- Balance, Gait, and Falls Prevention
- Frailty in Older Adults
- Liver Disease Diagnosis and Treatment
- Reproductive tract infections research
- Liver Disease and Transplantation
- Pediatric health and respiratory diseases
- Education and Learning Interventions
- Genomics and Phylogenetic Studies
- Antioxidant Activity and Oxidative Stress
- Nutrition and Health in Aging
- Multi-Criteria Decision Making
- Adipokines, Inflammation, and Metabolic Diseases
- Cognitive Computing and Networks
- Pluripotent Stem Cells Research
- Pharmacological Effects of Natural Compounds
- Spacecraft and Cryogenic Technologies
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Image and Object Detection Techniques
- Education, Safety, and Science Studies
- Immunotherapy and Immune Responses
- Autophagy in Disease and Therapy
- Sirtuins and Resveratrol in Medicine
- Allergic Rhinitis and Sensitization
- Context-Aware Activity Recognition Systems
- Plant-based Medicinal Research
Severance Hospital
2022-2025
Yonsei University
2022-2025
Yonsei University Health System
2025
Korea University
2009-2024
University of Ulsan
2024
Asan Medical Center
2024
Ulsan College
2024
Wonkwang University
2015
Korea University of Science and Technology
2015
Korea Research Institute of Bioscience and Biotechnology
2015
Hospital falls are the most prevalent and fatal event in healthcare, posing significant risks to patient health outcomes institutional care quality. Real-time location system (RTLS) enables continuous tracking of location, providing a unique opportunity monitor changes physical activity, key factor related risk hospitals. This study is aimed at utilizing RTLS data capture dynamic movements, integrating it with clinical information through machine learning approach enhance in-hospital fall...
Pemetrexed, a multitarget antifolate used to treat malignant mesothelioma and non-small cell lung cancer (NSCLC), has been shown stimulate autophagy. In this study, we determined whether autophagy could be induced by pemetrexed simvastatin cotreatment in NSCLC cells. Furthermore, inhibition of drives apoptosis Malignant MSTO-211H A549 cells were treated with alone combination evaluate their effect on apoptosis. Cotreatment greater caspase-dependent than either drug 3-Methyladenine (3-MA),...
Abstract Hospital falls are the most prevalent adverse event in healthcare, posing significant risks to patient health outcomes and institutional care quality. The effectiveness of several fall prediction models currently use is limited by various clinical factors. This study explored efficacy merging real-time location system (RTLS) data with information enhance accuracy in-hospital predictions. model performances were compared based on data, RTLS a hybrid approach using evaluation metrics....
The effect of genistein on aortic atherosclerosis was studied by immunohistochemistry with RAM-11 and HHF-35 antibodies western blotting for matrix metalloproteinase-3 (MMP-3) in New Zealand White rabbits. After provocation hyperlipidemic diet, the rabbits were divided as diet group (HD), normal (ND) plus (HD+genistein) 4 half months. average cross sectional area atherosclerotic lesion 0.269 mm2 after provocation. progressed continuous (10.06 mm2) but increased mildly (0.997 mm2), decreased...
Chlamydophila pneumoniae is a Gram-negative intracellular obligate human pathogen and accounts for 5-10% of cases community-acquired pneumonia. However, isolating culturing this difficult, so there have been several studies searching new biomarkers its diagnosis. In study, we obtained immunogenic proteins C. KNIH-1 diagnosis using immunoproteomics. infection sera were selected the highest index value pneumoniae-specific IgG microimmunofluorescence (MIF). The detected protein spots in common...
ABSTRACT A bacterium designated M1-1 was isolated from the gills of a Korean rockfish, Sebastes schlegeli Hilgendorf, after high hydrostatic pressure processing. Studies 16S rRNA phylogeny and comparative genomics demonstrated that isolate belongs to Staphylococcus saprophyticus subsp. . Here, we report draft genome sequence S. (KACC 16562).
이 연구는 Strauss & Corbin (1998)의 근거이론 방법을 활용하여 수도권 지역의 초등학교라는 특정 맥락(context-bound) 하에서 알파세대의 특성에 따른 3주체의 상호작용 양상을 살펴보았다. 그리고 도출된 중범위(mid-range)를 바탕으로 일반 이론으로의 확장 가능성을 탐색하였다. 연구 결과, 기본 성향 및 특징, 사회성이 현상 전반에 대한 맥락적 조건이 되었으며, '교사 → 학생', '학부모 학부모', 교사' 관계 메커니즘별로 세대 변화에 양상이 드러났다.BR 결과를 단위 초등학교 내 교육 3주체 간의 효과적 상호작용을 위하여 다음과 같이 제언하였다. 첫째, 특성을 고려할 때, 과밀학급 해소를 위한 정책적 노력이 시급한 것으로 보인다. 둘째, 교사와 알파세대 학생 관점에서 학생들의 의사소통역량을 향상시킬 수 있는 학급경영 프로그램이 적극적으로 운영될 필요가 있다. 셋째, 학부모와 교육청 단위학교는 학부모들의 자녀 이해를 연수를 실시하여야 한다....
In March 2004, we experienced an outbreak of Chlamydia pneumoniae infection on islet Korea. order to assess the significance epidemic, performed a mass examination 137 students (7 - 16 years old; male, 69; female, 58) at school. The consisted questionnaire inquiring about respiratory symptoms, serum antibody test for C. using microimmunofluorescence (MIF) method and enzyme-linked immunosorbent assay (ELISA), nasopharyngeal swab tests detect organism by specific PCR cell culture. results...
Abstract Background The World Health Organization (WHO) has set targets to eliminate viral hepatitis, including hepatitis C virus (HCV) infection, by 2030. We present the results of in‐hospital Reflex tEsting ALarm‐C (REAL‐C) model, which incorporates reflex HCV RNA testing and sending alerts physicians. Methods conducted a retrospective study analysing data 1730 patients who newly tested positive for anti‐HCV between March 2020 June 2023. Three distinct periods were defined: pre‐REAL‐C ( n...
Cancer cells exhibit altered metabolism whereby glucose is preferentially utilized to produce lactate through aerobic glycolysis. The increase in production creates an acidic microenvironment that supports tumor progression and metastasis. Human small leucine zipper protein (sLZIP) involved the transcriptional regulation of genes related migration invasion prostate cancer. However, role sLZIP modulating cancer remains unknown. This study investigates whether regulates transcription...
ABSTRACT A bacterium, designated M2-6, was isolated from Korean ginseng, Panax ginseng C. A. Meyer, roots after high-hydrostatic-pressure processing. On the basis of 16 rRNA gene phylogeny, isolate presumptively identified as a Bacillus sp. Here we report draft genome sequence strain M2-6 (= KACC 16563).
Abstract Glycyrrhiza uralensis (licorice) is one of the most frequently prescribed ingredients in Oriental medicine and licorice root extracts have previously been shown to exhibit anti-carcinogenic activities. However, these harbor considerable quantities glycyrrhizin, which known exert anticarcinogenic activities induce severe hypokalemia hypertension. In this study, we evaluated effects hexane/ethanol extract (HEGU), lacks on metastatic characteristics 4T1 murine mammary carcinoma cells....
Purpose: Falls are the leading cause of injury among hospitalized patients, particularly older patients. We investigated association between serum phosphate (s-phosphate) levels and risk in-hospital falls. Patients Methods: This retrospective observational cohort study included all patients aged over 50 years who were admitted to Yongin Severance Hospital in South Korea January 2018 March 2021. Demographic, anthropometric, biochemical parameters recorded on admission. S-phosphate classified...
[Purpose]This study aims at suggesting policy implications for Korea's '2021 Development Plan the Elementary and Secondary Teacher Training System' by conducting comparative case studies of teacher training systems in Korea France. [Methods] This applies historical institutionalism approach investigates why how these have changed over past 40 years terms structure, system, actor. [Results] In Korea, most relevant factor change system was structural one, such as a decrease number school-age...
최근 신경망이 발달함에 따라 신경망을 이용한 암호분석 연구가 활발하게 진행되고 있다. 신경망 기반 암호분석은 키 복구 공격과 평문 공격이 그중 공격은 암호 키를 찾지 않고 암호문에 대응하는 평문을 복구하는 공격이다. 2012년에 DES의 성공적이라는 연구 결과가 발표되었다. 이는 연속함수와 가측함수의 근사 가능성을 보여주는 Universal Approximation Theorem(UAT)에 기반한다. 하지만 이산함수인 근사에 필요한 크기에 대한 정량적 분석의 부재와 학습 알고리즘의 수렴성에 과도하게 낙관적인 해석으로 결과를 신뢰할 근거가 부족하다. 본 논문에서는 신경망의 이산함수에 정량적으로 살펴보고 제안된 공격을 재연하고 비교한다. 마지막으로 부분 라운드 분석하여 공격의 한계를 분석한다.