A5101887302- Acupuncture Treatment Research Studies
- Gastrointestinal motility and disorders
- Infant Health and Development
- Diet and metabolism studies
- Anesthesia and Sedative Agents
- Gallbladder and Bile Duct Disorders
- Healthcare and Venom Research
- Anesthesia and Neurotoxicity Research
- Pancreatic and Hepatic Oncology Research
- Ion Channels and Receptors
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Anesthesia and Pain Management
- Vagus Nerve Stimulation Research
- Regulation of Appetite and Obesity
- Pancreatitis Pathology and Treatment
- Pain Management and Opioid Use
- RNA Interference and Gene Delivery
- Cancer-related Molecular Pathways
- Ferroptosis and cancer prognosis
- Cancer Treatment and Pharmacology
- Pain Mechanisms and Treatments
- Pediatric Pain Management Techniques
- Restless Legs Syndrome Research
- Biochemical Analysis and Sensing Techniques
- Pharmacological Effects of Natural Compounds
Nanjing General Hospital of Nanjing Military Command
2023-2025
Nanjing Medical University
2023-2025
Dalian Medical University
2010-2025
Second Affiliated Hospital of Dalian Medical University
2025
The First Affiliated Hospital, Sun Yat-sen University
2024-2025
Sun Yat-sen University
2012-2025
Union Hospital
2006-2024
Huazhong University of Science and Technology
2004-2024
Union Hospital
2007-2023
Shanghai Sixth People's Hospital
2023
ABSTRACT Objective We aimed to evaluate the differences in clinical features and lifestyle between Han ethnic minority populations Guangdong Province, China their impacts on ever‐growing burden of metabolic dysfunction‐associated steatotic liver disease (MASLD). Methods In this cross‐sectional investigation China, one most densely populated areas with imbalanced development, multistage stratified random sampling was used. Demographic, socioeconomic, data participants were collected....
Abstract Brain endothelial cell (bEC) dysfunction is the main factor of blood-brain barrier (BBB) breakdown, which triggers a vicious cycle aggravating traumatic brain injury (TBI) pathogenesis. Previous studies have revealed that neutrophil extracellular traps (NETs) released by neutrophils can lead to BBB disruption, but there lack research on underlying mechanisms after TBI. Here, excessive NETs were found in both contused tissue and circulation following We could activate TLR4/NF-κB...
Nausea, an unpleasant symptom of diabetic gastroparesis (DMGP), has been reported to be alleviated by needleless transcutaneous electrical acupuncture (TEA). Our study was designed utilize electroencephalography (EEG) and electrogastrography (EGG) recordings investigate the central peripheral responses TEA in treatment nausea DMGP patients.Eleven subjects underwent simultaneous EEG EGG testing while grading severity following 30-minute intervals of: (1) baseline, (2) visual stimulation (VS)...
Phosphatase and tensin homolog deleted on chromosome ten (PTEN) is a dual lipid protein phosphatase. Multiple mechanisms contributing to the regulation of PTEN levels have been identified thus far, including post-translational modifications, epigenetic mechanisms, transcriptional mechanisms. In present study, we ubiquitin-specific peptidase 22 (USP22) as novel deubiquitination-modifying enzyme PTEN. Furthermore, by inducing deubiquitination inhibiting degradation PTEN, USP22 could induce...
Abstract Background Gastric electrical stimulation ( GES ) has been suggested as a potential treatment for patients with gastric motility disorders. The aim of this study was to examine the effects and mechanisms on visceral pain in awaken rats. Methods Under anesthesia, acetic acid injected into submucosal layer stomach wall S prague– D awley SD male Each rat chronically placed an intragastric balloon two pairs electrodes serosa at neck muscles electromyography EMG recordings respectively....
Postoperative pancreatic fistula (POPF) represents the most common complication following pancreaticoduodenectomy (PD). Predictive models are needed to select patients with a high risk of POPF. This study was aimed establish an effective predictive nomogram for POPF PD.
Gastric electrical stimulation (GES) has been used to treat obesity with unclear mechanisms and limited parameter ranges. This study explores effects of GES parameters on ventral medial hypothalamic (VMH) activity, feeding, body weight in diet-induced obese (DIO) rats. For experiment 1, discharge rates were recorded 39 gastric distension-responsive (GD-R) neurons 12 DIO Basal compared under using varied pulse amplitudes, widths, frequencies, train-on times. 2, a crossover 16 rats measured...
The aim of this study was to determine the most effective and efficient anti-emetic parameters short-pulse gastric electrical stimulation (GES) in dogs. Seven female beagle dogs implanted with four pairs electrodes were studied eight randomized sessions (saline, vasopressin, six GES different parameters). Each session consisted 20-min recordings slow waves symptoms. In 1 2, saline respectively, infused during second period. protocol other same as 2 except that continuously applied. It found...
The aims of this study were to determine optimal pacing parameters electrical stimulation on different gut segments and investigate effects possible mechanisms gastrointestinal slow waves. Twelve female hound-mix dogs used in study. A total six pairs electrodes implanted the stomach, duodenum, ascending colon. Bilateral truncal vagotomy was performed dogs. One experiment designed frequency entrainment Another modulatory vagal sympathetic pathways pacing. waves 4.88 +/- 0.23 cpm (range, 4-6...
The incidence of gastrointestinal stromal tumors (GISTs) located in the colon is rare. Current studies mainly focus on case reports for colonic GISTs. Therefore, a population-based analysis was useful to guide clinical treatment strategy. patients were selected from 2000 2015 based Surveillance, Epidemiology, and End Results (SEER) database. Patients' demographics, tumor characteristics, incidence, treatment, survival retrieved analysis. 249 cases GISTs collected. male-female ratio close 1 :...
Abstract Background Needleless transcutaneous electroacupuncture ( TEA ) improves nausea and myoelectrical activity in diabetic gastroparesis GP ). Synchronized STEA ), which combines synchronized breathing with , is more potent than enhancing vagal healthy subjects. Aims To investigate whether symptoms, electrogastrogram EGG idiopathic IGP Methods Eighteen subjects underwent 2 randomized visits (sham at non‐acupoints or real acupoints) consisted of a 30‐minute baseline, an Ensure challenge...
Postoperative complications after pancreatectomy are a challenging problem due to their high incidence and serious consequences. The majority of studies have focused on specific complication, but data predictors overall postoperative (OPCs) limited.The patients who underwent at single institute between 2017 2019 were analyzed retrospectively. Univariate multivariate logistic regression used investigate the outcomes interest. Clavien-Dindo classification comprehensive complication index (CCI)...
OBJECTIVE: To investigate the effects of acute and chronic partial restraint stress (PRS) on visceral sensi‐tivity to colorectal distention neuroendocrine response in rats. METHODS: Male Sprague–Dawley rats were used this study. The abdominal withdrawal reflex score was assessed before stress, immediately after or PRS, 7 days first stress. plasma levels corticosterone (CORT) adrenocorticotropic hormone (ACTH) detected by radioimmunoassay at different time points. RESULTS: scores with PRS...