Sara Marchetti

ORCID: 0000-0002-8767-9962
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About
Contact & Profiles
Research Areas
  • Air Quality and Health Impacts
  • Energy and Environment Impacts
  • Extracellular vesicles in disease
  • Climate Change and Health Impacts
  • COVID-19 impact on air quality
  • Vehicle emissions and performance
  • Atmospheric chemistry and aerosols
  • Toxic Organic Pollutants Impact
  • Thermochemical Biomass Conversion Processes
  • Air Quality Monitoring and Forecasting
  • Energy, Environment, and Transportation Policies
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Noise Effects and Management
  • Fire dynamics and safety research
  • Mesenchymal stem cell research
  • Reading and Literacy Development
  • Hydrogen Storage and Materials
  • Stress Responses and Cortisol
  • MicroRNA in disease regulation
  • Diabetic Foot Ulcer Assessment and Management
  • Peripheral Artery Disease Management
  • Fuel Cells and Related Materials
  • Fire effects on ecosystems
  • Immune cells in cancer
  • Reconstructive Surgery and Microvascular Techniques

University of Milano-Bicocca
2016-2024

Humanitas University
2019-2020

Istituti di Ricovero e Cura a Carattere Scientifico
2019-2020

University of Bologna
2013

Hi-Z Technology (United States)
2005

Mario Negri Institute for Pharmacological Research
1992

Bone marrow Mesenchymal Stem Cells (BM-MSCs), due to their strong protective and anti-inflammatory abilities, have been widely investigated in the context of several diseases for possible therapeutic role, based on release a highly proactive secretome composed soluble factors Extracellular Vesicles (EVs). BM-MSC-EVs, particular, convey many beneficial features parental cells, including direct indirect β-amyloid degrading-activities, immunoregulatory neurotrophic abilities. Therefore, EVs...

10.3390/cells8091059 article EN cc-by Cells 2019-09-10

The mechanism by which glucocorticoids induce various cellular responses in different tissues is only partially understood. Here we demonstrate that stabilize the actin cytoskeleton of several cell types, as revealed increased resistance filaments to disrupting effect cytochalasin and visible thickening filament bundles. These effects require hours develop, protein synthesis, are accompanied expression actin-binding caldesmon. data may help explain why inhibit corticotropin release from...

10.1073/pnas.89.9.3775 article EN Proceedings of the National Academy of Sciences 1992-05-01

Biomass burning (BB) represents a global concern due to its impact on air pollution, health and climate change, resulting in 2.3 million premature deaths yearly. BB the residential sector is one of main sources primary Particulate Matter emissions. emits significant amount black brown carbon, Polycyclic Aromatic Hydrocarbons, contributes secondary formation ozone by photochemical reaction volatile organic compounds nitrogen oxides. On other side, green renewable alternative source fossil...

10.5194/egusphere-egu25-11081 preprint EN 2025-03-14

COVID-19 pandemic had a significant impact on global public health. The spread of the disease was related to high transmissibility SARS-CoV-2 virus but incidence and mortality rate suggested possible relationship with environmental factors. Air pollution has been hypothesized play role in transmission resulting severity disease. Here we report plausible vitro toxicological mode action by which fine particulate matter (PM2.5) could promote higher infection PM2.5 promotes 1.5 fold...

10.1016/j.envint.2023.108131 article EN cc-by-nc-nd Environment International 2023-08-11

Summary This study aims to critically evaluate the effect of photochemical smog on COPD patients in Nigeria. A cohort was recruited from two large hospitals Abuja Symptom questionnaires, daily diaries, dyspnoea scale and measurement lung function were used obtain health data. Real-time air pollution data obtained a monitoring site at airport. Measured concentrations, for precursors smog, are far higher than those recorded developed world where link between respiratory has been observed....

10.18745/pb.19829 article EN 2018-01-16

Greater Cairo (Egypt) is a megalopolis where the studies of air pollution events are extremely high relevance, for geographical-climatological aspects, anthropogenic emissions and health impact. While preliminary on particulate matter (PM) chemical composition in have been performed, no data yet available PM's toxicity. In this work, vitro toxicity fine PM (PM2.5) sampled an urban area during 2017-2018 was studied. The PM2.5 samples collected spring, summer, autumn winter were characterized...

10.3390/ijms20204970 article EN International Journal of Molecular Sciences 2019-10-09

Airborne pathogens represent a topic of scientific relevance, especially considering the recent COVID-19 pandemic. Air pollution, and particulate matter (PM) in particular, has been proposed as possible risk factor for onset spread pathogen-driven respiratory diseases. Regarding SARS-CoV-2 infection, exposure to fine PM (PM2.5, particles with an aerodynamic diameter < 2.5 μm) associated increased incidence disease. To provide useful insights into mechanisms through which might be involved we...

10.1016/j.scitotenv.2024.175979 article EN cc-by The Science of The Total Environment 2024-09-02

Purpose: The aim of this study is to compare the Wechsler Intelligence Scale for Children ® – fourth edition IV (WISC IV) intellectual profile two groups children with specific learning disorder, a group bilingual and monolingual Italian children, in order identify possible significant differences between them. Patients methods: A 48 were included study. preliminary comparison showed homogeneity regarding disorder typology sociodemographic characteristics (age at WISC assessment, sex years...

10.2147/ndt.s121536 article EN cc-by-nc Neuropsychiatric Disease and Treatment 2016-12-01

Abstract Combustion-derived particles (CDPs), due to the presence in their composition of several toxic and carcinogenic chemical compounds, such as polycyclic aromatic hydrocarbons (PAHs) metals, are linked respiratory diseases, including lung cancer. Epithelial-to-mesenchymal transition (EMT) is a crucial step cancer progression, involving morphological phenotypical changes. The study aims investigate how exposure CDPs from different biomass sources might be involved development, focusing...

10.1007/s00204-021-02983-8 article EN cc-by Archives of Toxicology 2021-01-22
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