A5025816313- Heparin-Induced Thrombocytopenia and Thrombosis
- Platelet Disorders and Treatments
- Intramuscular injections and effects
- Growth Hormone and Insulin-like Growth Factors
- Blood donation and transfusion practices
- Organ Donation and Transplantation
- Religion, Spirituality, and Psychology
- Cancer, Hypoxia, and Metabolism
- Muscle metabolism and nutrition
- High Altitude and Hypoxia
- Metabolism, Diabetes, and Cancer
- Blood properties and coagulation
Universitätsmedizin Greifswald
2019-2025
Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are based on a range of novel platforms, with adenovirus-based approaches (like ChAdOx1 nCov-19) being one them. Recently, complication SARS-CoV-2-targeted adenovirus vaccines has emerged: immune thrombocytopenia, either isolated, or accompanied by thrombosis (then termed VITT). This is characterized low platelet counts, and in the case VITT, also platelet-activating factor 4 antibodies reminiscent heparin-induced...
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a prothrombotic, heparin-induced (HIT)-mimicking, adverse reaction caused by platelet-activating anti-platelet factor 4 (PF4) antibodies that occurs rarely after adenovirus vector-based COVID-19 vaccination. Strength of PF4-dependent enzyme immunoassay (EIA) reactivity-judged optical density (OD) measurements-strongly predicts properties HIT in functional test. Whether similar relationship holds for VITT unknown.To evaluate...
Background and objectives Previous studies observed a transient increase in well‐being about one‐third of regular donors after blood donation. In addition, personal contact with donation seems to return rates. We were interested whether changes and/or the first impact rates first‐time ( FTD s). Materials methods First‐time randomized questionnaire group QG ), which questionnaires assessing had be filled in, or control CG was not contacted questionnaire. The complete same three times at day...
Abstract Objective Administration of human growth hormone (hGH) is prohibited in competitive sport and its detection an athlete’s sample triggers adverse analytical finding. However, the biological processes that are modulated by recombinant hGH not well characterized associated blood serum proteins may constitute new biomarkers for misuse. Methods Thirty-five recreational athletes were enrolled a study to investigate time- dose-dependent response protein levels administration. Participants...
Previous studies suggest that blood donation impacts donors' psychological state, with either positive or negative effects, such as feeling more energetic exhausted. It has not yet been described how long these effects last.This prospective cohort study consisted of a qualitative and quantitative part: (1) Psychological characteristics which changed after were identified by structured interviews regular whole donors (n = 42). Based on this, questionnaire addressing 7 dimensions was...