A5065998049- Neuropeptides and Animal Physiology
- Olfactory and Sensory Function Studies
- Pain Mechanisms and Treatments
- Neuroscience of respiration and sleep
- Heart Rate Variability and Autonomic Control
- Neuroendocrine regulation and behavior
- Lymphoma Diagnosis and Treatment
- Biochemical effects in animals
- Myasthenia Gravis and Thymoma
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Receptor Mechanisms and Signaling
- Gastric Cancer Management and Outcomes
- Autoimmune Bullous Skin Diseases
- Metastasis and carcinoma case studies
- Medical Imaging and Pathology Studies
- Molecular spectroscopy and chirality
- Occupational and environmental lung diseases
- Trigeminal Neuralgia and Treatments
- Pleural and Pulmonary Diseases
- Biochemical Analysis and Sensing Techniques
- Gastrointestinal Tumor Research and Treatment
- RNA and protein synthesis mechanisms
- Urticaria and Related Conditions
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
National Institute of Advanced Industrial Science and Technology
2012-2025
Juntendo University Urayasu Hospital
2014-2024
The University of Queensland
2010-2024
Juntendo University
2004-2022
Syracuse University
2003-2021
Sapporo City General Hospital
2020
Fukuoka Tokushukai Hospital
2017
Health Sciences University of Hokkaido
2005-2014
Okinawa Institute of Science and Technology Graduate University
2013
Hokkaido University
2012
We describe five patients with underlying neoplasms in whom painful mucosal ulcerations and polymorphous skin lesions developed, usually progression to blistering eruptions on the trunk extremities. Histologic examination showed vacuolization of epidermal basal cells, keratinocyte necrosis, acantholysis. Immunofluorescence testing revealed atypical pemphigus-like autoantibodies perilesional epithelium serum from all patients. studied antigenic specificities by indirect immunofluorescence...
Salvileucalin B (2), having an unprecedented rearranged neoclerodane skeleton, was isolated from the aerial parts of Salvia leucantha Cav. (Labiatae) along with salvileucalin A (1). The absolute structures were elucidated by spectroscopic analysis, X-ray crystallographic and vibrational circular dichroism. Compound 2 represents a novel neoclerodane, characterized tricyclo[3.2.1.02,7]octane substructure incorporating exocyclic C-20 methylene 1. This molecule exerted cytotoxic activity against...
infection has been recognized as an urgent threat to antifungal drug resistance, and the Eagle effect of
The shape of motifs is important for RNA functions and deeply reflects the structure at supersecondary level, an intermediate level between secondary spatial structure. However, there currently no standardized classification system structures. Primary occupied conformations, accounting 73% nucleic acid backbone units, were found by extending concept protein code (SSSC) combined with conformational organic molecules. (SSCR) was introduced as a term each unit using letters P, S, T, D, denoting...
1. Electrical stimulation of the infra-orbital nerve and maxillary buccal gingiva caused an increase in ipsilateral lip blood flow a stimulus intensity-dependent manner anaesthetized cats. 2. The reflex vasodilator response was resistant to blockade by antimuscarinic (atropine), antiadrenergic (phentolamine propranolol) antihistaminergic (tripelennamine) but sensitive ganglionic blocking agent (hexamethonium). 3. unaffected section cervical sympathetic trunk facial root, completely abolished...
Abstract Background: Because mesothelioma initially progresses on the surface of pleura and peritoneum without forming masses, it has been difficult to diagnose at an early stage. It would be very useful identify a tumor marker that could used for screening enable more diagnoses made early, treatable Materials Methods: We had previously identified N-ERC/mesothelin as potential biomarker mesothelioma. In current work, we newly developed ELISA system gain data levels in various clinical...
Background The common grey wolf (Canis lupus) is found throughout the entire Northern hemisphere and preys on many kinds of mammals. urine contains a number volatile constituents that can potentially be used for predator–prey chemosignalling. Although put to practical use keep rabbits, rodents, deer so at bay, we are unaware any prior behavioural studies or chemical analyses regarding fear-inducing impact laboratory mice. Methodology/Principal Findings Three samples harvested different times...
In many species, older males are often preferred mates because they carry "good" genes that account for their viability. some animals, including mice, which rely heavily on chemical communication, there is indication an animal's age can be determined by its scent. order to identify the attractants in aged male mouse urine, and behavioral studies were performed. We herein show mice have higher levels of 3,4-dehydro-exo- brevicomin (DB), 2-sec-butyl-4,5-dihydrothiazole (BT),...
1. Electrical stimulation of the peripheral cut ends chorda tympani nerve proper (CTNP) and chorda‐lingual (CLN) elicited a blood flow increase in ipsilateral lower lip, tongue submandibular gland stimulus intensity‐dependent manner anaesthetized cats. 2. Pretreatment with hexamethonium (1.0 mg kg‐1, i.v.), an autonomic ganglionic blocker, significantly reduced CTNP‐induced increases all above three sites as well CLN‐induced but it had no effects on gland. 3. The CTNP stimulation‐induced lip...
The odd-even effect of chiral alkyl alcohols, (S)-CH(3)CHOHC(n)()H(2)(n)()(+1) (n = 2-8), in solution state has been observed spectroscopically for the first time. vibrational circular dichroism (VCD) bands at 1148 cm(-)(1) exhibit a clear effect. VCD (R)-(-)-2-hexanol correspond well to those predicted (population weighted). Density functional theory calculations indicate that most prevalent conformations are all-trans forms. is ascribed alternating terminal methyl motions chains relative...
The aim of the present study was to compare and characterize secretory vasodilator effects induced by chorda lingual nerve (CLN) stimulation (i.e., direct parasympathetic stimulation) reflex in submandibular gland (SMG) sympathectomized cats. increase blood flow salivary secretion response electrical central cut ends vagus inferior alveolar nerves, as well CLN at a site approximately 5 mm distal intersection SMG duct (site D) completely abolished section tympani (CTN). Neither nearly...