About
Contact & Profiles
Research Areas
- Epigenetics and DNA Methylation
- Inflammatory Bowel Disease
- Cardiovascular Disease and Adiposity
- Chronic Disease Management Strategies
- Cancer Immunotherapy and Biomarkers
- Health disparities and outcomes
- Digestive system and related health
- Nutrition, Genetics, and Disease
- Glutathione Transferases and Polymorphisms
- Health and Medical Studies
- Scientific Computing and Data Management
- demographic modeling and climate adaptation
- Medical Imaging Techniques and Applications
- IL-33, ST2, and ILC Pathways
- Cancer-related molecular mechanisms research
- Health, Environment, Cognitive Aging
- Air Quality and Health Impacts
- Global Health Care Issues
- Biomarkers in Disease Mechanisms
Second Affiliated Hospital of Zhejiang University
2024
Abstract This work aims to investigate how smoking exerts effect on the development of inflammatory bowel disease (IBD). A prospective cohort study and a Mendelian randomization are first conducted evaluate association between behaviors, smoking-related DNA methylation risks Crohn’s (CD) ulcerative colitis (UC). We then perform both genome-wide analysis co-localization validate observed associations. Compared never smoking, current previous habits associated with increased CD ( P = 7.09 × 10...
10.1038/s41467-024-44841-y
article
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Nature Communications
2024-01-18
10.1016/j.ebiom.2024.105443
article
EN
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EBioMedicine
2024-11-13
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