Chunlin Yu

ORCID: 0000-0002-8567-069X
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About
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Research Areas
  • Marine Invertebrate Physiology and Ecology
  • Venomous Animal Envenomation and Studies
  • Marine Sponges and Natural Products
  • Copper-based nanomaterials and applications
  • Advanced Photocatalysis Techniques
  • ZnO doping and properties
  • Cancer-related molecular mechanisms research
  • MicroRNA in disease regulation
  • Catalytic Processes in Materials Science
  • Cancer Genomics and Diagnostics
  • Circular RNAs in diseases
  • Electronic and Structural Properties of Oxides
  • Marine Toxins and Detection Methods
  • Legume Nitrogen Fixing Symbiosis
  • Nonmelanoma Skin Cancer Studies
  • Healthcare and Venom Research
  • Connexins and lens biology
  • Neuroblastoma Research and Treatments
  • Asthma and respiratory diseases
  • Cutaneous Melanoma Detection and Management
  • Plant Stress Responses and Tolerance
  • Computational Drug Discovery Methods
  • Tendon Structure and Treatment
  • Seed Germination and Physiology
  • Machine Learning in Materials Science

Zhejiang University
2017-2025

Quzhou University
2024-2025

Ministry of Education
2025

Institute of Oceanology
2020-2024

Chinese Academy of Sciences
2021-2024

Qingdao National Laboratory for Marine Science and Technology
2021-2024

Sichuan Animal Science Academy
2020-2024

Sun Yat-sen University
2024

Liaoning Technical University
2023-2024

University of Chinese Academy of Sciences
2020-2023

Jellyfish envenomation is a common medical problem in many countries. However, the myotoxicity and effector molecules of scyphozoan venoms remain uninvestigated. Here, we present nematocyst venom from Nemopilema nomurai (NnNV), giant venomous China, for first time, using vivo models with inhibitors. NnNV was able to induce remarkable including significant muscle swelling, increasing content CK LDH serum, stimulating inflammation tissue, destroying structure tissue. In addition,...

10.1016/j.biopha.2022.113192 article EN Biomedicine & Pharmacotherapy 2022-05-26

Zein-based carriers are a promising delivery system for biomedical applications. However, few studies involve systematic investigation on their in vivo biocompatibility and immunogenicity.The objective of this study was to identify the immunogenicity, type immune response, systemic recall response zein nanoparticles administrated via different routes mice.Female Balb/c mice were selected as animal model paper. The effect particle size, dose inoculation immunogenicity systematically explored....

10.2147/ijn.s226466 article EN cc-by-nc International Journal of Nanomedicine 2019-12-01

Abstract Photoelectrochemical cells (PECs) for water splitting offer a promising way to convert solar energy into chemical energy. The electron transfer rate and surface‐catalyzed ability toward the hydrogen evolution reaction (HER) play key roles in efficiency of PEC splitting. In this work, photocathode based on Cu 2 O/Carbon film/NiCoB‐graphene oxide (Cu O/C/NiCoB−GO) heterostructure is fabricated. thickness‐controllable carbon film served as transport protective layer with favorable...

10.1002/celc.201801701 article EN ChemElectroChem 2019-01-23

The escalation of jellyfish stings has drawn attention to severe skin reactions, underscoring the necessity for novel treatments. This investigation assesses potential hydroxybenzoic acid derivatives, specifically protocatechuic (PCA) and gentisic (DHB), alleviating Nemopilema nomurai Nematocyst Venom (NnNV)-induced injuries. By employing an in vivo mouse model, study delves into therapeutic efficacy these compounds. Through a combination ELISA Western blot analyses, histological...

10.3390/md22050205 article EN cc-by Marine Drugs 2024-04-29

The Chengkou mountain chicken, a native Chinese poultry breed, holds significant importance in the country’s sector due to its delectable meat and robust stress tolerance. Muscle growth development are pivotal characteristics breeding, with muscle fiber during embryonic period crucial for determining inherent potential. Extensive evidence indicates that non-coding RNAs (ncRNAs) play regulatory role development. Among ncRNAs, circular (circRNAs), characterized by closed-loop structure, have...

10.3389/fvets.2024.1375042 article EN cc-by Frontiers in Veterinary Science 2024-05-30

The deactivation of ozone decomposition catalysts has been a bottleneck in their industrial application. As an efficient catalyst regeneration method, the liquid-phase method attracted wide attention due to its operability and universality. However, amount waste liquid generated by used is major drawback Therefore, we propose electrolytic for cyclic MnO

10.1021/acsami.4c09733 article EN ACS Applied Materials & Interfaces 2024-09-20

A hierarchical FeCo LDH/NiSe@NF nanowire–nanosheet heterostructure was fabricated via a two-step hydrothermal–electrodeposition strategy with excellent large-current-density OER activity and long-term stability.

10.1039/d4qi02426e article EN Inorganic Chemistry Frontiers 2024-01-01

Scyphozoan Nemopilema nomurai envenomation is an unresolved threat to human health in Asian waters. venom metalloproteinases show important toxicities skin damage and inflammation, but there still no purified protein for further studies. In this study, high proteinase activity fractions tentacle autolysis were isolated by ammonium sulfate precipitation, DEAE Sepharose Fast Flow, Superdex 75 chromatography successively. Purification was guided azocasein hydrolysis SDS-PAGE. The final products...

10.3389/fphar.2021.791847 article EN cc-by Frontiers in Pharmacology 2021-11-25

Jellyfish stings threaten people's health and even life in coastal areas worldwide. Nemopilema nomurai is one of the most dangerous jellyfish East Asian Marginal Seas, which not only hundreds thousands people every year but also assumed to be responsible for deaths by China. However, there no effective first-aid drug, such as antivenoms, treatment severe N. date. In this study, we prepared a antiserum from rabbits using inactivated toxins (NnTXs) isolated IgG type antivenom (IgG-AntiNnTXs)...

10.3390/ijms222312672 article EN International Journal of Molecular Sciences 2021-11-24

Jellyfish stings are a common issue globally, particularly in coastal areas the summer. Victims can suffer pain, itching, swelling, shock, and even death. Usually, hot water, vinegar, or alumen is used to treat normal symptoms of jellyfish sting. However, specific antivenom may be an effective treatment deal with severe stings. Cyanea nozakii often reach diameter 60 cm responsible for hundreds thousands per year Chinese waters. there has been no C. until now, so development this very...

10.3390/toxins13020165 article EN cc-by Toxins 2021-02-21

Download This Paper Open PDF in Browser Add to My Library Share: Permalink Using these links will ensure access this page indefinitely Copy URL DOI

10.2139/ssrn.4793643 preprint EN 2024-01-01

The spectral properties are the most prevalent continuous representation for characterizing transport phenomena and excitation responses, yet their accurate predictions remain a challenge due to inability perceive series correlations by existing machine learning (ML) models. Herein, ML model named cluster-based graph networks (CSGN) is developed based on dynamical theory of crystal lattices predict phonon density states (PDOS) spectrum materials. multiple atomic cluster constructed capture...

10.1002/advs.202406183 article EN cc-by Advanced Science 2024-10-18

Medical studies have found that tumor mutation burden (TMB) is positively correlated with the efficacy of immunotherapy for non-small cell lung cancer (NSCLC), and TMB value can be used to predict targeted therapy chemotherapy. However, calculation mainly depends on whole exon sequencing (WES) technology, which usually costs too much time expenses. To deal above problem, this paper correlation between slice images by taking advantage digital pathological slices commonly in clinic then...

10.7507/1001-5515.202304055 article EN PubMed 2023-10-25

Objective This study aimed to develop and assess the precision of a radiomics signature based on computed tomography imaging for predicting segmental chromosomal aberrations (SCAs) status at 1p36 11q23 in neuroblastoma. Methods Eighty-seven pediatric patients diagnosed with neuroblastoma confirmed genetic testing SCAs were enrolled randomly stratified into training set test set. Radiomics features extracted from 3-phase images analyzed using various statistical methods. An optimal was...

10.1097/rct.0000000000001564 article EN Journal of Computer Assisted Tomography 2023-11-27
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