A5086447542- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Dialysis and Renal Disease Management
- Healthcare Systems and Reforms
- Chronic Kidney Disease and Diabetes
- COVID-19 and healthcare impacts
- Long-Term Effects of COVID-19
- Muscle and Compartmental Disorders
- Sepsis Diagnosis and Treatment
- Acute Kidney Injury Research
- Cancer Immunotherapy and Biomarkers
- Cannabis and Cannabinoid Research
- Diabetes Management and Education
- Global Public Health Policies and Epidemiology
- Health Systems, Economic Evaluations, Quality of Life
- Engineering and Information Technology
- Renal cell carcinoma treatment
- Nephrotoxicity and Medicinal Plants
- Virus-based gene therapy research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- COVID-19 Impact on Reproduction
- Heparin-Induced Thrombocytopenia and Thrombosis
- Sports and Physical Education Studies
- Vaccine Coverage and Hesitancy
- Educational Technology in Learning
University of New Mexico
2012-2024
Stanford University
2020-2023
Community Health Alliance
2023
Institute for Urban Indigenous Health
2023
Centro de Implantología Cirugía Oral y Maxilofacial
2021
Palo Alto University
2020-2021
Hospital General Universitario Gregorio Marañón
2012-2019
Probigua
2016-2018
Saint Peter's University Hospital
2016-2018
University of Córdoba
2017
Background Immune checkpoint inhibitor-associated acute kidney injury (ICPi-AKI) has emerged as an important toxicity among patients with cancer. Methods We collected data on 429 ICPi-AKI and control who received ICPis contemporaneously but did not develop from 30 sites in 10 countries. Multivariable logistic regression was used to identify predictors of its recovery. A multivariable Cox model estimate the effect ICPi rechallenge versus no survival following ICPi-AKI. Results occurred at a...
Data from hepatitis B[1][1] and influenza vaccination[2][2] studies indicate blunted foreshortened response to immunization in patients receiving dialysis, raising the worrisome possibility that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine may also yield lower
Background: Whether breakthrough SARS-CoV-2 infections after vaccination are related to the level of postvaccine circulating antibody is unclear. Objective: To determine longitudinal antibody-based response and risk for infection vaccination. Design: Prospective study. Setting: Nationwide sample from dialysis facilities. Patients: 4791 patients receiving dialysis. Measurements: Remainder plasma a laboratory processing routine monthly tests was used measure qualitative semiquantitative...
Objectives. Homeless individuals experience high rates of physical and mental illness, increased mortality, frequent hospitalizations. Respite care provides homeless with housing services allowing more complete recovery from illnesses stabilization chronic conditions. Methods. We investigated respite care’s impact on 225 hospitalized adults consecutively referred an urban public hospital during a 26-month period. The cohort was separated into 2 groups: (1) patients accepted the center (2)...
Patients on dialysis are at increased risk for COVID-19-related complications. However, a substantial fraction of patients belong to groups more likely be hesitant about vaccination.With the goal identifying strategies increase COVID-19 vaccine uptake among hemodialysis, we conducted nationwide acceptability survey, partnering with network distribute an anonymized English and Spanish language online survey in 150 randomly selected facilities United States. We used logistic regression...
Introduction. Endometrial carcinoma (EC) is the commonest gynecological cancer affecting women in Western populations. To predict patient risk, 2020 edition of World Health Organization (WHO) Classification Tumors Female Genital Tract stressed importance integrated histo-molecular classification disease. This survey analysis poses attention on most frequently used immunohistochemical and molecular markers adopted daily categorization ECs European laboratories.Methods. We analyzed data...
The aim of this study was to determine the incidence intra-abdominal hypertension (IAH) in patients with two or more categorized risk factors (CRF) for IAH, and their morbidity mortality during intensive care unit (ICU) stay. Prospective cohort carried out at a medical ICU. A total 151 were enrolled period 3 months. After ICU whole staff training, we conducted daily screening four CRF IAH based on World Society Abdominal Compartment Syndrome (WSACS) guidelines (namely, diminished abdominal...
Significance Statement As the SARS-CoV-2 pandemic enters a potentially endemic phase, with fewer community-level mitigation approaches, clinical parameters that indicate heightened infection risk can guide targeted provision of additional vaccine doses, or other protective measures, among patients receiving dialysis. In our prospective cohort study 3576 patients, three doses mRNA vaccines enhanced protection against during Omicron-dominant period in United States. Irrespective number...
Treatment of canine leishmaniasis (CanL) represents a challenge. Due to the high prevalence renal disease associated CanL, it is important find an effective drug that does not damage kidneys. Marbofloxacin has been shown be and well tolerated in non-azotemic dogs with leishmaniasis. To evaluate safety efficacy marbofloxacin decreased function, 28 suffering from chronic kidney (CKD) were treated oral at 2 mg/Kg/day for days. During treatment assessed by performing weekly physical exams,...
Abstract Background Patients receiving dialysis may mount impaired responses to COVID19 vaccination. Methods We report antibody response vaccination from 1140 patients without, and 493 with pre-vaccination SARS-CoV-2 RBD antibody. used commercially available assays (Siemens) test remainder plasma monthly in association date type, assess prevalence of absent total receptor binding antibody, or attenuated (index value < 10) semiquantitative domain IgG index values. Poisson regression...
Chronic kidney disease (CKD) is increasing worldwide, and the majority of CKD burden in low- middle-income countries (LMICs). However, there wide variability global access to care therapies such as dialysis transplantation. The challenges health professionals experience while providing LMICs have not been well described. goal this study elicit professionals' perceptions a resource-constrained environment, strategies for dealing with resource limitations, suggestions improving...
Assessing the evolution of SARS-CoV-2 immune response among patients receiving dialysis can define its durability in a highly clinically relevant context because share characteristics persons most susceptible to infection.To evaluate persistence receptor-binding domain (RBD) IgG seroprevalent dialysis.Prospective.Nationwide sample from facilities.2215 who had evidence infection as July 2020.Remainder plasma routine monthly laboratories was used measure semiquantitative RBD index value over 6...
Aims To estimate if chronic anticoagulant (CAC) treatment is associated with morbidity and mortality outcomes of patients hospitalized for SARS-CoV-2 infection. Methods In this European multicentric cohort study, we included 1186 whom 144 were on CAC (12.1%) positive coronavirus disease 2019 testing between 1 February 30 July 2020. The average effect (ATE) analysis a propensity score-matching (PSM) algorithm was used to the impact primary defined as in-hospital death, major minor bleeding...
Access to low-cost essential generic medicines is a critical health policy goal in low-and-middle income countries (LMICs). Guatemala an LMIC where there both limited availability and affordability of these medications. However, attitudes physicians pharmacy staff regarding generics, especially generics for non-communicable diseases (NCDs), have not been fully explored Guatemala.Semi-structured interviews with 30 12 several highland towns were conducted. Interview questions related...
Indigenous populations worldwide endure disparities in access to biomedical health care. This article suggests that institutional bureaucracy is an important and underexamined barrier care for indigenous Maya people Guatemala. Based on interviews, participant observation, seven years of experience with a non-governmental organization's patient advocacy program, we examine how institutions' administrative systems impede patients' abilities obtain specialty medical treatments. Particularly,...
Patients on dialysis vaccinated with the attenuated adenovirus SARS-CoV-2 vaccine might mount an impaired response to vaccination.We evaluated humoral vaccination among 2,099 fully patients receiving dialysis. We used commercially available assays (Siemens) assess prevalence of no or diminished COVID-19 by type. defined "no seroconversion" as lack change from negative positive in total RBD Ig antibody, detectable semiquantitative IgG antibody (index value <1) response", and a index <10...
Global health practitioners may feel frustration that current models of global research, delivery, and implementation are overly focused on specific interventions, slow to provide services in the field, relatively ill-equipped adapt local contexts. Adapting design principles from agile software development movement, we propose an analogous approach designing programs emphasizes tight integration between research implementation, early involvement ground-level workers program beneficiaries,...
Coronavirus disease 2019 (COVID-19) is public health concern across the world. Data on epidemiology among patients hemodialysis in Latin America and low- middle-income countries are limited.
Seroprevalence studies complement data on detected cases and attributed deaths in assessing the cumulative spread of SARS-CoV-2 virus.To estimate seroprevalence antibodies patients receiving dialysis adults US January 2021 before widespread introduction COVID-19 vaccines.This cross-sectional study used from third largest organization (US Renal Care), which has facilities located nationwide, to among dialysis. Remainder plasma (ie, that would have otherwise been discarded) all at Care 1 31,...
The burden of chronic, non-communicable diseases such as diabetes is growing rapidly in low- and middle-income countries. Implementing management programs for other chronic underserved populations thus a critical global health priority. However, there notable dearth shared programmatic outcomes data from treatment these settings.We describe our experiences non-governmental organization designing implementing type 2 program serving Maya indigenous people rural Guatemala. We detail the...
Chronic kidney disease (CKD) is an emerging public health priority in Central America. However, data on the prevalence of CKD Guatemala, America's most populous country, are limited, especially for rural communities.