- Medical Imaging Techniques and Applications
- Advanced X-ray and CT Imaging
- Radiopharmaceutical Chemistry and Applications
- Cardiac Imaging and Diagnostics
- Radiomics and Machine Learning in Medical Imaging
- Bone fractures and treatments
- Anesthesia and Neurotoxicity Research
- Receptor Mechanisms and Signaling
- Advanced MRI Techniques and Applications
- Phosphodiesterase function and regulation
- Cardiovascular Disease and Adiposity
- Neuroscience of respiration and sleep
- Trauma Management and Diagnosis
- Cardiac Arrest and Resuscitation
- Cardiac Structural Anomalies and Repair
- Inflammatory mediators and NSAID effects
- Head and Neck Cancer Studies
- Coronary Interventions and Diagnostics
- Cancer, Stress, Anesthesia, and Immune Response
- Hepatocellular Carcinoma Treatment and Prognosis
- Functional Brain Connectivity Studies
- Mycobacterium research and diagnosis
- Microtubule and mitosis dynamics
- Neuroscience and Neuropharmacology Research
- Mechanical Circulatory Support Devices
Yeouido St. Mary's Hospital
2024
Catholic University of Korea
2016-2024
Dongguk University
2023
University of Manitoba
2023
Columbia University Irving Medical Center
2018-2022
Kyung Hee University Medical Center
2021
Johns Hopkins University
2011-2021
Gachon University Gil Medical Center
1999-2019
University of Maryland, Baltimore
2014-2018
New York Hospital Queens
2018
Detection of colorectal polyps through colonoscopy is an essential practice in prevention cancers. However, the method itself labor intensive and subject to human error. With advent deep learning-based methodologies, specifically convolutional neural networks, opportunity improve upon prognosis potential patients suffering with cancer has appeared automated detection segmentation polyps. Polyp a number problems such as model overfitting generalization, poor definition boundary pixels, well...
BACKGROUNDThis study was undertaken to determine what characteristics should be recorded on which days build a predictive model for selection of Day 3 embryos.
Identification of safe and valid PET radioligands for metabotropic glutamate receptor, type 5 (mGluR5), is essential to measure changes in brain mGluR5 neuropsychiatric disorders, confirm central occupancy drug candidates, guide dose selection obtaining an optimum therapeutic window. Here we present the results a first-in-human study assessing safety effectiveness novel radiopharmaceutical, <sup>18</sup>F-3-fluoro-5-[(pyridin-3-yl)ethynyl]benzonitrile (<sup>18</sup>F-FPEB), quantifying...
The physical role of nanometre-sized metal particles (Ag, Zr, Cu) in the generation discharge plasma over surface zeolites is presented. optical observation system, consisting a microscope–ICCD camera, was applied to observe on supported nanoparticle. zeolite nanoparticles assisted expand wide area. Among tested active metals this study, silver exhibited most prominent influence plasmas zeolites. On other hand, limited edges when bare were used. difference shape and area also found be...
In the mouse, osteoblast-derived hormone Lipocalin-2 (LCN2) suppresses food intake and acts as a satiety signal. We show here that meal challenges increase serum LCN2 levels in persons with normal or overweight, but not individuals obesity. Postprandial correlate inversely hunger sensation challenged subjects. further through brain PET scans of monkeys injected radiolabeled recombinant human (rh-LCN2) autoradiography baboon, macaque, sections, crosses blood-brain barrier localizes to...
We evaluated (−)-2-(6-[<sup>18</sup>F]fluoro-2,3′-bipyridin-5′-yl)-7-methyl-7-aza-bicyclo[2.2.1]heptane (<sup>18</sup>F-AZAN), a novel radiotracer that binds to α4β2 nicotinic acetylcholine receptors (α4β2-nAChRs) and shows high specific binding rapid reversible kinetics in the baboon human brain. <b>Methods:</b> tested safety tolerability test–retest reliability (<i>n</i> = 5) proposed initial quantification of <sup>18</sup>F-AZAN 3 healthy subjects who had nicotine exposure 9 did not. also...
We have developed a small scintillation camera dedicated to breast imaging and evaluated the performance of system. In order increase limited field view (FOV) determined by size position-sensitive photomultiplier tube (PSPMT), characteristics diverging hole collimator (DHC) were also investigated. The system consists an NaI(Tl) crystal (60 mm x 60 6 mm) coupled Hamamatsu R3941 PSPMT, resistor chain circuit, preamplifiers, nuclear instrument modules, analogue digital converter PC for control...
Abstract Background Positron emission tomography (PET)‐based measures of baseline total‐body tumor burden may improve risk stratification in intermediate‐risk Hodgkin lymphoma (HL). Materials and methods Evaluable patients were identified from a cohort treated homogeneously with the same combined modality regimen on Children's Oncology Group AHOD0031 study. Eligible had high‐quality PET scans. Metabolic volume (MTV) total lesion glycolysis (TLG) each measured based 15 thresholds for every...
Objectives/Hypothesis To compare the diagnostic efficacy of positron emission tomography (PET) with F‐18 fluorodeoxyglucose (FDG‐PET)/computed (CT) to that contrast‐enhanced high‐resolution CT (HRCT) and assess value a combinatorial approach in detection recurrent squamous cell cancer head neck (HNC) FDG‐PET/CT without HRCT comparison standard‐of‐care follow‐up—physical examination (PE) endoscopy (E)—in determination locally HNC. Study Design Retrospective study. Methods A total 103 patients...
In this study, we aimed to evaluate whether nonalcoholic fatty liver disease (NAFLD) was associated with the presence and morphology of coronary atherosclerotic plaques shown by multidetector computed tomography (MDCT) in asymptomatic subjects without a history cardiovascular disease.We retrospectively enrolled 772 consecutive South Korean individuals who had undergone both dualsource 64-slice MDCT angiography hepatic ultrasonography during general routine health evaluations. The studies...
Corneal dystrophy typically refers to a group of rare hereditary disorders with heterogeneous genetic background. A comprehensive molecular analysis was performed characterize the spectrum corneal dystrophies in Korean patients. Patients various underwent thorough ophthalmic examination, histopathologic and Sanger sequencing. total 120 probands were included, mean age 50 years (SD = 18 years) 70% female. 26 mutations five genes (14 clearly pathogenic 12 likely pathogenic) identified 49...
Two patients who presented with ophthalmoplegic migraine underwent electroencephalography, brain magnetic resonance imaging, cerebral angiography, and technetium Tc 99m ethyl cysteinate dimer single photon emission computed tomography (SPECT) during an attack. Follow-up SPECT was performed after neurologic symptoms resolved. In both patients, attack of ophthalmoplegia headache demonstrated significantly decreased regional blood flow (rCBF) in the thalamus on side ophthalmoplegia; rCBF...
The strength and nature of the relationship between myocardial perfusion imaging (MPI), coronary flow reserve (CFR), artery calcium (CAC) thoracic aorta (TAC) remain to be clarified.
<b><i>Purpose:</i></b> This study aimed to evaluate the relationship between macular structural changes and visual prognosis after pars plana vitrectomy (PPV) for proliferative diabetic retinopathy. <b><i>Methods:</i></b> The included 60 eyes that had undergone PPV. Macular optical coherence tomography (OCT) findings were classified into 5 groups preoperatively 10 postoperatively. Best-corrected acuity (BCVA) analyzed according pre-...
Journal Article Prodomain Processing of Recombinant Plasmepsin II and IV, the Aspartic Proteases Plasmodium falciparum, Is Auto- Trans-Catalytic Get access Yong Man Kim, Kim ‡To whom correspondence should be addressed. Tel: +82-63-850-6769, Fax: +82-63-857-0342, E-mail: hyunpk@wonkwang.ac.kr Search for other works by this author on: Oxford Academic PubMed Google Scholar Mi Hyang Lee, Lee Tae Gwang Piao, Piao John Wha Jong Ho SungGa Kyung Min Choi, Choi Jing Hua Jiang, Jiang Ue Hyun Park The...
FDG PET/CT, an established imaging modality for staging and restaging workup of malignancies, also demonstrates increased uptake in infectious or inflammatory conditions, including both noninfectious granulomatous processes. A 65-year-old man with a history hepatocellular carcinoma status post-wedge resection chemoembolization the primary tumor referred evaluation extrahepatic metastases determining surgical eligibility liver transplantation. The patient underwent PET/CT associated...
A 22-year-old woman with Hodgkin lymphoma underwent a staging 18F-FDG PET/CT scan, which showed an intense uptake in the right proximal femur, addition to FDG-avid mediastinal and cervical lymph nodes. The patient thus was diagnosed stage IV bone marrow involvement. Postchemotherapy restaging scan complete resolution of nodal but persistent activity femur. Radiography biopsy confirmed liposclerosing myxofibrous tumor.