Han Zhang

ORCID: 0000-0002-8414-6378
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About
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Research Areas
  • Epigenetics and DNA Methylation
  • Inflammatory Bowel Disease
  • Cardiovascular Disease and Adiposity
  • Chronic Disease Management Strategies
  • Cancer Immunotherapy and Biomarkers
  • Health disparities and outcomes
  • Digestive system and related health
  • Nutrition, Genetics, and Disease
  • Glutathione Transferases and Polymorphisms
  • Health and Medical Studies
  • Scientific Computing and Data Management
  • demographic modeling and climate adaptation
  • Medical Imaging Techniques and Applications
  • IL-33, ST2, and ILC Pathways
  • Cancer-related molecular mechanisms research
  • Health, Environment, Cognitive Aging
  • Air Quality and Health Impacts
  • Global Health Care Issues
  • Biomarkers in Disease Mechanisms

Second Affiliated Hospital of Zhejiang University
2024

Abstract This work aims to investigate how smoking exerts effect on the development of inflammatory bowel disease (IBD). A prospective cohort study and a Mendelian randomization are first conducted evaluate association between behaviors, smoking-related DNA methylation risks Crohn’s (CD) ulcerative colitis (UC). We then perform both genome-wide analysis co-localization validate observed associations. Compared never smoking, current previous habits associated with increased CD ( P = 7.09 × 10...

10.1038/s41467-024-44841-y article EN cc-by Nature Communications 2024-01-18
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