- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Retinal Diseases and Treatments
- Ophthalmology and Visual Impairment Studies
- Ocular Surface and Contact Lens
- Wound Healing and Treatments
- Antimicrobial agents and applications
- Proteoglycans and glycosaminoglycans research
- Ergonomics and Musculoskeletal Disorders
- Historical Astronomy and Related Studies
- Nanoplatforms for cancer theranostics
- Retinal Development and Disorders
- Silk-based biomaterials and applications
- Color perception and design
- Electrospun Nanofibers in Biomedical Applications
Weifang Medical University
2021-2022
Aerie Pharmaceuticals (United States)
2020
SUNY College of Optometry
2007
The Ohio State University
2001-2007
New open-angle glaucoma (OAG) and ocular hypertension (OHT) therapies that reduce treatment burden improve outcomes relative to currently available agents are needed. Netarsudil, a novel Rho kinase inhibitor approved by the US Food Drug Administration, reduces intraocular pressure (IOP) increasing trabecular outflow. Two phase 3 superiority studies compared fixed-dose combination (FDC) of netarsudil prostaglandin latanoprost with each active component for IOP-lowering efficacy.Pooled...
Healing of various skin wounds is a lengthy process and often combined with bacterial infection scar formation. Biomimetic electrospun nanofibrous wound dressing loaded materials that possess properties dual antibacterial tissue repair would be developed to address this problem. In study, composite chitosan material containing Cur@β-CD/AgNPs nanoparticles composed silver curcumin possessed synergic effects on activity healing. The functionalized showed effective against both Gram-negative...
Purpose. Axial length is traditionally measured using A-scan ultrasound. The IOLMaster a new instrument that uses partial coherence interferometry to measure axial length. We compared the repeatability of these techniques for both an experienced and inexperienced observer, agreement between two techniques, effect cycloplegia on measurements. Methods. Five measurements three anterior chamber depth were taken with in sessions separated by 1 12 days 20 young adults. examiners each took...
To study the effects of age, race, years contact lens wear, and degree myopia on endothelial cell density, coefficient variation, percentage hexagonal cells.A total 149 subjects with a broad variation in age (19 to 71 years), refractive error (39.6% had over -5.00 D), history (13.4% >20 wear) were examined. Most white, but one third Asian. The Konan specular microscope was used capture images from 1 eye each subject analyzed KSS-300 software. Multiple regression analysis build models...
Precis: In pooled phase III analyses, once-daily netarsudil 0.02% resulted in intraocular pressure (IOP) reduction that was noninferior to twice-daily timolol 0.5%, with minimal treatment-related serious or systemic adverse events (AEs). Ocular AEs were generally tolerable. Purpose: The purpose of this study assess the efficacy and safety Rho kinase inhibitor patients open-angle glaucoma ocular hypertension. Patients Methods: Pooled analysis data from ROCKET-1 4 studies ( PM ) primary...
To describe the changes in endothelial cell density (ECD), coefficient of variation (CV), percentage hexagonal cells (%HEX), and central corneal thickness (CCT) following 3 months therapy with netarsudil 0.02%/latanoprost 0.005% fixed combination, to compare these those seen 0.02% or latanoprost eyes ocular hypertension open-angle glaucoma. A subset subjects enrolled a Phase evaluation intraocular pressure-lowering efficacy safety combination once daily (QD) versus each its individual...
Purpose. We evaluated the ConfoScan3 confocal microscope and its associated software that allows automated analysis of corneal endothelial morphology. Methods. Images were taken on 30 normal subjects 29 contact lens wearers with Konan SP-9000 specular ConfoScan3. The images analyzed KSS-300 (center method). Confoscan3 first method then edited manually (semiautomated agreement between methods was by calculating difference pairs measurements, determining mean standard deviation these...
To describe the changes in endothelial cell density (ECD), coefficient of variation (CV), and percent hexagonal cells (%HEX) after 3 months therapy with netarsudil (Rhopressa; Aerie Pharmaceuticals Inc, Durham, NC) 0.02% dosed once daily (QD) or twice (BID) to compare these those seen timolol 0.5% BID eyes ocular hypertension (OHTN) open-angle glaucoma (OAG).Post hoc analysis data from a phase evaluation intraocular pressure (IOP)-lowering efficacy safety versus 0.5%.A subset study subjects...
Saturday, December 8, 2001. Posters: Academy Information, Cornea and Contact lenses, Ocular Disease, Optics Refraction, Vision Science, Visual Biology: PDF Only
Saturday, December 14, 2002: Posters: Binocular Vision, Pediatric Optometry, Public Health, Vision Science: PDF Only