Carborane-based host materials were prepared to fabricate deep blue phosphorescence organic light-emitting diodes (PHOLEDs), which constituted three distinctive geometrical structures stemming from the corresponding different isomeric forms of carboranes, namely, ortho-, meta-, and para-carboranes. These consist two carbazolyl phenyl (CzPh) groups as photoactive units on each side carborane carbons be bis[4-(N-carbazolyl)phenyl]carboranes, o-Cb, m-Cb, p-Cb. To elaborate role comparative...

A series of constrained geometry group 4 metal complexes containing the (N,N'-dimethylaminomethyl) dicarbollyl ligand DcabNH [nido-7-NHMe2(CH2)-8-R-7,8-C2B9H10] (3) was prepared. New types titanium with formula (DcabN)TiCl2, [{(η5-RC2B9H9)(CH2)(η1-NMe2)}TiCl2] (R = H, 4a; Me, 4b), were produced by reaction potassium salt 3 tetrachloride. The Ti(NMe2)4 in toluene afforded (DcabN)Ti(NMe2)2, [{(η5-RC2B9H9)(CH2)(η1-NMe2)}Ti(NMe2)2] (5) a; b), which readily reacted Me3SiCl to yield corresponding...

A new type of organic dyad that can induce low-energy photosensitization has been developed; electron donor and acceptor units are boron dipyrromethene (BODIPY) ortho-carborane (o-Cb), respectively. The dyads consist a V-shaped BODIPY-(o-Cb)-BODIPY molecular array in which two BODIPY substituted onto adjacent carbon atoms the central o-Cb. In presence o-Cb unit, as an acceptor, significant fluorescence quenching was observed indicated photoinduced transfer (PET) had occurred from end-on to...

Electron accepting capability is greatly improved for B-phenylated tri-phenyl-o-carborane (1) through a favorable electronic interaction between the two adjoining phenyl-π* and cage carbon-σ* orbitals.

A variety of organotin complexes, containing the o-carboranylamino ligand (CabC,N), has been prepared by reaction LiCabC,N (1) with halides or tin tetrachloride. In this way, tetraorganotin compound (CabC,N)SnMe3 (2), triorganotin halide (CabC,N)SnR2X (3: R = Me, X Cl, 3a; Ph, 3b; Br, 3c), diorganotin dichloride (CabC,N)SnPhCl2 (4), and monoorganotin trichloride (CabC,N)SnCl3 (5) have synthesized characterized. 1H 119Sn NMR spectroscopy indicates that center in 2 is tetracoordinate, whereas...

Monodispersed ultrafine indium−tin oxide (ITO) particles were prepared in AOT-based reverse microemulsions with indium nitrate and tin chloride dissolved water droplets. The particle size distribution, calcination rate, chemical composition, electrical resistivity of pellets manufactured measured compared analogous measurements formed by bulk precipitation method. ITO showed a narrower faster lower resistivity. It was also confirmed that molecules are doped into the homogeneously rather than...

A series of group 13 main complexes with pi,sigma-type bonding interaction the formula [{(eta (5)-RC 2B 9H 9)(CH 2)(eta (1)-NMe 2)}MMe] (M = Al, R H 5, Me 6; Ga, 7, 8; In, 9, 10) was produced by reaction metal alkyls (MMe 3; M In) dicarbollylamine ligands, nido-8-R-7,8-C 10-7-(CH 2)NHMe 2 (R 1, 2). The reactions 1 and AlMe 3 in toluene initially afforded tetra-coordinated aluminum sigma,sigma-type interaction, (1)-RC 10)(CH 2)}AlMe 2] 3, 4), which readily underwent further methane...

We have synthesised mono-(NpCb) and bis-[(N,N-phenyl-1-naphthylamino)benzo]-o-caboranes (NpCbNp), which show anomalously intense aggregation-induced emission (AIE) at long wavelengths monomer short wavelengths. The actual concentration of the aggregator in AIE is very low, so absorption spectroscopy unsuitable for detecting small changes absorbance. Hence, to understand aggregation pattern, we employ excitation spectroscopy, since this method has excellent sensitivity compliance with...

Owing to their unique properties and biological activities, ionic liquids (ILs) have attracted research interest in pharmaceutics medicine. Hypoxia-inducible factor (HIF)- 1α is an attractive cancer drug target involved malignancy the hypoxic tumor microenvironment. Herein, we report inhibitory activity of ILs on HIF-1α pathway mechanism action. Substitution a dimethylamino group pyridinium reduced hypoxia-induced activation. It selectively inhibited viability human colon cell line HCT116,...

Abstract Our objective was to design and synthesize substituted o ‐carboranes carrying the 1,3,5‐ s ‐triazine units as potential boron neutron capture therapy agents. The preliminary results indicated that selective substitution successful, structural AB 2 (mono‐ ‐carboranyl‐1,3,5‐ ‐triazine) or A B (bis‐ type used starting point for generation of biologically active species. In first series, influence changes in central core unit investigated. Thus, a procedure sequential, derivatization...

Charge-compensated zinc metallocenes of types [(η3-C2B9H10)2Zn][(η1-NMe2)ZnEt]2 (5) and [{η3-(Me)C2B9H9}2Zn][(η1-NMe2)ZnEt]2 (6) were produced by reacting σ-/π-chelating aminoalkyl dicarbollides, 7-Me2N(H)CH2-7,8-C2B9H11 (1) 7-Me2N(H)CH2-8-Me-7,8-C2B9H10 (2), with diethylzinc. Zincocene 5 proved to be an excellent synthon for the formation dicarbollide-based σ-/π-type constrained Ru Ni complexes.

The cell growth inhibition profile of 2,4-(2-methyl-ortho-carboranyl)-4-(dimethylamino)-1,3,5-triazine (TAZ-6) was found to be similar that ICRF-193, a topoisomerase II inhibitor, as revealed by COMPARE analysis (correlation coefficient (r) = 0.724). Various mono- and di-ortho-carborane-substituted 1,3,5-triazines were synthesized based on the structure TAZ-6 tested for their ability inhibit activities topoisomerases I II. Among compounds synthesized, 3c, 4c, 4f completely inhibited activity...

A series of group 4 and 13 metal complexes coordinated to either a homo- or hetero-donor dicarbollyl ligand derived from N,N′- P,N-chelated ligands were synthesized characterized. Two tethered the type 7,8-(Me2NCH2)(μ-H)(Me2NCH2)-7,8-C2B9H10 (DcabNNH, 3) 7-PPh2-8-Me2NHCH2-7,8-C2B9H10 (DcabPNH, 6) prepared using standard deborination methods 1,2-(NMe2CH2)2-1,2-C2B10H10 (2) 1-PPh2-2-Me2NCH2-1,2-C2B10H10 (5), respectively. Subsequent reactions 3 with M(NMe2)4 (M = Ti, Zr) produced single...

The linear disilanes 1,2-bis(1'-R-o-carboranyl)-1,1,2,2-tetramethyl-1,2-disilane (R = H (2a), Me (2b), Ph (2c)) were prepared by reacting the lithium salt of 1-R-o-carborane (1) with 1,2-dichlorotetramethyldisilane. These (2) found to be useful precursors for synthesis a variety cyclic compounds. For instance, reaction dilithiodisilane 2a 1,2-dichlorotetramethyldisilane afforded four-membered compound 3,4-o-carboranylene-1,1,2,2-tetramethyl-1,2-disilacyclobutane (3). Further, whereas...

본 연구의 목적은 전지구 수문해석도구인 지표수문해석모형과 자료의 적용성을 평가하는데 있다. 이에 적정 지표수문해석모형을 선정하고 관측 댐 상류 유역을 대상으로 모형의 모의 능력을 평가하였다. 자료는 전 세계를 제공되는 기상 및 지형 자료를 이용하였으며, 불확실성을 평가하기 위해 자료별 생성되는 유출 결과의 정확도를 분석하였다. 또한 기간별 유출분석을 수행하여 활용방안을 마련하였다. 국내 기반으로 분석한 결과 국내의 복잡한 지형학적 특성에 대해서 신뢰성 높은 유출모의가 가능한 것으로 확인되었다. 자료에 대한 결과는 기상정보의 불확실성으로 인해 일단위 유출해석은 다소 부정확한 나타났으나, 분석에서는 단위 기간이 증가함에 따라 정확도가 향상되었으며, 10일 이상의 유출분석이 적절한 나타났다. 【The objective of this study is to evaluate the application Land Surface Model (LSM) and global spatial...

A method for preparing triazinyl-substituted carboranyl systems using 1,2-, 1,7-, and 1,12-C2B10H12 as cores [di(alkyl)amino]triazine substituents is described. sulfur-containing o-carboranyl cage compound was also incorporated into the 1,3,5-triazine network to generate new types of hybrid compounds having a thio-ether linkage. Within series synthesized compounds, one showed increased water solubility arising from effective camouflaging central p-carboranyl unit by polar functional groups...

A convenient method for o-carborane-substituted piperidines is described. Product compounds 5a, 5b, 5d, and 5e were found accumulate in B-16 melanoma cells with a significantly high level, although low cytotoxicity.

Morpholine- and bis(2-methoxyethyl)amine-substituted 1,3,5-triazine derivatives containing an alkoxy-o-carborane in the 6-position of triazine ring were successfully synthesized. The molecular structures methoxy- ethoxy-o-carboranyl-1,3,5-triazines established by X-ray crystallography. In vitro studies showed that methylene bridged morpholine- o-carboranyl-1,3,5-triazines accumulated to high levels B16 melanoma cells exhibited higher cytotoxicity than p-boronophenylalanine.