A5036827222- Gut microbiota and health
- Animal Nutrition and Physiology
- Autophagy in Disease and Therapy
- Clostridium difficile and Clostridium perfringens research
- Probiotics and Fermented Foods
- Adipose Tissue and Metabolism
- Agriculture, Soil, Plant Science
- Pediatric health and respiratory diseases
- Sirtuins and Resveratrol in Medicine
- Toxoplasma gondii Research Studies
- Endoplasmic Reticulum Stress and Disease
- Aquaculture disease management and microbiota
- Ecology and Conservation Studies
- FOXO transcription factor regulation
- Antimicrobial Peptides and Activities
- Photosynthetic Processes and Mechanisms
- Rabbits: Nutrition, Reproduction, Health
- Environmental and Agricultural Sciences
- Healthcare and Venom Research
- Phytoestrogen effects and research
- Humic Substances and Bio-Organic Studies
- Light effects on plants
- Analysis of environmental and stochastic processes
- Adipokines, Inflammation, and Metabolic Diseases
- Lipid metabolism and biosynthesis
Zhejiang University
2020-2022
Institute of Animal Sciences
2020-2021
Ministry of Agriculture and Rural Affairs
2020-2021
Weifang University
2020
University Research Co (United States)
2020
Virginia Tech
2015-2016
Army Medical University
2016
With the ever-growing strict prohibitions on antibiotic growth promoters (AGP) in animal production, in-feed probiotics are becoming attractive alternatives to antibiotics poultry industry. To investigate effects of Paenibacillus polymyxa 10 and Lactobacillus plantarum 16 performance intestinal health broilers, 540 male Cobb 500 broilers 1 d old were randomly divided into 3 groups with 6 replicates per group 30 chicks replicate. Broilers fed either a basal diet or diets supplemented × 108...
Abstract As the pandemic of obesity is growing, a variety animal models have been generated to study mechanisms underlying increased adiposity and development metabolic disorders. Tamoxifen (Tam) widely used activate Cre recombinase that spatiotemporally controls target gene expression regulates in laboratory animals. However, critical question remains as whether Tam itself affects possibly confounds functional genes adipose tissue. Here we administered Cre-absent forkhead box O1 (FoxO1)...
Obesity and related metabolic disorders constitute one of the most pressing heath concerns worldwide. Increased adiposity is linked to autophagy upregulation in adipose tissues. However, it unknown how upregulated contributes aberrant adiposity. Here we show a FoxO1-autophagy-FSP27 axis that regulates adipogenesis lipid droplet (LD) growth adipocytes. Adipocyte differentiation was associated with fat specific protein 27 (FSP27), key regulator adipocyte maturation expansion by promoting LD...
At present, the widespread use of high-dose zinc oxide and antibiotics to prevent post-weaning diarrhea (PWD) in piglets has caused serious environmental problems. To solve this problem, we studied effect HNa as a substitute for (ZnO) on growth performance, immune status, antioxidant capacity piglets. Seventy-two weaned (body weight = 7.42 ± 0.85 kg, 26-d-old) were distributed randomized 2 × 3 factorial design (two sexes three treatments) with six replicates four each. The treatments control...
This study aimed to compare the effects of BaSC06 and antibiotics on growth, digestive functions, antioxidant capacity, macrophage polarization intestinal microbiota pigs for fattening. A total 117 fattening with similar weight genetic basis were divided into 3 groups: Anti group (containing 40g/t Kitasamycin in diet), Anti+Ba 20g/t 0.5×108 CFU/kg diet) Ba 1 108 cfu/Kg diet without any antibiotics). Each treatment was performed three replicates 13 per replicate. Results showed that...
Autophagy is a conserved proteolytic mechanism, which degrades and recycles damaged organs proteins in cells to resist external stress. Probiotics could induce autophagy; however, its underlying molecular mechanisms remain elusive. Our previous study has found that BaSC06 alleviate oxidative stress by inducing autophagy rats. This research aimed verify whether Bacillus amyloliquefaciens SC06 can IPEC-J2 cells, as well explore mechanisms. were first pretreated with 108 CFU/mL BaSC06, then...
This study aimed to investigate whether the combination of Macleaya cordata extract (MCE) and Bacillus could improve laying performance health hens better.
Macrophages are professional phagocytic cells that play a critical role in initiating immune responses by presenting antigen and clearance. The macrophages can be targeted for immunomodulation beneficial microbes, such as probiotics. aim of this study is to investigate the protective effect Saccharomyces boulardii against Clostridium perfringens infection avian macrophage cell line HD11. In study, HD11 were prestimulated with S. 6 h then infected C. 3 h. Results showed enhanced phagocytosis...
Dibutyl phthalate (DBP) is a widely used plasticizer that has been shown to induce germ cell apoptosis-related testicular atrophy and cause reproductive toxicity. Our previous results indicated endoplasmic reticulum (ER) stress-activated autophagy served as self-defense mechanism against DBP-induced apoptosis. However, the specific pathways link ER stress remain unclear. Here, we showed exposure DBP enhanced autophagic flux in mouse spermatocyte-derived GC-2 cells eukaryotic translation...
Clostridium perfringens (C. perfringens) causes intestinal injury through overgrowth and the secretion of multiple toxins, leading to diarrhea necrotic enteritis in animals, including pigs, chickens, sheep. This study aimed investigate protective effects Lactobacillus plantarum (L. plantarum) Lac16 on C. infection-associated porcine epithelial cell line (IPEC-J2). The results showed that L. significantly inhibited growth perfringens, which was accompanied by a decrease pH levels. In...
Abstract Background: The previous study in our team found that supplementation of probiotic Bacillus amyloliquefaciens SC06 (BaSC06) as an alternative to antibiotics (Kitasamycin) can effectively reduce the diarrhea rate and promote growth performance weaned piglets. We speculate BaSC06 may become a better substitute for fattening pigs. Hence, objective present is evaluate effects on performance, digestive functions, antioxidant capacity, macrophage polarization intestinal microbiota...
Abstract Background: Clostridium perfringens causes intestinal injury through overgrowth and secretion of multiple toxins, leading to diarrhea necrotic enteritis in animals, such as pigs. Lactobacillus plantarum ( L. ) Lac16 has been reported protect broilers against C. infection. This study aimed at investigating the protective effects on infection-associated porcine epithelial cell line (IPEC-J2). Results: The results showed that significantly inhibit growth biofilm formation P <...
1. Amadori M., Zanotti C., 2016. Immunoprophylaxis in intensive farming systems: the way forward. Vet. Immunol. Immunopathol. 181, 2−9, https://doi.org/10.1016/j.veti.... CrossRef Google Scholar