- Lipoproteins and Cardiovascular Health
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Acute Myocardial Infarction Research
- Heart Failure Treatment and Management
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac pacing and defibrillation studies
- Health and Lifestyle Studies
- Takotsubo Cardiomyopathy and Associated Phenomena
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Mechanical Circulatory Support Devices
- Cardiac electrophysiology and arrhythmias
- Orthopaedic implants and arthroplasty
- Cardiac Arrhythmias and Treatments
- Trypanosoma species research and implications
- Cardiac Health and Mental Health
- Streptococcal Infections and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Pericarditis and Cardiac Tamponade
- Cardiac Valve Diseases and Treatments
- Coronary Interventions and Diagnostics
- Blood Pressure and Hypertension Studies
- Mitochondrial Function and Pathology
Institute of Cardiology
2012-2023
Digestive Care (United States)
2021
Clínica Santa María
2021
Universidad Pontificia Bolivariana
2013-2021
Population Health Research Institute
2017
McMaster University
2017
We evaluated the relationship of renal function and ischaemic bleeding risk as well efficacy safety ticagrelor in stable patients with prior myocardial infarction (MI). Patients a history MI 1–3 years from PEGASUS-TIMI 54 were stratified based on estimated glomerular filtration rate (eGFR), <60 mL/min/1.73 m2 pre-specified for analysis effect primary composite cardiovascular death, MI, or stroke (major adverse events, MACE) endpoint TIMI major bleeding. Of 20 898 patients, those eGFR (N =...
Por medio de la teoría los sistemas dinámicos es posible cuantificar el estado y evolución dinámicos; dinámica caótica cardiaca ha sido evaluada desde geometría fractal realizando investigaciones clínicas con infarto agudo miocardio y, por otro lado, ley entropía desarrollando un diagnóstico aplicación clínica.
 Se seleccionaron 150 holters, 50 diagnosticados dentro límites normalidad, según clínico convencional otras enfermedades. para cada paciente se generó secuencia valores...
Risk stratification in cardiac surgery significantly impacts outcome. This study seeks to define whether there is an independent association between the preoperative serum level of hemoglobin (Hb), leukocyte count (LEUCO), high sensitivity C-reactive protein (hsCRP), or B-type natriuretic peptide (BNP) and postoperative morbidity mortality surgery.Prospective, analytic cohort study, with 554 adult patients undergoing a tertiary cardiovascular hospital followed up for 12 months. The was...
Resumo Fundamento Múltiplos sistemas de pontuação têm sido elaborados para calcular o risco eventos cardiovasculares adversos maiores (MACE) em pacientes com dor no peito. Não há dados que avaliem se escore HEART tem um desempenho superior a TIMI e GRACE predição MACE, especialmente na era troponina I alta sensibilidade uma população exclusivamente latino-americana. Objetivo Comparar dos escores HEART, MACE 30 dias acompanhamento, atendidos peito departamento emergência. Métodos Os foram...
Kounis syndrome (KS) is a rare characterized by the co-occurrence of acute coronary syndromes in setting mast cell and platelet activation response to hypersensitivity reactions. It can be manifested as vasospasms, myocardial infarction, or stent thrombosis triggered drugs, vaccines, foods, stents, insect bites. life-threatening condition that needs adequately recognized for early diagnosis appropriate treatment. In this case report, we present 71-year-old patient with history arterial...
Background A proposed cause of dyspnea induced by ticagrelor is an increase in adenosine blood levels. Because caffeine antagonist, it can potentially improve drug tolerability with regard to dyspnea. Furthermore, association between and cardiovascular events clinical interest. Methods Results This prespecified analysis used data from the PEGASUS TIMI 54 (Prevention Cardiovascular Events Patients With Prior Heart Attack Using Ticagrelor Compared Placebo on a Aspirin-Thrombolysis Myocardial...
European Society of Cardiology (ESC) guidelines for the management acute coronary syndromes in patients presenting without persistent ST-segment elevation (NSTEMI) recommend Intensive Care Unit (ICU) surveillance during first 24-48 h. Interestingly, in-hospital mortality NSTEMI has consistently decreased, giving some option to be managed general hospital wards. The ACTION ICU score been proposed identify high-risk with and guide selective risk-based need care.To evaluate usefulness predict...
Abstract Background Abiraterone is a medication frequently used for metastatic castrate-resistant prostate cancer. We report case of non-sustained episodes TdP associated with severe hypokalemia due to androgen-deprivation therapy. Few presentations describe this association; the novelty lies in potentially lethal cardiovascular events among cancer patients receiving hormonal Case presentation A 70-year-old male presented recurrent syncope without prodrome. ECG revealed frequent ventricular...
Stress cardiomyopathy is a form of acute and transient myocardial injury characterized by regional systolic dysfunction.1 Takotsubo (TTC) stress with specific pattern dysfunction. It classically induced emotional or physical often mimics an infarction.1,2 Regional wall abnormalities in TTC typically compromise the left ventricle (LV), extend beyond coronary artery supply region, have apical circumferential dysfunction that results ballooning LV during systole.
Objectives: Ticagrelor reduced the risk of CV death, MI or stroke in stable patients with prior PEGASUS-TIMI 54. We investigated consistency ticagrelor’s efficacy and safety over time quantified magnitude benefit who tolerated ticagrelor for first year, analogous to clinical situation extending therapy after 1 year. Methods: 54 randomized pts a (median 1.7 yrs randomization) 90 mg twice daily, 60 daily placebo. The rate CVD/MI/stroke TIMI major bleeding were analyzed pooled doses compared...
Multiple treatment comparison meta-analyses are systematic reviews that allow to make direct or indirect comparisons of different interventions from the data collection results randomized clinical trials, grouping them in a common outcome conglomerate which is expressed quantitatively. Other names given network meta-analyses, mixed meta-analyses. The use several treatments allows greater estimation intervention effect. This guide for physician more accurate decisions and apply better care...
Si bien se ha avanzado de manera exponencial en el tratamiento la falla cardiaca, 1-10% los pacientes progresa a cardiaca avanzada, sindrome caracterizado por deterioro clinico continuo, caquexia, intolerancia titulacion medicacion, resistencia diureticos y episodios frecuentes descompensacion; estadio cual trasplante cardiaco ortotopico es manejo eleccion.
Slipped capital femoral epiphysis (SCFE) is a severe and catastrophic disorder that affects the hips of adolescents. Many reports about surgical procedures to treat this condition have been published, but our knowledge, there are no published results treatment in Latin American patients. This study describes clinical radiological modified Dunn procedure with approach described by Ganz mild SCFE cohort Colombian pediatric patients.We retrospectively analyzed 21 patients (22 hips) treated...
Objetivo: caracterizar desde el punto de vista microbiológico las infecciones periprotesicas (IP) los pacientes sometidos a remplazo articular rodilla o cadera, en la IPS universitaria Clínica León XIII, y evidenciar patrones más comunes resistencia antibióticos, periodo 2015-2018. Metodología: se recolectó información 25 llevados cadera universitaria, sede durante 2015-2018, que desarrollaron IP. Se obtuvo sobre características demográfica, clínicas (según antibiograma), criterios usados...