clinical Research
- demographic modeling and climate adaptation
Radboud University Nijmegen
2024-2025
Radboud University Medical Center
2024-2025
Erasmus University Rotterdam
2020-2024
Erasmus MC
2020-2024
Abstract Currently, all European countries offer some form of breast cancer screening. Nevertheless, disparities exist in the status implementation, attendance and extent opportunistic As a result, screening has not yet reached its full potential. We examined how many deaths could be prevented if would biennially screen women aged 50 to 69 for cancer. calculated number already due as well which additionally total examination coverage (organised plus opportunistic) reach 100%. The...
Many breast, cervical, and colorectal cancer screening programmes were disrupted due to the COVID-19 pandemic. This study aimed estimate effects of five restart strategies after disruption on required capacity burden.Microsimulation models simulated for screening. The estimated capacity, incidence, cancer-specific mortality a 6 months. varied in whether screens caught up or not and, if so, immediately delayed, upper age limit was increased.The without catch-up missed led an increase 2.0,...
Abstract Objectives It is uncertain what the effects of introducing digital breast tomosynthesis (DBT) in Dutch cancer screening programme would be on detection, recall, and interval cancers (ICs), while reading times are expected to increase. Therefore, an investigation into efficiency cost-effectiveness DBT optimising required. Materials methods The Screening Tomosynthesis trial with advanced REAding Methods (STREAM) aims include 17,275 women (age 50–72 years) eligible for Netherlands two...
Abstract Breast cancer screening policies have been designed decades ago, but current strategies may not be optimal anymore. Next to that, capacity issues restrict feasibility. This cost‐effectiveness study evaluates an extensive set of breast in the Netherlands. Using Microsimulation Screening Analysis‐Breast (MISCAN‐Breast) model, 920 with varying starting ages (40‐60), stopping (64‐84) and intervals (1‐4 years) were simulated. The number quality adjusted life years (QALYs) gained...
BackgroundMany European countries offer organised population-based breast, cervical, and colorectal cancer screening programmes. Around age 55 60, Dutch women are invited to all three We examined the extent which participation concurs identified factors influencing concurrent participation.Materials methodsIndividual level data from invitations between 2017 2019 were extracted registry. The percentages of participating in three, two, one, or none programmes around before subsequent round...
To assess the effect of an information leaflet on knowledge, explicit attitudes, implicit associations, and attendance for breast cancer screening.
Abstract In breast cancer research, utility assumptions are outdated and inconsistent which may affect the results of quality adjusted life year (QALY) calculations thereby cost‐effectiveness analyses (CEAs). Four hundred sixty four female patients with treated at Erasmus MC, Netherlands, completed EQ‐5D‐5L questionnaires from diagnosis throughout their treatment. Average utilities were calculated stratified by age These applied in CEAs analysing 920 screening policies differing eligible...
Abstract Women tend to make a decision about participation in breast cancer screening and adhere this for future invitations. Therefore, our study aimed provide high‐quality information on cumulative risks of false‐positive (FP) recall screen‐detected over multiple examinations. Individual Dutch registry data (2005‐2018) were gathered subsequent examinations 92 902 women age 49 51 years 2005. Survival analyses used calculate FP true‐positive (TP) result after seven Data from 66 472 58 59...
Abstract Purpose Normative utility scores represent the health related quality of life general population, are utmost importance in cost-effectiveness studies and should reflect relevant sexes age groups. The aim this study was to estimate EQ-5D-5L normative a population Dutch females, stratified by age, compare these those female populations three other countries. Methods women completed online between January July 2020. Mean utilities were computed using value set, tested for differences...