A5016852244- Cystic Fibrosis Research Advances
- Neonatal Respiratory Health Research
- Pneumonia and Respiratory Infections
- Tracheal and airway disorders
- Glioma Diagnosis and Treatment
- Pediatric health and respiratory diseases
- Neuroblastoma Research and Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Systemic Lupus Erythematosus Research
- Salivary Gland Disorders and Functions
- CAR-T cell therapy research
- Ocular Diseases and Behçet’s Syndrome
- Antibiotic Resistance in Bacteria
- Migraine and Headache Studies
- Cardiovascular Syncope and Autonomic Disorders
- Cancer Treatment and Pharmacology
- Diabetes and associated disorders
- Ultrasound in Clinical Applications
- Orthopedic Infections and Treatments
- Infections and bacterial resistance
- Hematological disorders and diagnostics
- Neurofibromatosis and Schwannoma Cases
- Research on Leishmaniasis Studies
- Ophthalmology and Eye Disorders
- COVID-19 and healthcare impacts
Bambino Gesù Children's Hospital
2022-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2022-2025
Center for Rheumatology
2024
Sapienza University of Rome
2021-2022
Currently, there is a lack of data concerning the organization and characteristics Italian pediatric physiotherapy units for treatment patients with chronic lung diseases, especially those rare conditions such as Primary Ciliary Dyskinesia (PCD) non-Cystic Fibrosis bronchiectasis (NCFB). A national descriptive study based on survey questionnaire was conducted. The consisted three different sections: distribution centres, services provided by respiratory therapists, physiotherapists'...
Multiple Breath washout (MBW) represents an important tool to detect early a possible pulmonary exacerbation especially in Cystic Fibrosis (CF) disease. Lung clearance index (LCI) is the most commonly reported multiple breath and last years was used as management measure for evaluation. Our aim analyze clinical utility of LCI variability CF after intravenous (IV) antibiotic therapy. A single-center study conducted at Unit Bambino Gesù Children's Hospital among hospitalized > 3 patients...
Background: Atraumatic limping is a frequent cause of consultation in Pediatric Emergency Departments (PED) and often represents challenge for pediatricians its variability etiology ranging from benign causes to potential crippling conditions. The aims this research are illustrate the clinical features acute children (LC) identify possible red flags that could help make diagnosis severe pathologies. Methods: We carried out retrospective study about non-traumatic referred PED Bambino Gesù...
Objectives Paediatric Sjögren’s syndrome (pSS) is a rare chronic autoimmune disorder, characterised by inflammation of exocrine glands. B cell hyperactivation plays central role in adult-onset Sjogren. This study was designed to analyse and T phenotype, levels BAFF, selection autoreactive cells patients with pSS. Methods A total 17 diagnosed pSS 13 healthy donors (controls) comparable for age were enrolled the study. subsets frequency peripheral blood analysed flow cytometry. Levels BAFF...
Background: Coronavirus pandemic has influenced our society with social distancing and management of chronic disease such as cystic fibrosis (CF). During the Italian lockdown from March to May 2020, CF patients reduced number outpatient visits, limited interactions spent more time at home. The aim this study is evaluate impact on body mass index (BMI) lung function tests patients. Methods: We retrospectively reviewed clinical data about 111 followed in Regional Cystic Fibrosis Reference...
The use of mobile applications helps improving self-management in adolescents with asthma. However, no evidence is available for children preschool wheezing. In addition, we have data on the reliability medical history collected at visits. first aim was to assess feasibility a smartphone app management wheezing; secondly aimed evaluate anamnestic during face-to-face interviews.
Objective to investigate the trend of autoantibody titers during a 2-year follow-up in pediatric systemic lupus erythematosus (pSLE) and Sjögren's syndrome (pSS). Methods Autoantibodies testing was performed every 3-4 months 2 years from disease onset cohort children with pSLE pSS. Results We enrolled 21 22 All patients at showed ANA significantly lower compared onset. Eleven (73%) were still positive years, while 4 (26%) became negative. At diagnosis, 12 (80%) homogeneous pattern, 3 (20%)...
Down syndrome (DS) is the most common chromosome abnormality with a unique cancer predisposition pattern: higher risk to develop acute leukemia and lower incidence of solid tumors. In particular, brain tumors are rarely reported in DS population, biological behavior natural history not well described identified. We report case 10-year-old child who presented medulloblastoma (MB). Histological examination revealed classic MB focal anaplasia molecular profile showed presence CTNNB1 variant...
Brain tumors are the most common solid neoplasms of childhood. They frequently reported in children with Neurofibromatosis type 1 (NF1). The frequent central nervous system malignancies described NF1 optic pathway gliomas and brainstem gliomas. Medulloblastoma (MB) patients is extremely rare, to our knowledge, only 10 cases without molecular characterization literature date. We report case a 14-year-old girl that came attention for an incidental finding lesion arising from cerebellar vermis....
BACKGROUND: Late-presenting congenital diaphragmatic hernia (L-CDH) diagnosis is a challenge for its clinical various presentation. In literature radiologic misdiagnosis up to 62%. The aim of this study analyze findings about our cases series in particular setting Pediatric Emergency Department (PED) and review literature. METHODS: We retrospectively analyzed the medical records children older than 1 month, operated L-CDH from November 2009 December 2019 presented PED, with total 20 (5...
Abstract Background: Currently, there is a lack of data concerning the organization and characteristics Italian pediatric physiotherapy units for treatment patients with chronic lung diseases, especially those rare conditions such as primary ciliary dyskinesia (PCD) non-Cystic Fibrosis bronchiectasis (NCFB). Methods: A national descriptive study based on survey questionnaire was conducted. The consisted three different sections: distribution centres, services provided by respiratory...
Acinetobacter baumannii is one of the pathogens most involved in health care-associated infections recent decades. Known for its ability to accumulate several antimicrobial resistance mechanisms, it possesses oxacillinase blaoxa-23, a carbapenemase now endemic Italy. species are not frequently observed patients with cystic fibrosis, and multidrug-resistant A. rare event these patients. Non-mucoid carrying blaoxa-23 gene has been sporadically detected. Here, we describe methods used detect...
Abstract Cutaneous leishmaniasis (CL) is the most frequent form of leishmaniasis. The auricle an extremely rare site for CL in Old World. Auricular may be mistaken other entities, such as relapsing polychondritis (RP). Here we report a pediatric case World auricular mimicking RP child successfully treated with intralesional liposomal amphotericin B.