A5085062483- Liver Disease Diagnosis and Treatment
- Advanced biosensing and bioanalysis techniques
- Cardiovascular Health and Disease Prevention
- Biochemical effects in animals
- Antioxidants, Aging, Portulaca oleracea
- Phytoestrogen effects and research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diet, Metabolism, and Disease
- Nutritional Studies and Diet
- Biosensors and Analytical Detection
- DNA and Nucleic Acid Chemistry
- Liver Disease and Transplantation
- Machine Learning in Healthcare
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Risk Factors
- Genetic Associations and Epidemiology
- Analytical Chemistry and Sensors
- Nonlinear Photonic Systems
- Perovskite Materials and Applications
- Optical properties and cooling technologies in crystalline materials
- Trauma and Emergency Care Studies
- Ferroptosis and cancer prognosis
- Luminescence and Fluorescent Materials
- Maritime Ports and Logistics
- Peer-to-Peer Network Technologies
Tianjin University of Technology
2025
Peking University
2022-2024
Beijing Institute of Big Data Research
2023-2024
Yunnan University
2024
Beijing University of Agriculture
2024
Huazhong University of Science and Technology
2020-2023
University of Windsor
2023
Chongqing University of Education
2021-2022
Harbin Medical University
2022
Third Affiliated Hospital of Harbin Medical University
2022
This study aimed to estimate the prevalence of liver steatosis and fibrosis in general population populations with potential risk factors China, so as inform policies for screening management fatty disease high-risk populations.
Importance Epidemiologic studies on carotid atherosclerosis (CAS) based nationwide ultrasonography measurements can contribute to understanding the future risk of cardiovascular diseases and identifying high-risk populations, thereby proposing more targeted prevention treatment measures. Objectives To estimate prevalence CAS within general population China investigate its distribution among populations with potential factors variation across diverse geographic regions. Design, Setting,...
The Rotterdam computed tomography (CT) score was developed for prognostic purposes in traumatic brain injury (TBI).To examine the discrimination and prediction of CT case patients undergoing decompressive craniectomy (DC) TBI.The scans with worst findings before DC were scored according to classification. Mortality Glasgow Outcome Scale at end follow-up used as outcome measures. Unfavorable favorable outcomes defined by a 1 3 4 5, respectively. We binary logistic proportional odds regression...
The aim of this study is to evaluate the changes in soy isoflavones and peptides milk after lactic acid bacterial fermentation, explore positive effects fermented on an oxidative aging mouse model induced with D-galactose. We found that free soybean increased was by Lactobacillus fermentum CQPC04. vivo results indicated L. CQPC04-fermented enhanced organ index liver spleen, improved pathological morphology liver, skin. enzymatic activity glutathione peroxidase (GSH-Px), total superoxide...
Abstract A series of multiple logic circuits based on a single biomolecular platform is constructed to perform nonarithmetic and arithmetic functions, including 4-to-2 encoder, 1-to-2 demultiplexer, 1-to-4 multi-input OR gate. The encoder DNA circuit the equivalent sensory receptor reflex arc. They all function encode information from outside pathway (DNA or arc) into form that subsequent pathways can recognize utilize. Current molecular encoders are optical electrical signals as outputs,...
Abstract Objective To evaluate RSF and Cox models for mortality prediction of hemorrhagic stroke (HS) patients in intensive care unit (ICU). Methods In the training set, optimal were selected using five-fold cross-validation grid search method. test bootstrap method was used to validate. The area under curve(AUC) discrimination, Brier Score (BS) calibration, positive predictive value(PPV), negative value(NPV), F1 score combined compare. Results A total 2,990 HS included. For predicting 7-day...
In-hospital mortality, prolonged length of stay (LOS), and 30-day readmission are common outcomes in the intensive care unit (ICU). Traditional scoring systems machine learning models for predicting these usually ignore characteristics ICU data, which time-series forms. We aimed to use deep with selective combination three widely used predict outcomes.A retrospective cohort study was conducted on 40,083 patients from Medical Information Mart Intensive Care-IV (MIMIC-IV) database. Three...
Non-alcoholic fatty liver disease (NAFLD) and the newly proposed metabolic-associated (MAFLD) were each associated with subclinical atherosclerosis. However, there is limited evidence on risk of atherosclerosis in individuals who meet criteria for one but not other. We aimed to investigate associations MAFLD or NAFLD status site-specific multiple-site
After soymilk fermented by L. plantarum HFY09, the bound soybean isoflavones content was reduced, but free and peptides increased. In vivo results show that HFY09-fermented increased T-SOD, MDA, GSH-Px, GSH, CAT, NO in serum, liver, brain tissues of mice. The aforementioned also Col I hyaluronic acid, reduced contents III, H2O2, AGEs skin. upregulated Nrf2, HO-1, NOS1, NOS3, SOD1, SOD2, Nqol, Gclm expression liver spleen, NOS2 expression, SOD1 TIMP1, TIMP2 skin, downregulated MMP3, MMP9...
Single-nucleotide variation (SNV) detection plays significant roles in disease diagnosis and treatment. Generally, auxiliary probe, restricted design rules, complicated system, repeated experimental parameter optimization are needed to obtain satisfactory tradeoff between sensitivity selectivity for SNV discrimination, especially when different mutant sites need be distinguished. To overcome these limitations, we developed a universal, straightforward, relatively cheap discrimination...
Carotid plaque can progress into stroke, myocardial infarction, etc, which are major global causes of death. Evidence shows a significant increase in carotid incidence among patients with fatty liver disease. However, unlike the high detection rate disease, screening for asymptomatic population is not yet prevalent due to cost-effectiveness reasons, resulting large number undetected plaques, especially those disease.This study aimed combine advantages machine learning (ML) and logistic...
The study aimed to evaluate the effects of dietary folic acid (FA) on production performance laying hens, egg quality, and nutritional differences between eggs fortified with FA ordinary eggs. A total 288 26-week-old Hy-Line Brown hens (initial body weights 1.65 ± 0.10 kg) a similar weight genetic background were used. completely randomized design divided birds into control group three treatment groups. Each consisted six replicates, twelve chickens per replicate. Initially, all fed basal...
Non-alcoholic fatty liver disease (NAFLD) is one of the most common diseases worldwide. Currently, NAFLD prediction models are diagnostic based on cross-sectional data, which failed to provide early identification or clarify causal relationships. We aimed use time-series deep learning with longitudinal health checkup records predict onset in future, and update model stepwise by incorporating new achieve dynamic prediction.10,493 participants over 6 from Beijing MJ Health Screening Center...
Abstract Background Inferior vena cava tumor thrombus (IVCTT) invading the IVC wall majorly affects surgical method choice and prognosis in renal tumors. Enhanced multiparameteric MRI plays an important role preoperative evaluation. In this work, MRI-based diagnostic model for IVCTT was established so as to guide decisions. Methods Preoperative MR images of 165 cases tumors with were retrospectively analyzed, imaging indicators including morphology Mayo grade, diameter measurements, bland...
Introduction Previous studies based on a single measure of fasting plasma glucose (FPG) showed an inconsistent conclusion about the association between FPG and osteoporosis risk. Not accounting for time-varying cumulative average over time could bias true relation osteoporosis. Our study aims to investigate trajectories risk non-diabetic diabetic populations. Methods A total 18,313 participants who attended physical examinations during 2008–2018 were included. They free at their first...
Background: Acute high-altitude (HA) exposure results in blood pressure (BP) and cardiac function variations most subjects, some of whom suffer from acute mountain sickness (AMS). Several previous studies have found that cardiovascular indicators are potentially correlated with AMS. Objectives: This study aims to examine HA-induced adaptations AMS patients compare them healthy subjects. It also investigate the relationship between AMS, as well provide insightful information about prevention...
Abstract In recent years, the number of unmanned systems in world has been increasing. The emerging underwater platforms such as UUV are large number, small size, low speed and noise. future, a variety ocean combat missions will use platforms. existing methods for detecting vehicles mainly include sonar, magnetometer. Based on this, by referring to literatures, review research progress exploration at home abroad years. And compared with United States, Russia other countries system detection...
Breast cancer (BC) is the most prevalent in women worldwide. A systematic approach to BC treatment, comprising adjuvant and neoadjuvant chemotherapy (NAC), as well hormone therapy, forms foundation of disease’s therapeutic strategy. The extracellular matrix (ECM) a dynamic network that exerts robust biological effect on tumor microenvironment (TME), it highly regulated by several immunological components, such chemokines cytokines. It has been established ECM promotes development an...