A5034988755- Neuroendocrine regulation and behavior
- Human-Animal Interaction Studies
- Infant Development and Preterm Care
- Stress Responses and Cortisol
- Maternal Mental Health During Pregnancy and Postpartum
- Infant Health and Development
- Pregnancy and preeclampsia studies
- Birth, Development, and Health
New York University
2025
University of Massachusetts Amherst
2019
Embryonic development in many species, including case reports humans, can be temporarily halted before implantation during a process called diapause. Facultative diapause occurs under conditions of maternal metabolic stress such as nursing. While molecular mechanisms have been studied, natural inducing factor has yet to identified. Here, we show that oxytocin induces embryonic mice. We gestational delays were triggered nursing or optogenetic stimulation neurons simulating patterns. Mouse...
The ability of mothers to sensitively attune their maternal responses the needs developing young is fundamental a healthy mother-young relationship. biological mechanisms that govern how adjust caregiving dynamic changes in demands remain an open question. In present study, we examined whether monoamine levels, within discrete mesocorticolimbic structures involved cognitive and motivational processes key parenting, modulate this flexibility across postpartum period. study used Wistar-Kyoto...
Summary Parental care is required for offspring survival, because infants require nearly-continual oversight extensive periods. Parents must balance caretaking with their own and benefit from help provided by other experienced adults. We built a system 24/7 long-term monitoring of wild-type or oxytocin receptor knockout (OXTR-KO) mouse mothers (‘dams’) over litters. Some dams had high litter survival rates, but others consistently lost pups due to neglect hypothermia. Maternal in...