A5072597827- Childhood Cancer Survivors' Quality of Life
- Acute Lymphoblastic Leukemia research
- COVID-19 and Mental Health
- Advances in Oncology and Radiotherapy
- Palliative Care and End-of-Life Issues
- Patient-Provider Communication in Healthcare
- COVID-19 Pandemic Impacts
- Pharmaceutical Practices and Patient Outcomes
- Global Cancer Incidence and Screening
- CAR-T cell therapy research
- Autoimmune and Inflammatory Disorders
- Prenatal Screening and Diagnostics
- Neutropenia and Cancer Infections
- Adolescent and Pediatric Healthcare
- COVID-19 and healthcare impacts
- Pharmaceutical studies and practices
- Global Health and Surgery
- Lymphoma Diagnosis and Treatment
- Sarcoidosis and Beryllium Toxicity Research
- Histiocytic Disorders and Treatments
- Viral-associated cancers and disorders
- Family Support in Illness
Addis Ababa University
2020-2025
Tikur Anbessa Hospital
2021
This study explores sources of stress, conditions that help reduce stress levels and coping strategies among parents children with cancer receiving chemotherapy at Tikur Anbessa Specialized Hospital (TASH) in Ethiopia.
T‐cell/histiocyte‐rich large B‐cell lymphoma (THRLBCL) is a rare and aggressive subtype of diffuse (DLBCL) that uncommon in children. Here, we present the case an 8‐year‐old male with 3‐month history low‐grade intermittent fever, significant weight loss, loss appetite, progressive abdominal swelling. Examination revealed splenomegaly palpable midabdominal mass, laboratory findings showing bicytopenia. Imaging demonstrated hepatosplenomegaly, hypodense liver spleen lesions, mesenteric...
Abstract Background COVID-19, the disease caused by new coronavirus SARS-CoV-2 is among most obscure global pandemics resulting in diverse health and economic disruptions. It adversely affects routine care delivery service uptake patients. However, its impact on care-seeking behaviour largely unknown Ethiopia. Objective This study was to determine of pandemic patients with chronic condition at Tikur Anbessa Specialized hospital Addis Ababa. Methods A cross-sectional hospital-based survey...
Background . Even though medications play a major role in the cure, palliation, and inhibition of disease, they also expose patients to drug-related problems. Drug-related problems are frequent may result reduced quality life, morbidity, mortality. Objectives The study was aimed identify, characterize, resolve Pediatric Hematology/Oncology ward Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Methods A prospective observational conducted from 25 June October 2018 assess DRPs on...
Abstract Purpose A considerable barrier to global pediatric oncology efforts has been the scarcity and even absence of trained professionals in many low‐ middle‐income countries, where majority children with cancer reside. In 2013, no dedicated hematology‐oncology (PHO) programs existed Ethiopia despite estimated annual incidence 6000‐12000 cases. The Aslan Project initiative was established fill this gap order improve care Ethiopia. major objective increase subspecialty PHO‐trained...
Introduction The maintenance phase of acute lymphoblastic leukemia treatment is the final and longest stage treatment, mainly focused on antimetabolite therapy. This essential to eliminate residual leukemic clones prevent relapse. However, dose-limiting hematotoxicity a major problem during this resulting in dose reduction or discontinuation. Objective In cohort study, clinical features risk factors hematological toxicity were analyzed pediatric patients from Ethiopia. Methods A total 160...
L-asparaginase is a vital component for the treatment of childhood acute lymphoblastic leukemia (ALL); however, hypersensitivity reactions and hepatotoxicity hinder its anti-neoplastic efficacy. Previous reports indicated that genetic variants in CNOT3, GRIA1, NFATC2 genes might be associated with PNPLA3 liver function.In this study, it was investigated whether association also exists pediatric ALL cohort from Ethiopia.Three GRIA1 rs4958351, CNOT3 rs73062673, rs6021191 were genotyped 160...
Introduction: Genetic variation in the thiopurine S-methyltransferase (TPMT) gene by and large predicts variability 6-mercaptopurine (6-MP) related toxicities. However, some individuals without genetic variants TPMT still develop toxicity that necessitates 6-MP dose reduction or interruption. of other genes pathway have been linked to toxicities previously. Objective: The aim this study was evaluate effect ITPA, TPMT, NUDT15, XDH, ABCB1 on patients with acute lymphoblastic leukemia (ALL)...
Abstract Background Preferences for parent involvement in treatment decision-making vary between passive, collaborative, and active, depending on different factors. This study explores the parental role pediatric cancer (TDM) Ethiopia identifies factors which determine this role. Methods The combines a cross-sectional survey phenomenological interview study. In total 167 parents of children with participated survey. Control Preference Scale Pediatrics (CPS-P) Krantz Health Opinion Survey...