A5101625934- Vehicle emissions and performance
- Gut microbiota and health
- Electric Vehicles and Infrastructure
- Animal Nutrition and Physiology
- Probiotics and Fermented Foods
- Air Quality and Health Impacts
- Energy, Environment, and Transportation Policies
- Indoor Air Quality and Microbial Exposure
- Pharmacological Effects of Natural Compounds
- Mesenchymal stem cell research
- Concrete Corrosion and Durability
- Aquaculture disease management and microbiota
- MicroRNA in disease regulation
- Autophagy in Disease and Therapy
- Endoplasmic Reticulum Stress and Disease
- Vehicle Dynamics and Control Systems
- Epigenetics and DNA Methylation
- Smart Materials for Construction
- Corrosion Behavior and Inhibition
- Rabbits: Nutrition, Reproduction, Health
- Biofuel production and bioconversion
- Body Contouring and Surgery
- Atmospheric and Environmental Gas Dynamics
- Antimicrobial Peptides and Activities
- Hippo pathway signaling and YAP/TAZ
People's Hospital of Cangzhou
2025
Nanfang Hospital
2024-2025
Southern Medical University
2024-2025
Integrated Chinese Medicine (China)
2025
Institute of Animal Sciences
2021-2024
Zhejiang University
2021-2024
Qilu University of Technology
2021-2024
Shandong Academy of Sciences
2021-2024
Jinan University
2021-2024
China Automotive Technology and Research Center
2017-2024
Summary Chronic inflammation of adipose tissue is a prominent characteristic many metabolic diseases. Lipid metabolism in consistently dysregulated during inflammation, which characterized by substantial infiltration proinflammatory cells and high cytokine concentrations. Adipose caused variety endogenous factors, such as mitochondrial dysfunction, reactive oxygen species (ROS) production, endoplasmic reticulum (ER) stress, cellular senescence, ceramides biosynthesis mediators...
Bacillus amyloliquefaciens is a well-accepted probiotic, with many benefits for both humans and animals. The ability of intestinal stem cells (ISCs) to develop into several epithelial cell types helps accelerate regeneration. Limited knowledge exists on how bacteria regulated ISCs proliferation Our study investigated the effects supplementation ISC regeneration mucosal barrier functions in piglets exposed lipopolysaccharide (LPS). Eighteen (male, 21 days old) were randomly split 3 clusters:...
Sortilin acts as a key receptor for lipids, growth factors, cytokines, and enzymes participates in pathological cargo loading transferring of extracellular vesicles. Emerging evidence suggests significant role sortilin hyperlipidemia the risk atherosclerosis. Recent epidemiological demonstrated that has been implicated atherosclerosis plaque progression patients with coronary or peripheral artery disease. The present study presents comprehensive review contribution to progression. Here,...
Autophagy is a conserved proteolytic mechanism, which degrades and recycles damaged organs proteins in cells to resist external stress. Probiotics could induce autophagy; however, its underlying molecular mechanisms remain elusive. Our previous study has found that BaSC06 alleviate oxidative stress by inducing autophagy rats. This research aimed verify whether Bacillus amyloliquefaciens SC06 can IPEC-J2 cells, as well explore mechanisms. were first pretreated with 108 CFU/mL BaSC06, then...
As emerging markets, the Belt and Road Initiative (BRI) participating countries have great development room for automobile industries. Yet greater climate change pressure may hinder of upstream downstream industries chain domestic Therefore, a sound carbon emission standard system should be established to guide accounting, emissions management so on. This study selects Singapore, Indonesia, Poland, South Africa, Pakistan as typical research objects, thereby analyzes status standards in BRI...
Abstract Background Pre-eclampsia (PE) is one of the leading causes maternal and fetal morbidity/mortality during pregnancy, alpha-2-macroglobulin (A2M) associated with inflammatory signaling; however, pathophysiological mechanism by which A2M involved in PE development not yet understood. Methods Human placenta samples, serum, corresponding clinical data participants were collected to study pathophysiologic underlying PE. Pregnant Sprague–Dawley rats intravenously injected an adenovirus...
Pet cats frequently have diarrhea in their daily life. Bacillus has a protective role that crucial beneficial functions on intestinal homeostasis. The aim of this research was to investigate the effects compound prevention diarrhea, microbiota and metabolism pet cats. A total 20 (1-2 years old, 3.91 ± 0.92 kg) were randomly divided into two groups fed with basal diet (Control group), or supplemented 3 × 109 CFU/kg (Probiotics group). experiment lasted 33 days.Results showed significantly...
Clostridium perfringens is an important zoonotic pathogen associated with food contamination and poisoning, gas gangrene, necrotizing enterocolitis or necrotic enteritis in humans animals. Dysbacteriosis supposedly the development of C. infection induced enteritis, but detailed relationship between intestinal health, microbiome, infection-induced remains poorly understood. This research investigated effect probiotics on growth performance health broilers, involved roles microbiota microbial...
This study aimed to investigate whether the combination of Macleaya cordata extract (MCE) and Bacillus could improve laying performance health hens better.
Reversine, or 2-(4-morpholinoanilino)-6-cyclohexylaminopurine, is a 2,6-disubstituted purine derivative. This small molecule shows anti-tumor potential by playing central role in the inhibition of several kinases related to cell cycle regulation and cytokinesis. In this study, systematic review demonstrated feasibility pharmacological mechanism effect reversine. Firstly, we grafted MNNG/HOS, U-2 OS, MG-63 osteosarcoma aggregates onto chicken embryonic chorioallantoic membrane (CAM) examine...
This study aims to explore the effects of modified montmorillonite (MMT, copper loading) on growth performance, gut microbiota, intestinal barrier, antioxidative capacity and immune function broilers. Yellow-feathered broilers were randomly divided into control (CTR), (MMT), antibiotic (ANTI) groups. Results revealed that MMT supplementation increased BW ADG decreased F/R during 63-day experiment period. 16S rRNA sequencing showed modulated cecal microbiota composition by increasing relative...
He-Zhao deficiency has been recently characterized with a distinct form of agenesis permanent teeth that is different from other previously reported disorders tooth agenesis. This inherited abnormality suggests some gene(s) associated the development may mutate. In this study, we map gene locus to chromosome 10q11.2. The DNA pooling method combined two-point and multi-point linkage analysis successfully applied. maximum LOD (Zmax) scores for analyses are 13.29 (on marker D10S196) at...
Large-scale use of antimicrobials in agriculture and medicine contributes to antibiotic residues raw foods, the spread antimicrobial resistance (AMR) drug pollution, which seriously threatens human health imposes significant economic burdens on society, suggesting need for novel therapeutic options that prevent or control zoonoses. In this study, four probiotics were selected assess their capability alleviate pathogen-induced damage. Results showed a simulated gastrointestinal juice bile...
The horizontal basal cells (HBCs) of olfactory epithelium (OE) serve as reservoirs for stem during OE regeneration, through proliferation and differentiation, which is important in recovery function. However, the molecular mechanism regulation HBC differentiation after injury remains unclear. Here, we found that yes-associated protein (YAP) was upregulated activated HBCs injury. Deletion YAP led to impairment regeneration functional olfaction Mechanically, by S1P/S1PR2 signaling, thereby...
Abstract Ferulic acid (FA) and p -coumaric ( -CA) are hydroxycinnamic inhibitors that mainly produced during the pretreatment of lignocellulose. To date, inhibitory mechanism compounds on Saccharomyces cerevisiae has not been fully elucidated. In this study, liquid chromatography-mass spectrometry (LC–MS) scanning electron microscopy (SEM) were used to investigate changes in S. cells treated with FA -CA. experiment, control group was denoted as CK, FA-treated F, -CA-treated P. One hundred...
Although it is known that prenatal maternal stress (PNMS) has a negative influence on nervous system development in offspring, there no conclusive evidence clarifying its impact early neurogenesis during development. In this study, we established chick embryo model to investigate how PNMS affects by mimicking an intrauterine environment with elevated dexamethasone levels. The results showed dexamethasone-mimicked significantly suppressed the of gastrula embryos and increased risks neural...
Background: Maintaining lipid metabolic homeostasis is essential for cells to respond environmental stresses, ensure survival, and preserve functionality. Lipophagy, a form of autophagy in which intracellular lysosomes target degrade droplets. The authors hypothesize that pharmacologically enhancing or disrupting lipophagy could either improve impair the retention rates fat grafts. Methods: Human graft nodules, retained six months, were collected through surgical procedures analysis....