A5046070998- Phytochemistry and Bioactive Compounds
- Genomics, phytochemicals, and oxidative stress
- Essential Oils and Antimicrobial Activity
- Ginger and Zingiberaceae research
- Natural product bioactivities and synthesis
- Pharmacological Effects of Natural Compounds
- Phytochemistry and Biological Activities
- Phytochemistry and biological activities of Ficus species
- Inflammatory Bowel Disease
- Ginkgo biloba and Cashew Applications
- Phytochemicals and Antioxidant Activities
- Tea Polyphenols and Effects
- Banana Cultivation and Research
- Microbial Metabolites in Food Biotechnology
- Biochemical Analysis and Sensing Techniques
- Ethnobotanical and Medicinal Plants Studies
- Environmental Sustainability and Education
- Chemical Safety and Risk Management
- Quality and Safety in Healthcare
- Microscopic Colitis
- Advances in Cucurbitaceae Research
- Science and Education Research
- Pharmacological Effects of Medicinal Plants
- Natural Antidiabetic Agents Studies
- Psidium guajava Extracts and Applications
Instituto Federal de Educação, Ciência e Tecnologia de Mato Grosso
2023
Universidade Estadual de Campinas (UNICAMP)
2007-2017
Fundação de Amparo à Ciência e Tecnologia de Pernambuco
2010
To evaluate the antioxidant activity of essential oil obtained from Rosmarinus officinalis (R. officinalis) in ethanol-induced gastric ulcer model vivo. The properties R. were evaluated against injury induced by absolute ethanol. Gastric tissues prepared to enzymatic assays. levels glutathione, lipid peroxides, and activities glutathione peroxidase, superoxide dismutase myeloperoxidase measured. Ethanol produced severe hemorrhagic lesions stomach with ulcerative lesion (140.2 ± 37.2) mm2. In...
Leaves and bark infusions Anacardium humile St. Hil. (Anacardiaceae), known as in Brazil “cajuzinho do cerrado”, have been used folk medicine an alternative treatment for ulcers gastritis. This study evaluated the gastroprotective activity of ethyl acetate extract leaves A. (AcF) mechanism involved this gastroprotection. Pretreatment concentrations (50, 100, 200 mg.kg−1) were administered by gavage. Following a 60 min. period, all rats orally 1 mL absolute ethanol. One hour after...
Rhizophora mangle, the red mangrove, has long been known as a traditional antiulcer medicine. The present work evaluated mechanisms of action involved in anti-ulcer properties mangle bark extracts. Gastroprotection was rodent experimental models (ethanol). To elucidate antisecretory and involvement NO, SH, mucus PGE2 were evaluated. acetic acid-induced gastric ulcer model, Western blotting assay (COX-1, COX-2 EGF) immunohistochemical localization HSP-70, PCNA also used to evaluate healing...
Ethanol-induced oxidative damage is commonly associated with the generation of reactive oxygen molecules, leading to stress. Considering that antioxidant activity an important mechanism action involved in cytoprotection, aim this work was evaluate properties alkaloid indigo (1) (2 mg/kg, P. O.), obtained from leaves Indigofera truxillensis Kunth (Fabaceae), on rat gastric mucosa submitted ethanol-induced (100%, 1 mL, O.) ulcer. Enzymatic assays and DNA fragmentation analysis were performed....
Rhizophora mangle , the red mangrove, has long been known as a traditional medicine. Its bark used astringent, antiseptic, hemostatic, with antifungic and antiulcerogenic properties. In this paper, we aimed to evaluate antioxidant properties of buthanolic fraction R. extract (RM) against experimental gastric ulcer in rats. Unib-Wh rats received pretreatment after induction injury absolute ethanol ischemia-reperfusion. Gastric tissues from both methods were prepared enzymatic assays, levels...
Abarema cochliacarpos (Gomes) Barneby & Grimes (Mimosaceae) is a species--in folk medicine of Lagarto city, Sergipe state, northeastern Brazil--reputed to heal gastric ulcer and gastritis.Chloroform (CE) methanolic (ME) extracts as well ethyl acetate fraction (AF), butanolic (AC) aqueous (AQF) the extract bark were evaluated against acute ulcer. The AC was selected assess its activity in healing gastroprotective effects via mucus secretion.The action CE ME fractions latter rodent...
Male Unib-WH rats were pretreated for two weeks with butanolic (BuOH) and ethyl acetate (EtOAc) fractions. Colitis was induced by rectal administration of TNBS, the treatment continued, animals sacrificed on day 7 after TNBS administration. Phytochemical studies performed in order to provide characterization tannins present bark R. mangle. Results showed that EtOAc fraction increased levels IL-10 (∗∗P < 0.01) diminished TNF-α (∗∗∗P 0.001) IL-6 0.01). BuOH reduced MPO activity TBARS 0.001);...
The present study evaluated the antiulcerogenic activity and mechanisms of aqueous (AqF 100 mg/kg) ethyl acetate (AcF 50 fractions from Indigofera truxillensis leaves. This dose was selected to assess its on ulcer healing action gastric acid mucus secretion, prostaglandin production antioxidant enzyme (superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) reductase (GSH-Rd)). Gastric induced by absolute ethanol. Antisecretory action, production, activities were for both fractions. AqF...
Royal Jelly (RJ) is widely consumed in diets throughout the world due to its beneficial effects: antioxidant, antitumor and anti‐inflammatory. We have investigated role of RJ development TNBS colitis mice. Colitis was induced by a rectal instillation at 0.1 mL per mouse. Intestine samples animals orally treated with (100, 150, 200 mg/kg) were collected for antioxidant assays (GSH GSH‐Px), proinflammatory protein quantification (COX‐2 NF‐ κ B), histological analyses. 100 mg/kg maintained GSH...
The hemolytic, anti-inflammatory and antinociceptive properties from hydrolyzed extract Agave sisalana Perrine ex Engelm., Asparagaceae (HEAS) was evaluated on classic inflammation models. Male Swiss mice male Wistars rats received HEAS (500 mg/kg) in two administration p.o. i.p. saline solution 0.9%. acid hydrolysis inhibited the hemolytic action of saponins due to retreat side chain sugar. treatment ear induced oedema by xylene with significantly reduced routes 13±1.5 10±0.63 mg,...
The present study evaluated the anti-inflammatory and analgesic properties of Agave sisalana Perrine in classic models inflammation pain. hexanic fraction A. (HFAS) was obtained by acid hydrolysis followed reflux. Anti-inflammatory were examined three acute mouse (xylene ear oedema, hind paw oedema pleurisy) a chronic model (granuloma cotton pellet). antinociceptive potential chemical (acetic-acid) thermal (tail-flick hot-plate test) When given orally, HFAS (5, 10, 25 50 mg/kg) reduced (p <...
A formação de professores é uma área crítica que exige apoio contínuo para desenvolver educadores capacitados e motivados. Neste contexto, o estudo teve como objetivo analisar a percepção inicial dos licenciandos bolsistas do Núcleo Ciências Naturais, composto pelos cursos Licenciatura em Biologia da Natureza com Habilitação Química, IFMT Campus Confresa sobre cumprimento objetivos Programa Incentivo à Docência, identificando aspectos sucesso áreas necessitam melhorias. Utilizando um...
A CIPA Unicamp, desde a última gestão, tem discutido sobre segurança dos usuários de laboratórios da com criação do grupo trabalho Laboratório Seguro, que elaborou o projeto “Laboratório Seguro – Preservando Vidas”. Nesse projeto, propõe medidas para universidade padronize e adeque as condições nos ensino pesquisa, principalmente os alunos (graduação, pós-graduação, extensão). O sido apresentado em colegiados unidades alertando necessidade mecanismos garantir laboratórios. Além propor,...