- Nanoplatforms for cancer theranostics
- Advanced Nanomaterials in Catalysis
- Nanoparticle-Based Drug Delivery
- Nanofabrication and Lithography Techniques
- Metamaterials and Metasurfaces Applications
- RNA modifications and cancer
- Cancer, Hypoxia, and Metabolism
- Photonic and Optical Devices
- Advanced Fiber Laser Technologies
- Extracellular vesicles in disease
- Advanced Antenna and Metasurface Technologies
- Orbital Angular Momentum in Optics
- Optical Coatings and Gratings
- Advanced biosensing and bioanalysis techniques
- Surface Modification and Superhydrophobicity
- Optical Network Technologies
- Optical measurement and interference techniques
- Immune cells in cancer
- Neural Networks and Reservoir Computing
- Digital Holography and Microscopy
- Cancer Research and Treatments
- Force Microscopy Techniques and Applications
- Advanced X-ray Imaging Techniques
- Random lasers and scattering media
- 3D Printing in Biomedical Research
Nanjing University
2021-2025
National Laboratory of Solid State Microstructures
2022-2025
Collaborative Innovation Center of Advanced Microstructures
2017-2025
Wuhan University
2020-2024
Second Affiliated Hospital of Zhengzhou University
2020-2022
Zhongnan Hospital of Wuhan University
2020-2022
Southern University of Science and Technology
2020-2022
Jinan University
2020-2022
First Affiliated Hospital of Zhengzhou University
2021
Academy of Medical Sciences
2021
Wide-angle imaging is an important function in photography and projection, but it also places high demands on the design of components a camera. To eliminate coma caused by focusing large-angle incident light, traditional wide-angle camera lenses are composed complex optical components. Here, we propose planar for with silicon nitride metalens array mounted CMOS image sensor. By carefully designing proper phase profiles metalenses intentionally introduced shifted terms, whole lens capable...
Abstract Optical encryption plays an increasingly important role in the field of information security owing to its parallel processing capability and low power consumption. Employing ultrathin metasurfaces optical has promoted miniaturization multifunctionality systems. Nevertheless, with few number degrees freedom (DoFs) multiplexed by single metasurface, both key space encoding are limited. To address this issue, we propose a high-security large-capacity scheme based on perfect...
A simple approach to wafer-scale self-cleaning antireflective hierarchical silicon structures is demonstrated. By employing the KOH etching and silver catalytic etching, pyramidal were generated on crystalline wafer, which exhibit strong antireflection superhydrophobic properties after fluorination. Furthermore, a flexible substrate was fabricated by transferring Si structure NOA 63 film with UV-assisted imprint lithography. This method of potential application in optical, optoelectronic,...
Intratumoral hypoxia significantly constrains the susceptibility of solid tumors to oxygen-dependent photodynamic therapy (PDT), and effort reverse such has achieved limited success date. Herein, we developed a novel engineered bacterial system capable targeting hypoxic tumor tissues efficiently mediating treatment these tumors. For this system, genetically Escherichia coli express catalase, after which explored an electrostatic adsorption approach link black phosphorus quantum dots (BPQDs)...
Microscopy is very important in research and industry, yet traditional optical microscopy suffers from the limited field-of-view (FOV) depth-of-field (DOF) high-resolution imaging. We demonstrate a simultaneous large FOV DOF microscope imaging technology based on chip-scale metalens device that implemented by SiNx array with co- cross-polarization multiplexed dual-phase design dispersive spectrum zoom effect. A 4-mm × obtained resolution of 1.74 μm 200 within wavelength range 450 to 510 nm,...
Replacing traditional refractive lenses with metalenses that have ultrathin and flat architecture could make imaging systems more compact. However, the space between lens image is usually dominating factor in determining bulkiness, it cannot be shortened just by using thinner lenses. Here, we propose a pancake metalens folds optical path at will metacavity consisting of spin-dependent bifacial metasurface mirror. We first verify asymmetric independent functions this metasurface, then...
Weyl medium has triggered remarkable interest owing to its nontrivial topological edge states in 3D photonic band structures that were mainly revealed as surface modes yet. It is undoubted the connection of two different media will give rise more fruitful physics at their interface, while they face extreme difficulty high-dimensional lattice matching. Here, we successfully demonstrate non-Hermitian interface complex synthetic parameter space, which implemented a loss-controlled silicon...
Abstract Quantitative phase imaging (QPI) based on the transport-of-intensity equation (TIE) is a powerful technique in label-free microscopy. The image stack required for successful TIE-QPI traditionally obtained by translating object or plane, and optical elements used conventional systems are usually bulky cumbersome. Stable compact methods capable of non-motion zooming can significantly facilitate applications that demand portability. Here, we propose method dispersive metalens. nature...
In combating cancer, ultrasound-triggered SDT manifests a wide range of promising applications, thus showing potential to overcome the shortcomings conventional PDT.
High doses of radiation can cause serious side effects and efficient radiosensitizers are urgently needed. To overcome this problem, we developed a biomimetic nanozyme system (CF) by coating pyrite (FeS
Coupling among closely packed waveguides is a common optical phenomenon, and plays an important role in routing integration. Unfortunately, this coupling property usually sensitive to the working wavelength structure features that hinder broadband robust functions. Here, we report new strategy utilizing artificial gauge field (AGF) engineer dispersion realize dispersionless with periodically bending modulation. The AGF-induced experimentally verified silicon waveguide platform, which already...
Abstract Optical wireless communication (OWC) stands out as one of the most promising technologies in sixth-generation (6G) mobile networks. The establishment high-quality optical links between transmitters and receivers plays a crucial role OWC performances. Here, by compact beam splitter composed metasurface fiber array, we proposed wide-angle (~120°) link scheme that can parallelly support up to 144 users. Utilizing high-speed module sources wavelength division multiplexing technique,...
In Chinese traditional medicine, quercetin (QT) plays a fundamental role in the treatment of asthma, as an anti-allergen and to lower blood pressure. Recent evidence suggests that QT can improve tumor radiosensitivity through multiple mechanisms. However, poor tissue targeting ability low water solubility limit its usefulness cancers. Herein, we designed novel drug delivery system (CQM) consisting inner loaded mesoporous silica nanoparticles (MSNs) outer cancer cell membranes (CM). The...
Abstract Owing to their ability rapidly proliferate in specific niches and amenability genetic manipulation, bacteria are frequently studied as potential diagnostic or therapeutic bioagents a range of pathological contexts. A sustained oxygen supply within solid tumors is essential order achieve positive radiotherapy (RT) outcomes, these intratumoral levels necessary facilitate RT‐induced reactive species (ROS) generation. In this study, genetically engineered variant the tumor‐targeting...
Sonodynamic therapy (SDT) possesses unique properties such as being minimally invasive, exhibiting low toxicity, well ability to impart the treatment in deep tissues, and hence has been extensively used. However, inherent defects water-soluble sonosensitizers can limit clinical application of SDT, tumor microenvironment (TME) further compromise effect a single SDT. To overcome these challenges, we have designed bionic nano-system (ECaC) by coating mesoporous calcium carbonate nanoparticles (CaCO
A method for decreasing the lateral size of conducting polymer patterns is demonstrated. Up to 15–70% shrinkage can be achieved based on nanoimprint lithography and isotropic plasma etching (see image). The direct assembly silver nanoparticles. This a simple route patterning high-resolution polymers.
In traditional Chinese medicine, dihydroartemisinin (DHA) is the focus of extensive attention because its unique activity with Fe2+ to produce reactive oxygen species (ROS) and promote apoptosis. this work, we designed a newfangled ink@hydrogel containing FeCl3, ink (Hu Kaiwen ink), agarose hydrogel create synergistic DHA in treatment cancer. When system irradiated under 1064 nm for few minutes, converts light heat hyperthermia causes reversible hydrolysis hydrogel. Then, Fe3+ quickly...
Introduction: The presence of cancer stem cells (CSCs) significantly limits the therapeutic efficacy radiotherapy (RT). Efficient elimination potential CSCs is crucial for enhancing effectiveness RT. Methods: In this study, we developed a biomimetic hybrid nano-system (PMC) composed MnCO 3 as inner core and platelet membrane (PM) outer shell. By exploiting specific recognition properties surface proteins, PMC enables precise targeting CSCs. Sonodynamic therapy (SDT) was employed using...
Transparent flow field visualization techniques play a critical role in engineering and scientific applications. They provide clear intuitive means to understand fluid dynamics its complex phenomena, such as laminar flow, turbulence, vortices. However, achieving fully two-dimensional quantitative of transparent fields under non-invasive conditions remains significant challenge. Here, we present an approach for by harnessing the synergistic effects dielectric metasurface array endowed with...
Abstract The transverse mode of a waveguide is an emerging degree freedom photons, and the nonlinear frequency conversion which essential to construct multi‐dimensional multiplexed photonic integrated circuits for high‐capacity optical communications. challenges modes are simultaneously fulfill phase‐matching conditions maximize overlap integral. In this work, scheme proposed achieve based on 2D ferroelectric domain engineering in material platform thin‐film lithium niobate (TFLN), where...
We present a new approach to fabricate arrays of silver nanoparticles (SNPs) on predefined positions by means electrochemical deposition (ECD) combined with nanoimprint lithography (NIL). The SNPs arrangement, especially the density can be tuned varying pattern design and preparation conditions. By this approach, various feature size down submicrometer fabricated over several square centimeters one substrate. readily extended other conductive substrates, which have potential applications in...