A5053912573- Skin and Cellular Biology Research
- Autoimmune Bullous Skin Diseases
- Vascular Malformations and Hemangiomas
- Dermatological and Skeletal Disorders
- Parvovirus B19 Infection Studies
- Genetic and rare skin diseases.
- Tumors and Oncological Cases
- RNA regulation and disease
- Hair Growth and Disorders
- Vascular Malformations Diagnosis and Treatment
- Wnt/β-catenin signaling in development and cancer
- Nail Diseases and Treatments
- Viral-associated cancers and disorders
- Histiocytic Disorders and Treatments
- Dermatological and COVID-19 studies
- Cell Adhesion Molecules Research
- Immunodeficiency and Autoimmune Disorders
- Vascular Tumors and Angiosarcomas
- Dermatology and Skin Diseases
- Eosinophilic Disorders and Syndromes
- Allergic Rhinitis and Sensitization
- Streptococcal Infections and Treatments
- Cancer and Skin Lesions
- Urticaria and Related Conditions
- Cellular Mechanics and Interactions
Bambino Gesù Children's Hospital
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2015-2024
Istituto Dermopatico dell'Immacolata
2021-2024
Hospital Infantil Universitario Niño Jesús
2022-2023
Fundación Instituto Valenciano de Oncología
2022-2023
Helsinki University Hospital
2022-2023
Aristotle University of Thessaloniki
2022-2023
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2022-2023
Nantes Université
2022-2023
Technical University of Munich
2022-2023
Acral chilblain-like lesions are being increasingly reported during COVID-19 pandemic. However, only few patients proved positivity for SARS-CoV-2 infection. The relationship between this skin manifestation and infection has not been clarified yet.To thoroughly characterize a prospective group of with to investigate the possible infection.Following informed consent, underwent (i) clinical evaluation, (ii) RT-PCR serology testing SARS-CoV-2, (iii) digital videocapillaroscopy finger toe...
These guidelines for the management of congenital ichthyoses have been developed by a multidisciplinary group European experts following systematic review current literature, an expert conference held in Toulouse 2016, and consensus on discussions. summarize evidence expert-based recommendations intend to help clinicians with these rare often complex diseases. comprise two sections. This is part two, covering complications particularities some forms ichthyosis.
The aim of this guidance is to provide recommendations clinicians and other interested parties on chronic urticaria in children. Italian Society for Pediatrics (SIP), the Allergy Immunology (SIAIP), Pediatric dermatology (SIDerP) convened a multidisciplinary panel that prepared clinical guidelines diagnosis management childhood. Key questions epidemiology, natural history, diagnosis, were developed. literature was systematically searched evaluated, rated algorithms treatment focus...
These guidelines for the management of congenital ichthyoses have been developed by a multidisciplinary group European experts following systematic review current literature, an expert conference held in Toulouse 2016 and consensus on discussions. They summarize evidence expert-based recommendations are intended to help clinicians with these rare often complex diseases. comprise two sections. This is part one, covering topical therapies, systemic psychosocial management, communicating...
Sturge-Weber Syndrome (SWS) is a rare, sporadic neurocutaneous disorder affecting the skin, brain, and eyes, due to somatic activating mutations in GNAQ or, less commonly, GNA11 gene. It characterized by at least two of following features: facial capillary malformation, leptomeningeal vascular ocular involvement. The spectrum clinical manifestations includes headache, seizures, stroke-like events, intellectual disability, glaucoma, asymmetry, gingival hyperplasia, etc. An early diagnosis...
Background. Organ transplant recipients are at an increased risk of nonmelanoma skin cancer.Few data concern heart transplantation and populations from southern Europe. Methods. A total 1329 patients who received their first kidney (1062 subjects) or allograft (267 were included in a partly retrospective cohort study to evaluate the cancer. The incidence rate per 1000 person-years cumulative computed. Standardized morbidity ratio was estimated by comparison with Italian cancer registry data....
Families of children affected with atopic dermatitis (AD) often report fear and anxiety regarding treatment topical corticosteroids (TCS), which may lead to reduced compliance. The objective our study was measure, through a standardized questionnaire, TCS in families pediatric patients AD identify items associated fear. were enrolled 9 Italian centers dermatology. Enrolled parents invited fill questionnaire including questions on sociodemographic clinical characteristics 3 sets...
Abstract Objectives Clinical studies have shown low toxicity and a favorable safety profile for sirolimus in vascular anomalies. Here, we describe severe adverse events (SAEs) observed during “off‐label use” Methods We performed retrospective, multicenter chart review SAEs “off‐label” therapy anomalies analyzed these cases by predesigned workflow. Results identified 17 14 patients diagnosed with generalized lymphatic anomaly ( n = 4), Gorham–Stout disease 2), central conducting 1),...
Genetic mutations in the plectin gene (PLEC) cause autosomal recessive forms of epidermolysis bullosa simplex (EBS) associated with either muscular dystrophy (EBS-MD) or pyloric atresia (EBS-PA). Phenotype-genotype analysis has suggested that EBS-MD is due mostly to genetic affecting central rod domain plectin, and EBS-PA outside this domain.This study aimed describe new phenotypes patients EBS-PA, identify novel PLEC establish genotype-phenotype correlations.Seven a suspicion EBS linked...
Objective: VASCERN (https://vascern.eu/) is the European Reference Network for Rare Multisystemic Vascular Diseases. VASCERN-VASCA working group within that focuses on study of vascular anomalies. One objectives this to establish patient pathways guide physicians toward efficient diagnostic and management measures. The pathway presented here focused capillary malformations (CMs). Methods: Nominal Group Technique, a structured variation small discussion was used. Two facilitators were...
Abstract Background Recessive dystrophic epidermolysis bullosa (RDEB) is a rare and severe mucocutaneous fragility disorder due to mutations in the COL7A1 gene encoding collagen VII, major constituent of anchoring fibrils essential for epithelial adhesion. RDEB characterized by unremitting blistering, chronic painful wounds fibrotic scarring that results hand foot pseudosyndactyly, microstomia, esophageal strictures. complications include nutritional compromise, anemia, failure thrive,...
In 2019, a group of experts published the first European guidelines for management congenital ichthyoses after multidisciplinary expert meeting held in 2016. An update these and literature search was planned every 5 years, given clinical, molecular therapeutic advances, including use biologic therapies. We present here updated that have been developed by reorganized international systematic review recent literature, discussions, consensus reached at an conference June 2023. The provide...
In 2019, a group of experts published the first European guidelines for management congenital ichthyoses after multidisciplinary expert meeting held in 2016. An update these and literature search was planned every 5 years, given clinical, molecular therapeutic advances, including use biologic therapies. We present here updated that have been developed by reorganized international systematic review recent literature, discussions, consensus reached at an conference June 2023. The provide...
Abstract Recessive X‐linked ichthyosis (XLI), the second most common ichthyosis, is caused by mutations in STS gene encoding steroid sulfatase enzyme. A complete deletion of found 85%‐90% cases. Rarely, larger deletions involving contiguous genes are detected syndromic patients. We report clinical and molecular genetic findings a series 35 consecutive Italian male All patients underwent testing MLPA or aCGH, followed, case negative results, next‐generation sequencing analysis....