A5077776535- Bacterial Infections and Vaccines
- Neonatal Respiratory Health Research
- Vaccine Coverage and Hesitancy
- Influenza Virus Research Studies
- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Herpesvirus Infections and Treatments
- Congenital Diaphragmatic Hernia Studies
- Streptococcal Infections and Treatments
- Cytomegalovirus and herpesvirus research
- Virology and Viral Diseases
- Hepatitis Viruses Studies and Epidemiology
- Antibiotic Resistance in Bacteria
- Infectious Diseases and Tuberculosis
- Orthopedic Infections and Treatments
- Viral gastroenteritis research and epidemiology
- Infant Nutrition and Health
- Health, Medicine and Society
- Pediatric Urology and Nephrology Studies
- Healthcare Systems and Practices
- Central Venous Catheters and Hemodialysis
- Respiratory Support and Mechanisms
- Infant Development and Preterm Care
- Food Allergy and Anaphylaxis Research
- Infective Endocarditis Diagnosis and Management
Université de Rouen Normandie
2016-2025
Hôpital Charles-Nicolle
2015-2025
Inserm
1992-2025
Normandie Université
2022-2025
Société Française de Cardiologie
2017-2024
Centre Hospitalier Universitaire de Rouen
2007-2023
Biotherapy of Genetic Diseases, Inflammatory Disorders and Cancers
2019-2023
Centre de recherche en Epidémiologie et Santé des Populations
2014
Université Paris-Sud
2014
Hôpital Louis-Mourier
2014
Abstract Background The known relationship between the gestational age at maternal primary infection an outcome of congenital CMV is based on small, retrospective studies conducted 1980 and 2011. They reported that 32% 15% cases had sequelae following a in first second or third trimester, respectively. We aimed to revisit this prospectively 2011 2017, using accurate virological tools. Methods collected data women with infected child aged least 1 year time analysis. An determination timing...
The safety of the monoclonal antibody nirsevimab and effect on hospitalizations for respiratory syncytial virus (RSV)–associated lower tract infection when administered in healthy infants are unclear. Download a PDF Research Summary. In pragmatic trial, we randomly assigned, 1:1 ratio, who were 12 months age or younger, had been born at gestational least 29 weeks, entering their first RSV season France, Germany, United Kingdom to receive either single intramuscular injection standard care...
Background. About 10% of pediatric patients with invasive pneumococcal disease (IPD) die from the disease. Some primary immunodeficiencies (PIDs) are known to confer predisposition IPD. However, a systematic search for these PIDs has never been carried out in children presenting Methods. We prospectively identified cases IPD requiring hospitalization between 2005 and 2011 28 wards throughout France. was defined as positive culture, polymerase chain reaction result, and/or soluble antigen...
Approximately 20% of neonates with congenital cytomegalovirus (cCMV) develop long-term sequelae. The ability to accurately predict outcomes as early the neonatal period would help provide for appropriate parental counseling and treatment indications. With this study, we aimed identify predictive markers cCMV outcomes.
• As an infection, chickenpox is more severe in pregnant women than adults; it exposes the unborn child to three risks: congenital varicella syndrome, potentially neonatal varicella, and herpes zoster. In event of VZV contamination a non-immunized woman, first-line prophylaxis consists administration anti-VZV immunoglobulins during ten days following contact, at dose 0.5 1 ml /kg (IVL). Maternal seven before after birth can lead chickenpox; this situation justifies as soon possible (10...
SUMMARY This study was conducted during the 2008–2009 respiratory syncytial virus (RSV) season in France to compare hospitalization rates for bronchiolitis (RSV-confirmed and all types) between very preterm infants (<33 weeks' gestational age, WGA) without bronchopulmonary dysplasia full-term (39–41 matched date of birth, gender birth location, evaluate country-specific risk factors hospitalization. Data on hospitalizations were collected both retrospectively prospectively 498 (249 per...
The population structure of extraintestinal pathogenic Escherichia coli evolves over time, notably due to the emergence antibiotic-resistant clones such as ESBL-producing Enterobacteriaceae (ESBL-E).To analyse by WGS genetic diversity a large number ESBL-E isolated from urinary tract infections in children paediatric centres across France between 2014 and 2017 collected National Observatory febrile infection (FUTI) caused ESBL-E.A total 40 905 Enterobacteriaceae-positive urine cultures were...
Objectives We need studies assessing therapeutic options for oral relay in febrile urinary tract infection (FUTI) due to ESBL–producing Enterobacteriaceae (ESBL-E) children. Amoxicillin-clavulanate/cefixime (AC-cefixime) combination seems be a suitable option. sought describe the risk of recurrence at 1 month after end treatment FUTI ESBL-E according therapy used. Materials and methods retrospectively identified children <18 years who were included previous prospective observational...
Among 7578 cases of pediatric bacterial meningitis recorded in France (2001–2021), including 1313 neonatal cases, 23/7578 (0.3%) and 18/1313 (1.4%) were due to Citrobacter koseri. Median age was 11 days. About 63.6% patients hospitalized intensive care unit. Cerebral abscesses observed 77.8% the mortality rate 22.7%.
The optimal age for measles vaccination is an important health issue, since maternal antibodies may neutralize the vaccine antigen before a specific immune response develops, while delaying increase risk of complicated diseases in infants. However, impacts duration protection afforded by transplacental transfer antibodies: vaccination-induced disappear faster than disease-induced antibodies. In order to maintain against infants, it monitor dynamics this phenomenon vaccinated populations. To...
ABSTRACT Varicella is a widespread disease of childhood resulting from primary infection with varicella-zoster virus (VZV). The objective this study was to determine the kinetics decline maternal anti-VZV antibodies in French infants between birth and age 15 months order estimate duration passively acquired immunoglobulin G (IgG). This prospective multicenter conducted October 2005 January 2007 pediatric wards and/or emergency units seven hospitals scattered throughout country. level IgG...
Prematurity and bronchopulmonary dysplasia (BPD) affect long-term lung function. We studied the respiratory outcome of adolescents born very preterm controls from Etude EPIdémiologique sur les Petits Ages Gestationnels cohort analysed their current function in relation to asthma symptoms (categorised three age groups) birth. In models including BPD, at each confounding factors group, BPD preschool wheeze were only independent variables associated with FEV 1 . Preschool is an factor...