Purpose To measure retinal nerve fiber layer (RNFL) thickness in a population-based setting. Methods In the Beijing Eye Study 2011 with 3468 individuals, RNFL was measured subgroup of 1654 (47.7%) study participants by spectral domain optical coherence tomography (iVue SD-OCT). Results Mean significantly (P<0.001) higher inferior sector (131.4±20.6 µm) than superior (126.1±19.1 µm), where it temporal (79.8±12.2 µm;P<0.001), nasal (75.1±12.6 µm;P<0.001). multivariate analysis, mean global...

Because the blood circulation system of retina and brain are closely related to each other, we examined whether stroke is associated with localized retinal nerve fiber layer defects (RNFLDs). Patients acute ischemic as part a hospital-based study group were compared participants population-based Beijing Eye Study. The was imaged by spectral-domain optical coherence tomography for detection RNFLDs. included 154 patients 2890 subjects from Study whom tomographic images data on previous...

Abstract Purpose The aim of this study was to measure retinal nerve fibre layer thickness ( RNFLT ) and its associated factors in a population‐based setting. Methods B eijing E ye S tudy 2011 included 3468 individuals. participants underwent spectral‐domain optical coherence tomography pectralis ® ; OCT )–assisted measurement the . For study, exclusion criteria were glaucoma, pseudoexfoliation, best‐corrected visual acuity &gt;0.5 log MAR , macular diseases, previous ocular surgery known...

To examine a potential association between longitudinal changes in intraocular pressure (IOP), arterial blood and body mass index (BMI) population-based setting.The Beijing Eye Study included 2355 subjects with an age of 45+ years who were examined 2006 2011. The participants underwent detailed ophthalmic examination including tonometry measurement BMI.Data on IOP, BMI measured 2011 available for 2257 (95.8%) mean 59.5 ± 9.7 years. change IOP was -1.25 2.26 mm Hg, -7.4 12.1 mmHg, 0.01 2.04...

A 57‐year‐old woman with refractory vasovagal syncope and a sinus pause of 6.8 seconds during tilt‐table test accepted the suggestion atrial vagal denervation. Radiofrequency pulses were delivered on positive reflex sites according to standard heart rate (HR) drop ≥20% after high frequency stimulation (HFS). The endpoint inexistence HR decrease at repeating HFS was achieved in 18 sites. No attacked 12 months three tests performed 1, 6, negative. Extensive ablation endocardium for denervation...

Close adaptation of the prosthesis to bone is key achieving optimal stability and fixation for total hip arthroplasty (THA). However, there have been no adequate studies morphology, especially in different races. The aim this study was analyze geometry acetabulum proximal femur people from South China, based on three-dimensional reconstruction, detect differences between population subsets. CT scans were performed 80 healthy volunteers (160 hips) comprising 40 males (80 females hips). images...

Purpose.: To assess the 10-year incidence of pterygium and associated factors in adult Chinese. Methods.: The population-based, longitudinal Beijing Eye Study, which included 4439 subjects (age: 40+ years) 2001, was repeated 2011 with 2695 participating (66.4% survivors). Eyes a 2001 (n = 90) were additionally excluded. study participants underwent detailed ophthalmic examination, including slit-lamp examination for detection pterygia corneal photography measurement pterygia. Results.:...

Objective To assess the prevalence of localized retinal nerve fiber layer defects (LRNFLD) and associated factors in adult Chinese. Methods The population-based Beijing Eye Study 2011 included 3468 individuals (mean age: 64.6±9.8 years (range: 50–93 years)). study participants underwent a detailed ophthalmological examination including spectral-domain optical coherence tomography (SpectralisR-OCT) assisted measurement RNFL. A LRNFLD was defined as sector which RNFL contour line dipped into...

Subtotal facial nerve decompression seems effective to prevent further episodes of palsy and promote recovery for recurrent in Melkersson Rosenthal syndrome (MRS). The main inflammatory sites MRS may be the mastoid segment, tympanic geniculate ganglion, labyrinthine segment.To present our surgical experience preventing improving patients with MRS.We performed transmastoid subtotal on eight MRS. They were followed up 3.3 years average (range 2-5 years).There no attacks any cases. Seven cases...

Background Due to the axial elongation–associated changes in optic nerve and retina high myopia, traditional methods like disc evaluation visual field are not able correctly differentiate glaucomatous lesions. It has been clinically challenging detect glaucoma highly myopic eyes. Objective This study aimed develop a neural network adjust for dependence of peripapillary retinal fiber layer (RNFL) thickness (RNFLT) profile on age, gender, ocular biometric parameters evaluate network’s...

Objective: To investigate the relationships among illness perception, medication beliefs and adherence in primary angle closure glaucoma patients. Methods: It was a cross-sectional study. Morisky 8-item Medication Adherence Questionnaire Chinese Revised, Brief Illness Perceptions Questionnaire, Specific Section of Beliefs about Medicine Revised were administered to 156 patients from Tianjin Eye Hospital. Chi-square test used analyze types glaucoma, gender, prescription complexity, medicine...

Objective:To identify the chemical components in traditional Chinese herbal medicine Ginseng by high performance liquid chromatography diode array detector (HPLC-DAD) and High chromatography-time of flight mass spectrometry (HPLC-TOF/MS).Methods: An Agilent Zorbax XDB-Cl8 column (250 mm×4.6 mm,5 μm) was used for isolation identification with a mobile phase acetonitrile water gradient elution.A program as follows:1-35 min,19% A; 35-55 min,19%-29% 55-70 min,29% 70-110 min,29%-40% 110-150...

The study was aim to assess the impact of biochanin A on oral bioavailability and pharmacokinetics (PK) saquinavir (SQV), a substrate P-glycoprotein (P-gp), in rats. 10 male rats were randomized into 2 groups equal size, administered orally 30 mg/kg SQV with or without 20 A. PK assessed using non-compartmental analysis. Results revealed that area under plasma concentration-time curve from time zero infinity (AUC0-∞) reduced by 51.39% (P=0.038); while apparent systemic clearance (CL/F)...

Aims To investigate the distribution and associations of circumpapillary retinal nerve fibre layer thickness (RNFLT) profile, characterised as peak height position, in healthy eyes. Methods 667 participants (294 male) were randomly selected from Beijing Eye Study 2011. RNFLT was measured at 768 points 3.4 mm position using spectral-domain optical coherence tomography (OCT). The location superior temporally (Peak ST ), nasal SN ) inferior temporal IT assessed. Results thickest Peak (194±25...

Purpose To investigate the clinical characteristics of retinal detachment in congenital glaucoma and related surgical treatments. Methods 28 patients(30eyes)with suffering from were reviewed retrospectively. Results 26 eyes which undergone treatments anatomic recovered. The postoperative rise intraocular pressure took place all eyes. Follow-up was made on 20 patients(21 eyes), recurrent 5 final visual acuity increased 9 eyes, 14 normal. Conclusion area degree proliferative vitreoretinopathy...

Objective: To evaluate the imaging features of otosclerosis based on10 μm otology CT. Methods: Data 27 patients with (51 sides) in Beijing Friendship Hospital, Capital Medical University from October 2020 to July 2021 were retrospectively collected, including 9 males and 18 females age ffrom 22 70 (42±12) years. All underwent 10 CT examination surgical treatment. The types, amounts involved sites analyzed sensitivity diagnosing evaluated. Results: Fenestral type accounted for 49.0% (25/51...

With people's understanding and development of autoimmune-related diseases the nervous system, level diagnosis treatment has improved significantly. However, etiology some autoimmune system is still unknown. There a close relationship between gut microbiota immunity. The research discussion on flora will help clarify pathogenesis prevent progress in field preventive medicine. This article summarizes latest order to provide new...

Objective: To evaluate the morphology of isthmus vestibular aqueduct (VA) and its relationship with occurrence, course Meniere's disease (MD) degree hearing loss based on 10 μm otology CT. Methods: A total 13 patients MD in Beijing Friendship Hospital, Capital Medical University from October 2020 to July 2021, including 4 males 9 females, age 16 77 (56±16) years, were prospectively enrolled. All underwent CT examination. The included lesion side was affected group (14 sides), non-lesion...