A5082904170- COVID-19 Clinical Research Studies
- Innovations in Medical Education
- Adipokines, Inflammation, and Metabolic Diseases
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- Pain Mechanisms and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Medical Education and Admissions
- Autoimmune and Inflammatory Disorders Research
- Clostridium difficile and Clostridium perfringens research
- Psoriasis: Treatment and Pathogenesis
- Hedgehog Signaling Pathway Studies
- Spondyloarthritis Studies and Treatments
- Cancer-related Molecular Pathways
- Diabetic Foot Ulcer Assessment and Management
- Epilepsy research and treatment
- Cardiovascular Disease and Adiposity
- EEG and Brain-Computer Interfaces
- Alcohol Consumption and Health Effects
- Diabetes Treatment and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Chemokine receptors and signaling
- Problem and Project Based Learning
- Respiratory and Cough-Related Research
- Neuroscience and Neuropharmacology Research
University of Bisha
2015-2025
University of Dundee
2024
Armed Forces Hospital
2024
King Khalid University
2024
King Fahd Medical City
2012-2022
King Abdullah Medical City
2020-2022
Arabian Gulf University
2022
Vanderbilt University Medical Center
2022
Ministry of Health
2020-2021
Abstract Background Distractor efficiency (DE) of multiple-choice questions (MCQs) responses is a component the psychometric analysis used by examiners to evaluate distractors’ credibility and functionality. This study was conducted impact DE on difficulty discrimination indices. Methods cross-sectional from April June 2023. It utilizes final exam Principles Diseases Course with 45 s-year students. The consisted 60 type A MCQs. Item (IA) generated KR20, index (DIF), (DIS), distractor (DE)....
Sedentary lifestyles, urbanization and improvements in socio-economic status have had serious effects on the burden of diabetes across world. Diabetes is one 10 leading causes death globally, individuals with a 2-3-fold increased risk all-cause mortality. Adipose tissue increasingly understood as highly active endocrine gland that secretes many biologically substances, including adipocytokines. However, exact discrete pathophysiological links between obesity T2DM are not yet fully...
The ongoing outbreak of SARS-CoV-2 represents a significant challenge to international health. Several reports have highlighted the importance ACE2 on pathogenesis COVID-19. spike protein efficiently binds angiotensin-converting enzyme 2 (ACE2) receptors and facilitates virus entry into host cell. In present study, we hypothesize that functional insertion/deletion polymorphism-rs4646994 I/D rs4240157 T > C in ACE gene could be associated with infection mortality.This study included 117...
Background: Type 2 diabetes mellitus (T2DM) is becoming a major global health concern, especially in developing nations. The high prevalence of obesity and related cases are attributed to rapid economic progress, physical inactivity, the consumption high-calorie foods, changing lifestyles. Objectives: We investigated roles pro-inflammatory chemokines CCL1, 2, 4, 5 T2DM with varying levels Asir region Saudi Arabia. Materials Methods: In total, 170 confirmed subjects normal control group were...
Background Although the coronavirus disease 2019 (COVID-19) pandemic continues to rage worldwide, clinical and laboratory studies of this have been limited in many countries. We investigated epidemiologic, clinical, findings COVID-19 infected patients identify effective indicators correlated with disease. Methods A retrospective study was conducted at King Abdullah Hospital Bisha Province, Saudi Arabia, from March 20 June 30, 2020. Patients different age groups were confirmed as having...
Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by persistent hyperglycemia and associated with serious complications. The risk factors for T2DM include both genetic lifestyle factors. Genome‑wide association studies have indicated the of variations many diseases, including T2DM. Glucokinase (GCK) plays key role in regulation insulin release pancreas catalyzes first step glycolysis liver. Genetic alterations GCK gene been implicated hypoglycemia. MicroRNAs (miRNAs/miRs)...
Student-centered educational strategies like problem-based learning (PBL), case-based (CBL), team-based (TBL), and seminars enhance group self-learning. This study was carried out to evaluate students' achievements in anatomy topics delivered through TBL sessions survey student preferences regarding these two modalities learning.TBL conducted individual readiness assurance tests (IRATs), (GRATs), mini-lectures, application exercises. Seminars included pretests, peer lecturing, posttests. The...
Non-alcoholic steatohepatitis (NASH) is characterized by liver inflammation, fat accumulation, and collagen deposition. Due to the limited availability of effective treatments, there a pressing need develop innovative strategies. Given complex nature disease, employing combination approaches essential. Hedgehog signaling has been recognized as potentially promoting NASH, cholesterol can influence this modifying conformation PTCH1 SMO activity. HSP90 plays role in stability GLI proteins. We...
We aimed to evaluate the awareness and knowledge of osteoporosis in a sample 141 health professionals.A group professionals (medical, surgical, primary care nursing departments) were enrolled this cross-sectional study period from August 2017 November 2017. The participants completed questionnaire composed 19 questions about which covering main domains on osteoporosis. Each correct answer carried 1 point whereas incorrect or 'don't know' 0 points. This gave total score range 0-19. A cut-off...
Background: Rheumatoid arthritis (RA) in Saudi Arabia (SA) is a significant health concern with notable impact on individuals and the healthcare system. This study aimed to investigate prevalence profile of comorbidities patients RA. Methodology: retrospective descriptive involving 150 RA from August 2022 2023, which was conducted at Khamis Mushait General Hospital, major institution SA. We examined medical records gather pertinent information. Stata Statistical Software: Release 18 (2023;...
Sorafenib is a multikinase inhibitor employed for managing hepatocellular carcinoma (HCC). The emergence of sorafenib resistance presents an obstacle to its therapeutic efficacy. One notable approach overcoming the exploration combination therapies. role hedgehog signaling in has been also examined HCC. R51211, known as itraconazole, safely clinical practice. Through vitro and vivo investigations, we assessed potential R51211 enhance efficacy by inhibiting signaling. zero-interaction potency...
Diabetes mellitus constitutes a big challenge to the global health care system due its socioeconomic impacts and very serious complications. The incidence prevalence rate are increased in Gulf region including KSA. Type 2 diabetes (T2DM) is caused by diverse risk factors obesity, unhealthy dietary habits, physical inactivity, smoking genetic factors. molecular studies have helped detection of many single nucleotide polymorphisms (SNP) with different diseases cancers, cardiovascular T2DM....
Hospitalized patients are likely to have chronic illnesses and at an increased risk of mortality due infection caused by MDR bacteria. We aimed identify carbapenem-resistant genes carrying Klebsiella pneumoniae (K. pneumoniae) isolates their factors recovered from adult with comorbidities. A cross-sectional study was carried out between April 2021 December King Abdullah Hospital (KAH) in Bisha province, Saudi Arabia. Seventy-one multi-drug resistant K. clinical samples screened for...
Abstract Background Although the coronavirus disease 2019 (COVID-19) pandemic continues to rage worldwide, clinical and laboratory studies of this have been limited in many countries. We investigated epidemiologic, clinical, findings COVID-19 infected patients identify effective indicators correlated with disease. Methods A retrospective study was conducted at King Abdullah Hospital Bisha Province, Saudi Arabia, from March 20 June 30, 2020. Patients different age groups were confirmed as...
Background: Population-based studies are the gold standard to understand burden of different diseases, plan health care policy and resource allocation, provide an accurate estimate disease several indices including mortality. However, population-based difficult undertake in a resource-limited situation where no robust data bases registries available. Therefore, hospital-based cohorts may be used inform about community health. Objectives: We sought study pattern causing admission, hospital...
Background: There is limited information about the clinical profile and outcome on patients admitted to a coronary care unit (CCU) in Saudi Arabia available.Objective: The aim of this study was evaluate reasons for admission, characteristics, predictors CCU patients.Materials methods: data 392 secondary centre southern region from 1 January 2017 31 December were collected. Data that extracted included demographics, admission diagnosis outcome.Results: A total patients, comprising 305...