A5101662186- Gut microbiota and health
- Probiotics and Fermented Foods
- Semiconductor Lasers and Optical Devices
- Animal Nutrition and Physiology
- Photonic and Optical Devices
- Clostridium difficile and Clostridium perfringens research
- Antimicrobial Peptides and Activities
- 3D IC and TSV technologies
- Semiconductor Quantum Structures and Devices
- Aquaculture disease management and microbiota
- Toxoplasma gondii Research Studies
- Pharmacological Effects of Natural Compounds
- Endoplasmic Reticulum Stress and Disease
- Moringa oleifera research and applications
- Molecular Junctions and Nanostructures
- Liver Disease Diagnosis and Treatment
- Immune Response and Inflammation
- Rabbits: Nutrition, Reproduction, Health
- Pediatric health and respiratory diseases
- Trace Elements in Health
- Advanced Semiconductor Detectors and Materials
- Escherichia coli research studies
- Advanced Optical Sensing Technologies
- Inflammasome and immune disorders
- Phytoestrogen effects and research
Zhejiang University
2007-2025
Hangzhou Medical College
2025
Zhejiang Provincial People's Hospital
2025
Aviation Industry Corporation of China (China)
2024
Beijing Technology and Business University
2024
University of Electronic Science and Technology of China
2024
Institute of Animal Sciences
2020-2023
Chinese Academy of Agricultural Sciences
2022
Guangdong Academy of Agricultural Sciences
2022
Ministry of Agriculture and Rural Affairs
2020-2021
With the ever-growing strict prohibitions on antibiotic growth promoters (AGP) in animal production, in-feed probiotics are becoming attractive alternatives to antibiotics poultry industry. To investigate effects of Paenibacillus polymyxa 10 and Lactobacillus plantarum 16 performance intestinal health broilers, 540 male Cobb 500 broilers 1 d old were randomly divided into 3 groups with 6 replicates per group 30 chicks replicate. Broilers fed either a basal diet or diets supplemented × 108...
Emerging evidence suggests a key role of gut microbiota in maintaining liver functions through modulating the gut-liver axis. In this study, we investigated whether alteration mediated by probiotic Bacillus was involved alleviating oxidative stress- induced injury. Sprague-Dawley rats were orally administered SC06 or SC08 for 24-day period and thereafter intraperitoneally injected diquat (DQ) to induce stress. Results showed that Bacillus, particularly significantly inhibited hepatic...
Bacillus amyloliquefaciens is a well-accepted probiotic, with many benefits for both humans and animals. The ability of intestinal stem cells (ISCs) to develop into several epithelial cell types helps accelerate regeneration. Limited knowledge exists on how bacteria regulated ISCs proliferation Our study investigated the effects supplementation ISC regeneration mucosal barrier functions in piglets exposed lipopolysaccharide (LPS). Eighteen (male, 21 days old) were randomly split 3 clusters:...
At present, the widespread use of high-dose zinc oxide and antibiotics to prevent post-weaning diarrhea (PWD) in piglets has caused serious environmental problems. To solve this problem, we studied effect HNa as a substitute for (ZnO) on growth performance, immune status, antioxidant capacity piglets. Seventy-two weaned (body weight = 7.42 ± 0.85 kg, 26-d-old) were distributed randomized 2 × 3 factorial design (two sexes three treatments) with six replicates four each. The treatments control...
This study aimed to compare the effects of BaSC06 and antibiotics on growth, digestive functions, antioxidant capacity, macrophage polarization intestinal microbiota pigs for fattening. A total 117 fattening with similar weight genetic basis were divided into 3 groups: Anti group (containing 40g/t Kitasamycin in diet), Anti+Ba 20g/t 0.5×108 CFU/kg diet) Ba 1 108 cfu/Kg diet without any antibiotics). Each treatment was performed three replicates 13 per replicate. Results showed that...
This study aimed to investigate the protective effects of Lactobacillus plantarum 16 (Lac16) and Paenibacillus polymyx a 10 (BSC10) against Clostridium perfringens (Cp) infection in broilers. A total 720 one-day-old chicks were randomly divided into four groups. The control Cp group only fed basal diet, while two treatment groups received diets supplemented with Lac16 (1 × 8 cfu·kg −1 ) BSC10 for 21 days, respectively. On day 1 days 14 20, birds except those challenged cfu C. type strain...
Autophagy is a conserved proteolytic mechanism, which degrades and recycles damaged organs proteins in cells to resist external stress. Probiotics could induce autophagy; however, its underlying molecular mechanisms remain elusive. Our previous study has found that BaSC06 alleviate oxidative stress by inducing autophagy rats. This research aimed verify whether Bacillus amyloliquefaciens SC06 can IPEC-J2 cells, as well explore mechanisms. were first pretreated with 108 CFU/mL BaSC06, then...
Pet cats frequently have diarrhea in their daily life. Bacillus has a protective role that crucial beneficial functions on intestinal homeostasis. The aim of this research was to investigate the effects compound prevention diarrhea, microbiota and metabolism pet cats. A total 20 (1-2 years old, 3.91 ± 0.92 kg) were randomly divided into two groups fed with basal diet (Control group), or supplemented 3 × 109 CFU/kg (Probiotics group). experiment lasted 33 days.Results showed significantly...
The aim of this study was to evaluate the dietary effects Bacillus amyloliquefaciens SC06 (SC06) instead antibiotics on growth performance, intestinal health, and microbiota broilers. A total 360 30-day-old Lingnan yellow broilers were randomly allocated into two groups with six replicates per group (30 birds replicate). fed either a non-supplemented diet or supplemented 10 8 colony-forming units lyophilized kilogram feed for 30 days. Results showed that supplementation had no effect...
Clostridium perfringens is an important zoonotic pathogen associated with food contamination and poisoning, gas gangrene, necrotizing enterocolitis or necrotic enteritis in humans animals. Dysbacteriosis supposedly the development of C. infection induced enteritis, but detailed relationship between intestinal health, microbiome, infection-induced remains poorly understood. This research investigated effect probiotics on growth performance health broilers, involved roles microbiota microbial...
Dietary interventions with probiotics have been widely reported to be effective in regulating obesity, and the intestinal microbiota is considered an important environmental factor. However, few reports focus on interactions of microbiota-metabolites-phenotypic variables ob/ob mice, they not characterized great detail. In this study, we investigated effects Bacillus amyloliquefaciens SC06 bile acid metabolism mice using biochemical testing, histochemical staining, high-throughput sequencing...
This study aimed to investigate whether the combination of Macleaya cordata extract (MCE) and Bacillus could improve laying performance health hens better.
The maternal effect of different Se source in offspring young broiler breeders has been reported, but the lasting sources on received limited attention, so this study was conducted to investigate effects retention, antioxidant status, and meat quality 56-d-old breeders. A total two hundred forty 39-wk-old Lingnan Yellow were randomly distributed into 2 treatments, each which replicated 3 times with 40 birds per replicate, a 14-d pretreatment 56-d trial period. treatments fed basal...
Macrophages are professional phagocytic cells that play a critical role in initiating immune responses by presenting antigen and clearance. The macrophages can be targeted for immunomodulation beneficial microbes, such as probiotics. aim of this study is to investigate the protective effect Saccharomyces boulardii against Clostridium perfringens infection avian macrophage cell line HD11. In study, HD11 were prestimulated with S. 6 h then infected C. 3 h. Results showed enhanced phagocytosis...
This study aims to explore the effects of modified montmorillonite (MMT, copper loading) on growth performance, gut microbiota, intestinal barrier, antioxidative capacity and immune function broilers. Yellow-feathered broilers were randomly divided into control (CTR), (MMT), antibiotic (ANTI) groups. Results revealed that MMT supplementation increased BW ADG decreased F/R during 63-day experiment period. 16S rRNA sequencing showed modulated cecal microbiota composition by increasing relative...
This letter reports on the fabrication and electrical characterization of wafer-fused GaAs/Si heterojunctions. A detailed study effect surface preparation bonding GaAs to Si was performed. The current–voltage (I–V) characteristics both n-GaAs/n-Si p-GaAs/p-Si were measured from 77 K room temperature. forward I–V analyzed using a numerical model that includes thermionic emission across heterojunction. Specifically, heterointerface high quality obtained by direct hydrophobic bonding.
Large-scale use of antimicrobials in agriculture and medicine contributes to antibiotic residues raw foods, the spread antimicrobial resistance (AMR) drug pollution, which seriously threatens human health imposes significant economic burdens on society, suggesting need for novel therapeutic options that prevent or control zoonoses. In this study, four probiotics were selected assess their capability alleviate pathogen-induced damage. Results showed a simulated gastrointestinal juice bile...
Clostridium perfringens (C. perfringens) causes intestinal injury through overgrowth and the secretion of multiple toxins, leading to diarrhea necrotic enteritis in animals, including pigs, chickens, sheep. This study aimed investigate protective effects Lactobacillus plantarum (L. plantarum) Lac16 on C. infection-associated porcine epithelial cell line (IPEC-J2). The results showed that L. significantly inhibited growth perfringens, which was accompanied by a decrease pH levels. In...