- Neural and Behavioral Psychology Studies
- Neural dynamics and brain function
- Functional Brain Connectivity Studies
- Schizophrenia research and treatment
- Visual perception and processing mechanisms
- EEG and Brain-Computer Interfaces
- Mental Health Treatment and Access
- Mental Health and Psychiatry
- Nicotinic Acetylcholine Receptors Study
- Child and Adolescent Psychosocial and Emotional Development
- Health, psychology, and well-being
- Hallucinations in medical conditions
- Bipolar Disorder and Treatment
- Receptor Mechanisms and Signaling
- Psychiatric care and mental health services
- Healthcare Decision-Making and Restraints
- Healthcare Systems and Public Health
- Global Socioeconomic and Political Dynamics
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Spatial Neglect and Hemispheric Dysfunction
- Aesthetic Perception and Analysis
- Neurotransmitter Receptor Influence on Behavior
- Body Image and Dysmorphia Studies
- Face Recognition and Perception
- Mental Health Research Topics
Tbilisi State Medical University
2015-2024
Agricultural University of Georgia
2013-2024
Free University of Tbilisi
2018-2024
Tartu University Hospital
2021
Tbilisi State University
2018
Global Initiative on Psychiatry
2014
Rutgers, The State University of New Jersey
2014
University of Georgia
2013
Abstract Background The COVID-19 pandemic caused an unprecedented worldwide crisis affecting several sectors, including health, social care, economy and society at large. World Health Organisation has emphasized that mental health care should be considered as one of the core sectors within overall response. By March 2020, recommendations for organization services across Europe have been developed by national international professional associations. Methods European Psychiatric Association...
Many of us “see red,” “feel blue,” or “turn green with envy.” Are such color-emotion associations fundamental to our shared cognitive architecture, are they cultural creations learned through languages and traditions? To answer these questions, we tested emotional colors in 4,598 participants from 30 nations speaking 22 native languages. Participants associated 20 emotion concepts 12 color terms. Pattern-similarity analyses revealed universal (average similarity coefficient r = .88)....
Despite well-established sex differences for cognition, audition, and somatosensation, few studies have investigated whether there are also in visual perception. We report the results of fifteen perceptual measures (such as acuity, backward masking, contrast detection threshold or motion detection) a cohort over 800 participants. On six tests, males significantly outperformed females. no test did females outperform males. Given this heterogeneity effects, it is unlikely that due to any...
Schizophrenia is a complex psychiatric disorder and many of the factors contributing to its pathogenesis are poorly understood. In addition, identifying reliable neurophysiological markers would improve diagnosis early identification this disease. The 22q11.2 deletion syndrome (22q11DS) one major risk factor for schizophrenia. Here, we show further evidence that deviant temporal dynamics EEG microstates potential marker by showing resting state patterns 22q11DS similar those found in...
Schizophrenic patients suffer from many deficits including visual, attentional, and cognitive ones. Visual are of particular interest because they at the fore-end information processing can provide clear examples interactions between sensory, perceptual, higher functions. in schizophrenic often attributed to impairments dorsal (where) rather than ventral (what) stream visual processing. We used a visual-masking paradigm which matched controls discriminated small vernier offsets. analyzed...
Abstract Background. Compulsory admission procedures of patients with mental disorders vary between countries in Europe. The Ethics Committee the European Psychiatric Association (EPA) launched a survey on involuntary 40 to gather information from all National Associations that are members EPA develop recommendations for improving processes and promote voluntary care. Methods. focused legislation admissions key actors involved procedure as well most common reasons admissions. Results. We...
Despite the increasing burden of mental, neurological, and substance use (MNS) disorders, a significant treatment gap for these disorders continues to exist across world, especially in low- middle-income countries. To bridge gap, World Health Organization developed launched Mental Gap Action Programme (mhGAP) mhGAP Intervention Guide (mhGAP-IG) help train non-specialists deliver care. Although mhGAP-IG has been used more than 100 countries in-service training, its implementation pre-service...
Background To understand the genetics of schizophrenia, a hunt for so-called intermediate phenotypes or endophenotypes is ongoing. Visual masking has been proposed to be such an endophenotype. However, no systematic study conducted yet prove this claim. Here, we present first showing that meets most important criteria Methodology/Principal Findings We tested 62 schizophrenic patients, 39 non-affected first-degree relatives, and 38 healthy controls in shine-through paradigm and, addition,...
Abstract Research on schizophrenia typically focuses one paradigm for which clear-cut differences between patients and controls are established. Great efforts made to understand the underlying genetical, neurophysiological, cognitive mechanisms, eventually may explain clinical outcome. One tacit assumption of these “deep rooting” approaches is that paradigms tap into common representative aspects disorder. Here, we analyzed resting-state electroencephalogram (EEG) 121 75 controls. Using...
Abstract Background and Hypothesis For a long time, it was proposed that schizophrenia (SCZ) patients rely more on sensory input less prior information, potentially leading to reduced serial dependence—ie, influence of stimuli in perceptual tasks. However, existing evidence is constrained few paradigms, whether dependence reflects general characteristic the disease remains unclear. Study Design We investigated 26 SCZ 27 healthy controls (CNT) evaluate classic visual orientation adjustment...
The obvious symptoms of schizophrenia are cognitive and psychopathological nature. However, affects also visual processing which becomes particularly evident when stimuli presented for short durations followed by a masking stimulus. Visual deficits great interest because they might be related to the genetic variations underlying disease (endophenotype concept). usually attributed specific dysfunctions system such as hypo- or hyper-active magnocellular system. Here, we propose that...
The nicotinic system is involved in the pathophysiology of schizophrenia. However, very little known about its genetic basis and how it relates to clinical symptoms potentially pharmacological intervention. Here, we investigated five single nucleotide polymorphisms (SNPs) [rs3826029] [rs2337506] [rs982574] [rs904952] [rs2337980] cholinergic receptor gene, alpha 7 subunit (CHRNA7) their association We found an with rs904952 (p=0.009) a German sample 224 schizophrenic patients healthy control...
Abstract Recent work suggests that the individual alpha peak frequency (IAPF) reflects temporal resolution of visual processing: individuals with higher IAPF can segregate stimuli at shorter intervals compared to those lower IAPF. However, this evidence mainly comes from studies focusing on short intervals, stimulus onset asynchronies (SOA) rarely extending beyond a single cycle (e.g., ~100 ms). Here, we investigated relationship between and performance in backward masking (VBM), which...
Visual backward masking (VBM) deficits are candidate endophenotypes of schizophrenia indexing genetic liability the disorder. In VBM, a target is followed by mask that deteriorates perception. Schizophrenia patients and, to lesser extent, their unaffected relatives show strong and reproducible VBM deficits. patients, associated with strongly decreased amplitudes in evoked-related potentials (ERPs). Here, unveil neural mechanisms schizophrenia, circumventing illness-specific confounds, we...
Despite the increasing burden of mental disorders, a lot people worldwide suffer gap in receiving necessary care these countries. To close this gap, WHO has developed mhGAP training modules aimed at scaling up health and substance use disorders services, especially low- middle-income This article presents experience implementing Mental Health Gap Action Programme (mhGAP) Ukraine, Armenia, Georgia, Kyrgyz Republic. Data were gathered from an electronic questionnaire administered to...