A5048573562- Nutrition and Health in Aging
- Gestational Diabetes Research and Management
- Diet and metabolism studies
- Birth, Development, and Health
- Cerebral Palsy and Movement Disorders
- Diabetes Management and Research
- Muscle Physiology and Disorders
- Diabetes Management and Education
- Ion channel regulation and function
- Neurotransmitter Receptor Influence on Behavior
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Migraine and Headache Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Neurogenetic and Muscular Disorders Research
- Mobile Health and mHealth Applications
- Bariatric Surgery and Outcomes
- Diabetes Treatment and Management
- Obesity, Physical Activity, Diet
- Frailty in Older Adults
- Body Composition Measurement Techniques
- Chronic Disease Management Strategies
- Air Quality and Health Impacts
- Adipokines, Inflammation, and Metabolic Diseases
- Metabolomics and Mass Spectrometry Studies
- IL-33, ST2, and ILC Pathways
German Center for Diabetes Research
2014-2025
Ludwig-Maximilians-Universität München
2016-2025
Deutsches Diabetes-Zentrum e.V.
2014-2025
Heinrich Heine University Düsseldorf
2014-2025
LMU Klinikum
2015-2024
Helmholtz Zentrum München
2015-2022
Università Campus Bio-Medico
2021
München Klinik
2012
Glostrup Hospital
2009
University of Copenhagen
2009
Background Information regarding the variability of metabolite levels over time in an individual is required to estimate reproducibility measurements. In intervention studies, it critical appropriately judge changes that are elicited by any kind intervention. The pre-analytic phase (collection, transport and sample processing) a particularly important component data quality multi-center studies. Methods Reliability metabolites (within-and between-person variance, intraclass correlation...
Abstract The gut microbiota has been linked to metabolic diseases. However, information on the microbiome of young adults at risk for type 2 diabetes (T2D) is lacking. aim this cross-sectional analysis was investigate whether insulin resistant women with previous gestational (pGDM), a high group T2D, differ in their stool from after normoglycemic pregnancy (controls). Bacterial communities were analyzed by high-throughput 16S rRNA gene sequencing using fecal samples 42 pGDM and 35 control...
To explore the association between knowledge on diabetes and glycemic control among patients with type 2 in Bangladesh.A cross-sectional study was conducted 515 attending a tertiary hospital Dhaka, Bangladesh. Trained interviewers were used to collect data socioeconomic status, time since onset of diabetes, co-morbidities, anthropometric measurements, blood tests, perceptions about causes, management, complications through face based structured questionnaire. Diabetes reported using...
Diabetes imposes a huge social and economic impact on nations. However, information the costs of treating managing diabetes in developing countries is limited. The aim this study was to estimate healthcare use expenditure for Bangladesh.We conducted matched case-control between January July 2014 among 591 adults with diagnosed mellitus (DMs) age-matched, sex-matched residence-matched persons without (non-DMs). We recruited DMs from consecutive patients non-DMs accompanying Bangladesh...
Eighty-five brain tumour patients were examined for further characteristics of tumour-associated headache. The overall prevalence headache in this population was 60%, but the sole symptom only 2%. Pain generally dull, moderate intensity, and not specifically localized. Nearly 40% met criteria tension-type An alteration pain with occurrence experienced by 82.5%, implying that pre-existing headaches different. classic mentioned International Classification Headache Disorders (worsening morning...
Mobile phone technologies including SMS (short message service) have been used to improve the delivery of health services in many countries. However, data on effects mobile technology patient outcomes resource-limited settings are limited. The aim this study therefore is measure impact a service treatment success newly diagnosed type 2 diabetes an urban area Bangladesh. This single-centred randomized controlled intervention trial (prospective) comparing standard-of-care with plus phone-based...
Abstract Background Sarcopenia is one of the most predominant musculoskeletal diseases elderly, defined as age-related progressive and generalized loss muscle mass with a simultaneous reduction in strength and/or function. Using metabolomics, we aimed to examine association between sarcopenia plasma metabolic profile sarcopenic patients, measured using targeted HPLC-MS/MS platform. Methods Plasma samples from 22 (17 men) hip fracture patients undergoing surgery (8 sarcopenic, age 81.4+6.3,...
Abstract Introduction Women with a history of gestational diabetes mellitus (GDM) are at high risk developing prediabetes or type 2 later in life. Recent studies have highlighted the regulation and function innate lymphoid cells (ILCs) metabolic homeostasis. However, multifactorial impact both overweight/obesity GDM on immunological profile circulating ILCs progression to not yet fully elucidated. Methods Blood samples from 42 women insulin-treated (GDMi), 33 without insulin treatment during...
Introduction Women with a history of gestational diabetes mellitus (GDM) are at high risk developing prediabetes or type 2 later in life. Recent studies have highlighted the regulation and function innate lymphoid cells (ILCs) metabolic homeostasis. However, multifactorial impact both overweight/obesity GDM on immunological profile circulating ILCs progression to not yet fully elucidated. Methods Blood samples from 42 women insulin-treated (GDMi), 33 without insulin treatment during...
Abstract Background The consensus definition of sarcopenia enables a clear diagnostic algorithm. syndrome can now also be coded in Germany (International Classification Diseases 10, ICD-10 GM 62.50). Compared to the estimated prevalence it is still significantly underdiagnosed. Current treatment options include resistance training and protein-rich diet, while pharmacological are missing. Objective Munich Sarcopenia Registry (MUSAR) aims raise awareness affected individuals. Additionally,...
The pathogenesis of type 2 diabetes (T2D) is still incompletely understood. In-depth phenotyping young individuals at risk for T2D can contribute to the understanding this process.The purpose study was metabolically characterize women with recent gestational (GDM), an at-risk cohort T2D.Participants were 147 consecutively recruited 3 16 months after pregnancy: who had GDM and a normoglycemic pregnancy (control subjects) in 2:1 ratio.This monocenter cross-sectional analysis (Prediction,...
Association between depression and diabetes amongst adults in Bangladesh: Hospital-based case-control study Methods A matched was conducted among 591 consecutive patients with attending a tertiary hospital Dhaka controls for age, sex area of residence without not related the index-case.Depression measured using Patient Health Questionnaire-9.Multivariate logistic regression performed to examine association diabetes.
Mobile phone SMS is increasingly used as a means of communication between patients and their healthcare providers in many countries the world. We investigated mobile use factors associated with willingness-to-pay (WTP) for diabetes among type 2 Bangladesh.As part randomized controlled study, 515 diabetes, socioeconomic status, use, WTP SMS, anthropometry HbA1c were measured. Multivariate regression was to identify WTP.The median (interquartile range [IQR]) 20 (45) Bangladesh Taka (BDT) (1...
Sarcopenia is a common geriatric syndrome and can lead to falls fragility fractures. It associated with decline of muscle fiber numbers size. Muscle biopsies the vastus lateralis were taken from thirty-two patients hip fracture (18 women 14 men; mean age: 82.2 ± 6.2 years). Serial cross sections skeletal labeled myosin heavy chain slow (fiber type-1) fast type-2) antibodies in order measure size, ratio percentage mixed types. The presence sarcopenia was defined according EWGSOP2 criteria by...
It was recently shown that the major allele of SLC30A8 (zinc transporter 8, ZnT8) single nucleotide polymorphism (SNP) rs13266634 associated with type 2 diabetes and reduced insulin secretion in non-diabetic relatives. Because its role beta-cell function, we hypothesized this candidate SNP may confer increased susceptibility for destruction 1 diabetes. We analyzed genotypes 874 patients 1021 control subjects. No difference genotype frequencies found between controls. Analysis respect to age...