A5023988535- COVID-19 epidemiological studies
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Mosquito-borne diseases and control
- Vaccine Coverage and Hesitancy
- Parasites and Host Interactions
- Genetic and phenotypic traits in livestock
- COVID-19 and Mental Health
- Wildlife Ecology and Conservation
- Reproductive System and Pregnancy
- Milk Quality and Mastitis in Dairy Cows
- Reproductive tract infections research
- Reproductive Physiology in Livestock
- Parasitic Diseases Research and Treatment
- Viral Infections and Outbreaks Research
- Parasite Biology and Host Interactions
Kyoto University
2021-2024
Lancaster University
2023-2024
BackgroundIn Japan, vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was initiated on 17 February 2021, mainly using messenger RNA vaccines and prioritizing health care professionals. Whereas nationwide alleviated the disease 2019 (COVID-19)-related burden, population impact has yet to be quantified in Japan. We aimed estimate numbers of COVID-19 cases deaths prevented that were attributable reduced risk among vaccinated individuals via a statistical modeling...
<abstract> <p>In Japan, a prioritized COVID-19 vaccination program using Pfizer/BioNTech messenger RNA (mRNA) vaccine among healthcare workers commenced on February 17, 2021. As coverage increases, clusters in and elderly care facilities including hospitals nursing homes are expected to be reduced. The present study aimed explicitly estimate the protective effect of reducing cluster incidence those facilities. A mathematical model was formulated three pieces information: (1) from...
Coronavirus disease 2019 (COVID-19) booster vaccination has been implemented globally in the midst of surges infection due to Delta and Omicron variants severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The objective present study was a framework estimate proportion population that is immune symptomatic SARS-CoV-2 with variant (immune proportion) Japan, considering waning immunity resulting from naturally acquired infection. We quantified decay rate against conferred by second...
Abstract Over the past decade, considerable progress has been made in control, elimination, and eradication of neglected tropical diseases (NTDs). Despite these advances, most NTD programs have recently experienced important setbacks; for example, interventions were some frequently severely impacted by service disruptions due to coronavirus disease 2019 (COVID-19) pandemic. Mathematical modeling can help inform selection meet targets set out road map 2021–2030, such studies should prioritize...
Trachoma is the commonest infectious cause of blindness worldwide. Efforts are being made to eliminate trachoma as a public health problem globally. However, prevalence decreases, it becomes more challenging precisely predict prevalence. We demonstrate how model-based geostatistics (MBG) can be used reliable, efficient, and widely applicable tool assess elimination status trachoma.We analysed surveillance data from Brazil, Malawi, Niger. developed geostatistical Binomial models trachomatous...
Public health and social measures (PHSM) against COVID-19 in Japan involve requesting the public to voluntarily reduce contact; these are not legally binding. The effectiveness of such PHSM has been questioned with emergence SARS-CoV-2 Alpha variant (B.1.1.7), which exhibited elevated transmissibility.We investigated epidemic dynamics during fourth wave from March June 2021 involving pre-emergency declaration a state emergency (SoE). We estimated effective reproduction number (Rt ) before...
COVID-19 vaccination in Japan started on February 17, 2021. Because the timing of and risk severe greatly varied with age, present study aimed to monitor age-specific fractions population who were immune SARS-CoV-2 infection after vaccination.Natural remained extremely rare, accounting for less than 5% by end 2021; thus, we ignored natural infection-induced immunity focused vaccine-induced immunity. We estimated fraction age group using registry data from 2021, October accounted two...
Stringent public health and social measures against COVID-19 infection were implemented to avoid an overwhelming hospital caseload excessive number of deaths, especially among elderly people. We analyzed population-level immunity predicted mortality, calculated as the potential deaths on a given calendar date in Japan, develop science-based exit strategy from stringent control measures.
<title>Abstract</title> Background: Model-based geostatistics (MBG) is increasingly used for estimating the prevalence of neglected tropical diseases, including trachoma, in low- and middle-income countries. We sought to investigate impact spatially referenced covariates improve spatial predictions trachomatous inflammation—follicular (TF) generated by MBG. To this end, we assessed ability explain variation TF reduce uncertainty assessment elimination pre-defined evaluation units (EUs)....
2020年12月から世界中でCOVID-19ワクチン接種が推進されてきた．わが国では2021年２月17日からCOVID-19のワクチン接種が実施され，同年12月1日にはブースター（３回目）接種も開始された．COVID-19の流行対策の政策の決定や評価，変異株によって大きく変化する流行状況の分析において，日本国内での人口レベルでの免疫状況（免疫ランドスケープ）を把握することは欠かせない．本稿では数理モデルを用いた免疫ランドスケープの定量化や予測の方法を紹介する．構築されたモデルでは，COVID-19ワクチン接種率の予測，それぞれの流行株変異株に対するワクチン効果，１回目接種後の免疫の上昇（immune build-up），２・3回目接種後の免疫失活，自然感染による免疫が考慮され，その実装によって年齢群別の免疫保持者割合を把握することが可能になった．